Abstract：
:The regulatory aspects of generic drug substitution and the scientific concepts that serve as the basis for generic drug approval are discussed, with emphasis on the source of therapeutic equivalence information compiled by the Food and Drug Administration in Approved Drug Products with Therapeutic Equivalence Evaluations. The Food and Drug Administration's determination of bioequivalence for immediate-release and extended-release dosage forms is summarized, with a discussion of the underlying assumptions and current issues regarding bioequivalence testing. Medical practitioners must comply with the regulations stated in each state's Pharmacy Practice Act when allowing generic substitution and should ensure that the substituted product is therapeutically equivalent to the prescribed product.
journal_name
Mil Medjournal_title
Military medicineauthors
Henderson JD,White GL Jrsubject
Has Abstractpub_date
1998-04-01 00:00:00pages
193-7issue
4eissn
0026-4075issn
1930-613Xjournal_volume
163pub_type
杂志文章abstract：:Meals ready to eat (MRE) have undergone many revisions of their origins in the trench ration from World War I. The MRE was implemented in 1980. Its design allows extended storage and easy, safe meal preparation. MRE sodium content varies by meal and may range from 1.6 g/meal to 2.3 g/meal. The average MRE contains 1,2...
journal_title：Military medicine
pub_type： 杂志文章
doi：10.7205/milmed-d-09-00049
更新日期：2010-03-01 00:00:00
abstract：:A medical readiness training exercise was conducted in conjunction with Task Force Bravo in Honduras during July and August 2000. Surgical teams from Madigan Army Medical Center performed 46 major pelvic reconstructive surgical procedures and treated more than 300 patients. The mission was an exceptional training oppo...
journal_title：Military medicine
pub_type： 杂志文章
doi：
更新日期：2002-01-01 00:00:00
abstract：BACKGROUND:It was recently noted that a shortened activated partial thromboplastin time (aPTT) is associated with increased venous thromboembolic events. The prevalence of aPTT shortening remains unknown. METHODS:We conducted a retrospective analysis of aPTT results over a 2-month period. These results were not associ...
journal_title：Military medicine
pub_type： 杂志文章
doi：10.7205/milmed-d-10-00165
更新日期：2011-08-01 00:00:00
abstract：:A case of a woman presenting with an acute tension pneumothorax during a Navy humanitarian mission in East Timor is presented. The patient was treated at a local rural clinic run by our medical team. Prompt insertion of a chest tube saved the woman's life; however, there were no chest tube drains available. A field ch...
journal_title：Military medicine
pub_type： 杂志文章
doi：10.7205/milmed.169.5.403
更新日期：2004-05-01 00:00:00
abstract：:A diminution in the anticoagulant effect of IV heparin with concomitant use of IV nitroglycerin has been reported. However, recent reports have disputed the existence of this interaction. The objective of this study was to assess the potential interaction of these agents in a clinical setting. Forty-five patients hosp...
journal_title：Military medicine
pub_type： 临床试验,杂志文章
doi：
更新日期：1994-08-01 00:00:00
abstract：BACKGROUND:Addition of an oxygen concentrator into a control loop furthers previous work in autonomous control of oxygenation. Software integrates concentrator and ventilator function from a single control point, ensuring maximum efficiency by placing a pulse of oxygen at the beginning of the breath. We sought to verif...
journal_title：Military medicine
pub_type： 杂志文章
doi：10.7205/MILMED-D-15-00150
更新日期：2016-05-01 00:00:00
abstract：:After the conclusion of major ground combat operations during Operation Iraqi Freedom, the focus of the mission changed, although intense armed conflict continued. Included in this mission was management of security detainees, including provision of their medical care. We retrospectively reviewed the admission records...
journal_title：Military medicine
pub_type： 杂志文章
doi：10.7205/milmed.170.6.501
更新日期：2005-06-01 00:00:00
abstract：:Spontaneous pneumomediastinum (SPM) with associated subcutaneous emphysema is an uncommon and generally benign condition. We describe an occurrence of SPM that occurred from yelling in a U.S. Marine Corps Drill Instructor. The patient describes yelling at Marine recruits the day prior when he felt a pop "behind his no...
journal_title：Military medicine
pub_type： 杂志文章
doi：10.7205/milmed-d-12-00243
更新日期：2012-11-01 00:00:00
abstract：STUDY OBJECTIVE:Many studies have shown that community-acquired methicillin-resistant Staphylococcus aureus (CAMRSA) is a very prevalent organism. However, no data have been published to date with regard to CAMRSA prevalence in patients presenting to the emergency department (ED) of a military medical facility. Our obj...
