Caspase-9 transduction overrides the resistance mechanism against p53-mediated apoptosis in U-87MG glioma cells.

abstract：BACKGROUND:Papillary meningioma (PM) is an uncommon meningioma subtype, and the clinical characteristics remain unclear. OBJECTIVE:To determine the clinical characteristics and prognosis of PM. METHODS:The clinical data of 30 PM patients were collected, the samples were reexamined, and the patients' prognoses were ba...

journal_title：Neurosurgery

authors： Wang XQ,Chen H,Zhao L,Li ST,Hu J,Mei GH,Jiang CC

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVE:Major steps in the evolution of advanced neurosurgical techniques include microneurosurgery, neuroendoscopy and its minimally invasive variations, neuronavigation, and advanced intraoperative imaging. With traditional neuroendoscopic techniques (e.g., freehand endoscopy or the use of mechanical arms), definit...

journal_title：Neurosurgery

authors： Zimmermann M,Krishnan R,Raabe A,Seifert V

更新日期：2002-12-01 00:00:00

abstract：:Traditionally, neurosurgeons have responded to calls to treat new patients or address emergent, acute neurosurgical pathology in the hospitals they staff as part of their duty to the medical profession and community. Due to increasing financial pressures placed upon neurosurgical practice from hospitals and regulatory...

journal_title：Neurosurgery

authors： Babu MA,Stroink AR,Timmons SD,Orrico KO,Prall JA

更新日期：2019-04-01 00:00:00

abstract：:A newly designed cottonoid is fixed to the tip of the suction device by the negative pressure. It is especially useful during microsurgical procedures in areas crowded with neurovascular elements. The advantage of pressure-mounted cottonoids lies in the protection provided to the brain and neurovascular elements durin...

journal_title：Neurosurgery

authors： Arbit E

更新日期：1982-12-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to determine whether embryonic central nervous system transplants assisted cut dorsal root axons of adult rats to regenerate into the spinal cord. METHODS:Rats received transplants of embryonic spinal cord, hippocampus, or neocortex into dorsal quadrant cavities aspirated in the lum...

journal_title：Neurosurgery

authors： Itoh Y,Mizoi K,Tessler A

更新日期：1999-10-01 00:00:00

abstract：OBJECTIVE:Ischemia plays an important role in the development of pathological changes in nerve tissue, and restoration of blood flow results in injury (ischemia/reperfusion [I/R] injury) mediated by toxic oxygen free radicals. Trapidil is currently used as a coronary artery vasodilating agent and is also used for the p...

journal_title：Neurosurgery

authors： Bagdatoglu C,Saray A,Surucu HS,Ozturk H,Tamer L

更新日期：2002-07-01 00:00:00

abstract：OBJECTIVE:An intracranial aneurysm is an important acquired cerebrovascular disease that can cause a catastrophic subarachnoid hemorrhage. Despite modern therapy, most patients die or are left disabled as a direct result of a severe initial hemorrhage. The development of more effective treatment strategies depends on u...

journal_title：Neurosurgery

authors： Chyatte D,Bruno G,Desai S,Todor DR

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND:Joint-distraction and intra-operative manipulation surgeries to correct basilar invagination (BI) and atlantoaxial dislocation (AAD) are becoming standard procedures. However, current data are unable to aid in the understanding of normal and abnormal morphology of the C1/C2 joints. OBJECTIVE:To study variou...

journal_title：Neurosurgery

authors： Chandra PS,Goyal N,Chauhan A,Ansari A,Sharma BS,Garg A

更新日期：2014-12-01 00:00:00

abstract：:The authors report a rare sequelae of a skull fracture in an adult, a leptomeningeal cyst. A unique method for repairing this defect is described as well. ...

journal_title：Neurosurgery

authors： Halliday AL,Chapman PH,Heros RC

更新日期：1990-01-01 00:00:00

abstract：:The object of this study was to determine whether the addition of information on brain stem reflexes improves the prognostic precision of the Glasgow coma scale for patients with severe head trauma. The study is based on 109 patients with a Glasgow coma score of 7 or less during the first 24 hours after injury. The av...

journal_title：Neurosurgery

authors： Born JD,Albert A,Hans P,Bonnal J

更新日期：1985-05-01 00:00:00

abstract：OBJECTIVE:Carotid-cavernous fistulae are uncommon but well-documented sequelae of craniofacial trauma. A rare subset may arise from the posterior communicating artery instead of from the carotid artery proper. The presentation is similar to that of carotid-cavernous fistulae, with ocular pain, chemosis, and proptosis b...

journal_title：Neurosurgery

authors： Weaver KD,Ewend MG,Solander S

更新日期：2003-02-01 00:00:00

abstract：OBJECTIVE:To determine whether low-grade gliomas contain functional cortical activity more often than high-grade gliomas within radiologically defined abnormal tissue. METHODS:Patients with intra-axial cerebral lesions located in the vicinity of eloquent brain cortex preoperatively underwent magnetic source imaging. A...

