Evaluation of lipid-coated microbubbles as a delivery vehicle for Taxol in brain tumor therapy.

abstract：:This study examines the pathophysiology of stroke secondary to focal cerebral ischemia. The interaction of arachidonic acid metabolites and polyamines, a class of ubiquitous ornithine-derived molecules with important membrane effects on edema, Ca++-dependent endocytosis, platelet function, and prostaglandin (PG) forma...

journal_title：Neurosurgery

authors： Dempsey RJ,Roy MW,Meyer K,Tai HH,Olson JW

更新日期：1985-10-01 00:00:00

abstract：OBJECTIVE AND IMPORTANCE:Endovascular stents have been successfully used in the treatment of fusiform and dissecting aneurysms of the peripheral circulation and extracranial carotid and vertebral arteries. Technical limitations related to the inability to navigate the stent and the delivery system through tortuous vasc...

journal_title：Neurosurgery

authors： Mericle RA,Lanzino G,Wakhloo AK,Guterman LR,Hopkins LN

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND:Although in the developed world the intracranial pressure (ICP) monitor is considered the standard of care for patients with severe traumatic brain injury (TBI), its usefulness to direct treatment decisions has never been tested rigorously. OBJECTIVE:The primary focus was to conduct a high-quality, randomiz...

journal_title：Neurosurgery

authors： Chesnut RM,Temkin N,Carney N,Dikmen S,Pridgeon J,Barber J,Celix JM,Chaddock K,Cherner M,Hendrix T,Lujan S,Machamer J,Petroni G,Rondina C,Videtta W

更新日期：2012-12-01 00:00:00

abstract：:There were 15 cases of multiple meningiomas in a consecutive series of 168 cases of meningioma studied by computed tomography during the last 5 years. This incidence of 8.9% is significantly higher than the 1 to 3% incidence reported previously. A brief clinical survey of the 15 cases and a description of the location...

journal_title：Neurosurgery

authors： Lusins JO,Nakagawa H

更新日期：1981-08-01 00:00:00

abstract：:A large meningioma in the cerebellopontine angle manifested itself as a contralateral hemifacial spasm. On computed tomographic and magnetic resonance imaging scans, the brain stem was markedly displaced and distorted by the tumor. After total removal of the meningioma, the hemifacial spasm completely disappeared. ...

journal_title：Neurosurgery

authors： Rhee BA,Kim TS,Kim GK,Leem WL

更新日期：1995-02-01 00:00:00

abstract：INTRODUCTION:We evaluated the feasibility, usefulness, and limitations of near-infrared indocyanine green (ICG) videoangiography during procedures involving the extracranial vertebral artery (VA). METHODS:Nine patients (2 women, 7 men; mean age, 55 years) were evaluated at 2 neurosurgical centers. Near-infrared ICG vi...

journal_title：Neurosurgery

authors： Bruneau M,Sauvageau E,Nakaji P,Vandesteene A,Lubicz B,Chang SW,Balériaux D,Brotchi J,De Witte O,Spetzler RF

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVE:Balancing the benefits of extensive tumor resection with the consequence of potential postoperative deficits remains a challenge in malignant astrocytoma surgery. Although studies have suggested that increasing extent of resection may benefit survival, the effect of new postoperative deficits on survival rema...

journal_title：Neurosurgery

authors： McGirt MJ,Mukherjee D,Chaichana KL,Than KD,Weingart JD,Quinones-Hinojosa A

更新日期：2009-09-01 00:00:00

abstract：:The frequency spectrum of the cerebrospinal fluid (CSF) pulse and the amplitude transfer function between arterial and CSF pressures were measured from the cisterna magna of anesthetized, artificially ventilated cats when the intracranial pressure (ICP) was raised by saline infusion. The spectrum of CSF pulsation was ...

journal_title：Neurosurgery

authors： Takizawa H,Gabra-Sanders T,Miller JD

更新日期：1987-03-01 00:00:00

abstract：OBJECTIVE:We sought to determine the risk of adverse outcome after contemporary surgical treatment of patients with unruptured intracranial aneurysms in the United States. Patient, surgeon, and hospital characteristics were tested as potential outcome predictors, with particular attention to the surgeon's and hospital'...

journal_title：Neurosurgery

authors： Barker FG 2nd,Amin-Hanjani S,Butler WE,Ogilvy CS,Carter BS

更新日期：2003-05-01 00:00:00

abstract：:The residency program in neurological surgery at Northwestern University was founded in 1924 by Loyal Davis and was formally accredited by the American Board of Neurological Surgery in 1946. Allen Kanavel, mentor to Davis, was one of the original members of the Society of Neurological Surgeons. Five individuals have s...