journal_title：Military medicine
pub_type： 杂志文章
doi：10.7205/milmed.173.10.945
更新日期：2008-10-01 00:00:00
abstract：:The type and number of injuries sustained by soldiers of a Croatian Army brigade in an offensive action during the war in Croatia (1991/1992) were analyzed according to the mechanism of wounding. About 1,000 soldiers participated in a 6-hour offensive action in a flat, partially swampy, and wooded area, convenient for...
journal_title：Military medicine
pub_type： 杂志文章
doi：
更新日期：1998-06-01 00:00:00
abstract：:Army health care personnel play a key role in the Army's Family Advocacy Program, yet little is known about their beliefs toward domestic violence. This study surveyed the beliefs of selected Army Medical Department personnel concerning the extent, nature, causes, and management of spouse abuse. The study suggests tha...
journal_title：Military medicine
pub_type： 杂志文章
doi：
更新日期：1991-09-01 00:00:00
abstract：:Dietary supplement use is common among military service members; approximately 17 to 20% report using high-risk weight-loss, performance-enhancing, and bodybuilding supplements. To date, no overarching policy or program has been approved or implemented to inform service members or educate health care providers on the ...
journal_title：Military medicine
pub_type： 杂志文章
doi：10.7205/milmed-d-12-00249
更新日期：2012-12-01 00:00:00
abstract：INTRODUCTION:There is a widespread and long-held belief in the submarine community that submariners father more daughters than the general population. The U.S. Sex Ratio at birth (males/females) has remained around 1.05 since the early 2000s. Limited evidence exists that certain environmental exposures including chemic...
journal_title：Military medicine
pub_type： 杂志文章
doi：10.1093/milmed/usy390
更新日期：2019-07-01 00:00:00
abstract：:Isoniazid prophylaxis is a major part of the U.S. Air Force tuberculosis (TB) screening program and is closely tied to the efforts to eliminate TB. If a facility has a low prevalence rate of TB and there is no sound epidemiological evidence to rule out a false-positive TB skin test, a higher threshold for what constit...
journal_title：Military medicine
pub_type： 杂志文章
doi：
更新日期：1996-07-01 00:00:00
abstract：INTRODUCTION:The prevalence of mild traumatic brain injury (mTBI) is commonly estimated based on indirect metrics such as emergency department visits and self-reporting tools. The study of postconcussive symptoms faces similar challenges because of their unspecific character and indistinct causality. In this article, w...
journal_title：Military medicine
pub_type： 杂志文章
doi：10.1093/milmed/usaa504
更新日期：2020-12-03 00:00:00
abstract：:The objective of this study was to assess the impact of a pilot nutrition intervention program on knowledge, attitudes, and behaviors of female combat soldiers in basic training serving in the Israeli army and to determine changes in nutrient intake. Seventy recruits participated in the intervention. Anthropometric me...
journal_title：Military medicine
pub_type： 杂志文章
doi：10.7205/MILMED-D-12-00439
更新日期：2013-05-01 00:00:00
abstract：:Four cases of splenic infarction/sequestration in sickle cell trait (SCT) patients are presented. All four patients were undergoing moderate exercise at elevations ranging from 5,500 to 12,000 feet. The patients include two African-American males, a Hispanic male, and a white female. All four presented with the acute ...
journal_title：Military medicine
pub_type： 杂志文章,评审
doi：
更新日期：1999-03-01 00:00:00
abstract：:Data are reported from a sample of 2,991 spouse physical abusers who received Air Force Family Advocacy Program (FAP) services and who volunteered to complete program evaluation measures that were administered before and after treatment and at a 6-month follow-up. As expected, after treatment compared with before trea...
journal_title：Military medicine
pub_type： 杂志文章
doi：
更新日期：2002-06-01 00:00:00
abstract：:The purpose of this case presentation is to discuss right upper quadrant pain as an atypical presenting symptom in pulmonary infarction and review the typical computed tomography (CT) imaging features of pulmonary infarction to improve diagnostic accuracy. Pulmonary infarction results from occlusion of distal arterial...
journal_title：Military medicine
pub_type： 杂志文章
doi：10.1093/milmed/usy128
更新日期：2018-11-01 00:00:00
abstract：:Few studies have evaluated high altitude headache (HAH) and acute mountain sickness (AMS) in military populations training at moderate (1,500-2,500 m) to high altitudes (>2,500 m). In the current study, researchers interviewed active duty personnel training at Marine Corps Mountain Warfare Training Center. Participant...
journal_title：Military medicine
pub_type： 杂志文章
doi：10.7205/milmed-d-12-00007
更新日期：2012-08-01 00:00:00
abstract：:In December 1913, a board of medical officers was appointed to adapt new U.S. Army equipment to the needs of the Hospital Corps. One of the improvements concerned substitution of the satchel-like Hospital Corps pouch used to carry first aid equipment. A waist belt with 10 pockets, known as the medical belt, was devise...
journal_title：Military medicine
pub_type： 历史文章,杂志文章
doi：10.7205/MILMED-D-15-00390
更新日期：2016-10-01 00:00:00
abstract：:The purpose of this study was to examine physical work performance, energy cost, and physiological fatigue in military personnel during simulated operational conditions. Using a within-subject, repeated-measures design, 34 military personnel volunteered to undergo two experimental conditions: with body armor (BA+) and...
journal_title：Military medicine
pub_type： 杂志文章
doi：10.7205/milmed.173.9.817
更新日期：2008-09-01 00:00:00
abstract：:Knowledge of the impact of childhood psychosocial problems on success in military service is scarce. The purpose of the study was to assess whether childhood psychosocial problems are associated with suitability for military service. The subjects were 2,622 Finnish boys born in 1981. They were first assessed with the ...
journal_title：Military medicine
pub_type： 杂志文章
doi：10.7205/milmed.173.2.146
更新日期：2008-02-01 00:00:00
abstract：:Not since 1945 has the world experienced nuclear warfare, although there has been the threat of nuclear terrorism and a large number of nuclear/radiological accidents. Most people fear a nuclear/radiological threat even more than a conventional explosion due both to their inability to perceive the presence of radiatio...
journal_title：Military medicine
pub_type：
doi：
更新日期：2001-12-01 00:00:00
abstract：:Severely injured patients have difficulty recalling their intensive care unit (ICU) experience which may contribute to emotional trauma. An ICU patient journal contains a short summary of key events during the ICU stay, and has been shown to improve emotional well-being. This project evaluated the feasibility and perc...
journal_title：Military medicine
pub_type： 杂志文章
doi：10.7205/MILMED-D-15-00210
更新日期：2016-08-01 00:00:00
abstract：:This article looks at the historical rationale behind the development of the healthcare administration structure currently used at Walter Reed Army Medical Center (WRAMC). This type of healthcare administration structure is unique to WRAMC and is not found in any other United States Army Medical Department healthcare ...
journal_title：Military medicine
pub_type： 杂志文章
doi：
更新日期：1990-11-01 00:00:00
abstract：:The purpose of this article was to give a brief synopsis of the background and history of forensic nursing and how it can be translated into a military application. The unique setting of military health care and equally distinctive stressors placed upon members of the military calls for greater commitment by the Depar...
journal_title：Military medicine
pub_type： 杂志文章
doi：10.7205/milmed.173.1.42
更新日期：2008-01-01 00:00:00
abstract：:Operations Just Cause and Desert Storm were of relatively brief duration; however, severe wounds were produced that required complex reconstructive procedures. This paper describes the type of wounds managed in theater and subsequently at three U.S. military medical centers. Specific reconstructive techniques included...
journal_title：Military medicine
pub_type： 杂志文章
doi：
更新日期：1995-02-01 00:00:00
abstract：Introduction:Bioelectrical impedance analysis (BIA) is a practical and rapid method for making a longitudinal analysis of changes in body composition. However, most BIA validation studies have been performed in a clinical population and only at one moment, or point in time (cross-sectional study). The aim of this study...
journal_title：Military medicine
pub_type： 杂志文章
doi：10.1093/milmed/usx223
更新日期：2018-07-01 00:00:00
abstract：:This case study describes the rehabilitation of 10 active duty U.S. soldiers with exertional rhabdomyolysis. The pathophysiology of rhabdomyolysis is discussed. The initial management is concerned with accurate diagnosis and monitoring of laboratory values to prevent complications. Active and passive range of motion, ...
journal_title：Military medicine
pub_type： 杂志文章
doi：
更新日期：1996-09-01 00:00:00