journal_title：Neurosurgery

authors： Engelhard HH,Grant J,Ciric IS,Wetzel NC,Batjer HH

更新日期：1998-10-01 00:00:00

abstract：OBJECTIVE:There are numerous reports on the surgical treatment of trigeminal neuralgia, but the studies do not use uniform outcome measures, which makes it difficult for patients and clinicians to determine which treatment may be most appropriate. The objectives of this study were to set quality criteria and standards ...

journal_title：Neurosurgery

authors： Zakrzewska JM,Lopez BC

更新日期：2003-07-01 00:00:00

abstract：:The operative and histopathological findings in 31 cases of intracranial meningioma after preoperative embolization with Gelfoam and/or lyophilized dura mater are reported. Removal of the tumor after embolization was facilitated in those meningiomas fed exclusively or mainly by branches of the external carotid artery ...

journal_title：Neurosurgery

authors： Richter HP,Schachenmayr W

更新日期：1983-09-01 00:00:00

abstract：:A case of spontaneous intracranial hemorrhage associated with a meningioma is presented. Intracranial hemorrhage has been reported to be associated with meningioma in 45 cases. A comprehensive review of the subject is presented. The importance of the diagnosis of associated hemorrhage and subsequent surgical intervent...

journal_title：Neurosurgery

authors： Kohli CM,Crouch RL

更新日期：1984-08-01 00:00:00

abstract：OBJECTIVE:This study prospectively examined neuropsychological functioning in 2300 collegiate football players from 10 National Collegiate Athletic Association Division A universities. The study was designed to determine the presence and duration of neuropsychological symptoms after mild head injury. METHODS:A nonequi...

journal_title：Neurosurgery

authors： Macciocchi SN,Barth JT,Alves W,Rimel RW,Jane JA

更新日期：1996-09-01 00:00:00

abstract：:The use OF chemotherapy to treat patients with brain metastases has been viewed historically with skepticism. To date, a survival benefit has not been demonstrated with the use of systemic chemotherapy in patients with brain metastases. However, the introduction of novel agents and delivery techniques warrants a reexa...

journal_title：Neurosurgery

authors： Peereboom DM

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:The optimal magnetic resonance angiography (MRA) sequence for assessing the aneurysm occlusion state or in-stent flow after endovascular coiling is not well established. OBJECTIVE:To evaluate the diagnostic performance of pointwise encoding time reduction with radial acquisition (PETRA)-MRA in patients who ...

journal_title：Neurosurgery

authors： You SH,Kim B,Yang KS,Kim BK,Ryu J

更新日期：2021-01-13 00:00:00

abstract：:Anterior cervical instrumentation as an adjunct to bone fusion has an important role in cervical spine surgery. Posterior vertebral body cortex purchase is strongly recommended in the use of the Caspar system, although few biomechanical data exist to validate this requirement. In this study, Caspar screws were placed ...

journal_title：Neurosurgery

authors： Maiman DJ,Pintar FA,Yoganandan N,Reinartz J,Toselli R,Woodward E,Haid R

更新日期：1992-12-01 00:00:00

abstract：:Intracranial pressure sensors and subdural and subgaleal sensing tambours were used to measure the pressure difference between the intracranial and subgaleal spaces in two monkeys. The pressure differential was transmitted to fluid bathing a piston, to which an isotope source (145Pm) was attached. The radiation signal...

journal_title：Neurosurgery

authors： Meyer GA,Millis RM,Budzinski J

更新日期：1978-01-01 00:00:00

abstract：:A case of cerebellopontine angle petrous bone osteoma manifesting as homolateral trigeminal neuralgia and causing a mild brain stem compression is presented. The literature concerning osteomas and particularly those affecting the temporal bone is reviewed. This is the second report of an osteoma located on the inner s...

journal_title：Neurosurgery

authors： Ruelle A,Datti R,Andrioli G

更新日期：1994-12-01 00:00:00

abstract：OBJECTIVE:This study aimed to examine early effects of ex vivo-expanded bone marrow-derived endothelial progenitor cells (EPCs) on focal cerebral ischemia-reperfusion injury. METHODS:EPCs were obtained from mononuclear cells of autologous bone marrow of a rat. After culture on fibronectin-coated dishes for 10 to 14 da...

journal_title：Neurosurgery

authors： Ohta T,Kikuta K,Imamura H,Takagi Y,Nishimura M,Arakawa Y,Hashimoto N,Nozaki K

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:The goals of treating Koos grade IV vestibular schwannomas are to relieve brainstem compression, preserve or restore neurological function, and achieve long-term tumor control while minimizing tumor- and treatment-related morbidity. OBJECTIVE:To propose a treatment paradigm involving the intentional near-to...

journal_title：Neurosurgery

authors： Zumofen DW,Guffi T,Epple C,Westermann B,Krähenbühl AK,Zabka S,Taub E,Bodmer D,Mariani L

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVE:The release of results of International Subarachnoid Aneurysm Trial in 2003 caused a shift in the paradigm of management of ruptured intracranial aneurysms. The cases selected for microsurgical clipping nowadays are usually those patients with aneurysms that are not suitable for embolization, and are often co...

journal_title：Neurosurgery

authors： Wong GK,Zhu CX,Ahuja AT,Poon WS

更新日期：2007-09-01 00:00:00

abstract：OBJECTIVE:Conflicting reports have been published with regard to the relationship between the efficacy of p53 gene therapy and the p53 status of gliomas. In this study, we evaluated whether U-87MG glioma cells harboring wild-type p53 and U251 and U-373MG glioma cells harboring mutated p53 demonstrate different sensitiv...

journal_title：Neurosurgery

authors： Shinoura N,Sakurai S,Asai A,Kirino T,Hamada H

更新日期：2001-07-01 00:00:00

abstract：:Six arteriovenous malformations (AVMs) and five arterial aneurysms (AAs) were treated with either argon or neodymium:yttrium-aluminum-garnet laser irradiation; one AVM was treated with both. All AVMs were occluded completely, leaving adjacent tissue untouched and preserving the regional vascularization. Photocoagulati...

journal_title：Neurosurgery

authors： Fasano VA,Urciuoli R,Ponzio RM

更新日期：1982-12-01 00:00:00

abstract：BACKGROUND:Papillary meningioma (PM) is an uncommon meningioma subtype, and the clinical characteristics remain unclear. OBJECTIVE:To determine the clinical characteristics and prognosis of PM. METHODS:The clinical data of 30 PM patients were collected, the samples were reexamined, and the patients' prognoses were ba...

journal_title：Neurosurgery

authors： Wang XQ,Chen H,Zhao L,Li ST,Hu J,Mei GH,Jiang CC

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVE:Patients with partial or complete bilateral vertebral artery occlusion often present with signs and symptoms of transient ischemic attacks or infarction. Advances in phase contrast magnetic resonance imaging have led to noninvasive assessment of volumetric blood flow rates and direction that help in the worku...

journal_title：Neurosurgery

authors： Starke RM,Chwajol M,Lefton D,Sen C,Berenstein A,Langer DJ

更新日期：2009-04-01 00:00:00

abstract：:Three cases of primary infectious spondylitis, two caused by Staphylococcus aureus and one by tuberculosis, were diagnosed using the method previously described for automated percutaneous discectomy. All three patients, in whom biopsy using fine needle techniques previously was unsuccessful, had positive cultures from...

journal_title：Neurosurgery

authors： Onik G,Shang YL,Maroon J,Eichenblat M,Mercer D,Bailes JE

更新日期：1990-02-01 00:00:00

abstract：BACKGROUND:The lower thoracic spine is a complicated area within the vertebral column because of its anatomic complexity and inaccessibility. A variety of surgical procedures have been applied to access lower thoracic spinal lesions. When hard compressive pathologies are located on the ventral side of the dura, existin...

journal_title：Neurosurgery

authors： Lee SE,Jahng TA,Chung CK,Kim HJ

更新日期：2012-06-01 00:00:00

abstract：:A rare and serious complication of ventriculoperitoneal shunt is reported. A huge intraventricular hematoma was confirmed by computed tomography scanning and autopsy. This is the first report of such a complication in a newborn with hydrocephalus. ...

journal_title：Neurosurgery

authors： Kuwamura K,Kokunai T

更新日期：1982-03-01 00:00:00

abstract：:Experimental brain lesions were created in the left parietooccipital cortex of the albino rabbit through the intact dura mater with high radiating carbon dioxide laser energy (40-watt impacts of 0.5-second duration for a total of 4 seconds on a 12.5-mm surface). Behavior, intracranial pressure (ICP), systolic arterial...

journal_title：Neurosurgery

authors： Tiznado E,James HE,Kemper C

更新日期：1985-01-01 00:00:00