journal_title：Neurosurgery

authors： Schiffbauer H,Ferrari P,Rowley HA,Berger MS,Roberts TP

更新日期：2001-12-01 00:00:00

abstract：:In patients with subarachnoid hemorrhage, delayed neurological deficits, often followed by infarction, are believed to result from ischemia caused by vasospasm. Cerebral blood flow (CBF) data have been useful in predicting the risk of vasospasm in these patients and in distinguishing those deficits caused by vasospasm...

journal_title：Neurosurgery

authors： Yonas H,Sekhar L,Johnson DW,Gur D

更新日期：1989-03-01 00:00:00

abstract：:PURPOSE: To describe the design and performance of a novel frameless system for radiosurgery. This technology, called image-guided radiosurgery (IGR), eliminates the need for stereotactic frame fixation by relating the identified lesion to radiographic landmarks. CONCEPT: IGR uses a lightweight x-band linear accelerat...

journal_title：Neurosurgery

authors： Adler JR Jr,Murphy MJ,Chang SD,Hancock SL

更新日期：1999-06-01 00:00:00

abstract：BACKGROUND:Although previous evidence suggests that the cognitive effects of concussions are cumulative, the effect of time interval between repeat concussions is largely unknown. OBJECTIVE:To determine the effect of time interval between repeat concussions on the cognitive function of mice. METHODS:We used a weight-...

journal_title：Neurosurgery

authors： Meehan WP 3rd,Zhang J,Mannix R,Whalen MJ

更新日期：2012-10-01 00:00:00

abstract：:A patient with air gun bullets in the 3rd ventricle associated with delayed ventricular hemorrhage is presented. Through an anterior transcallosal approach, the surgeon successfully removed the bullets without any significant permanent sequelae. ...

journal_title：Neurosurgery

authors： Kojima T,Waga S,Kubo Y,Shimizu T

更新日期：1987-02-01 00:00:00

abstract：:Evidence has accumulated that indicates that laminectomy with or without radiotherapy is not necessarily the best mode of treatment for all cases of spinal cord compression of malignant pathogenesis. Success is limited, and there is a high risk of adverse neurological developments, particularly where there is anterior...

journal_title：Neurosurgery

authors： Moore AJ,Uttley D

更新日期：1989-05-01 00:00:00

abstract：BACKGROUND:Stereotactic radiosurgery (SRS) is an effective option in the management of brain metastases, offering improved overall survival to whole-brain radiation therapy (WBRT). However, given the need for active surveillance and the possibility of repeated interventions for local/distant brain recurrences, the bala...

journal_title：Neurosurgery

authors： Warsi NM,Karmur BS,Brar K,Moraes FY,Tsang DS,Laperriere N,Kondziolka D,Mansouri A

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Multiple nationwide outcome registries are utilized for quality benchmarking between institutions and individual surgeons. OBJECTIVE:To evaluate whether nationwide quality of care programs in the United Kingdom and United States can measure differences in neurosurgical quality. METHODS:This prospective obs...

journal_title：Neurosurgery

authors： Reponen E,Tuominen H,Korja M

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVE:The statement that intracranial meningiomas are cleavable tumors has to be seriously questioned from a surgical standpoint. The purpose of this study was 1) to analyze the operative reports of a personal series of meningiomas to evaluate the percentages of the tumors that could be dissected by passing in the ...

journal_title：Neurosurgery

authors： Sindou MP,Alaywan M

更新日期：1998-03-01 00:00:00

abstract：:Three patients, ages 69, 67, and 74 years, respectively, underwent surgical removal of cystic cerebellar astrocytomas. All three had past histories pointing to the existence of a cerebellar lesion for many decades prior to surgery: Patient 1 had had nystagmus on lateral gaze on the side of the tumor since early childh...

journal_title：Neurosurgery

authors： Kepes JJ,Whittaker CK,Watson K,Morantz RA,Millett R,Clough CA,Oxley DK

更新日期：1989-08-01 00:00:00

abstract：OBJECTIVE:To analyze the possible role of the cerebellum in the modulation of cortical motor output associated with repetitive electrical stimulation of the sciatic nerve in the rat. METHODS:A sustained somatosensory stimulation induces an increase in the intensity of the response of the rodent motor cortex. Wistar ra...

journal_title：Neurosurgery

authors： Oulad Ben Taib N,Manto M,Laute MA,Brotchi J

更新日期：2005-04-01 00:00:00

abstract：:A case of hemangioblastoma of the right radial nerve is presented. Hemangioblastomas are rare vascular neoplasms characteristically associated with the Von Hippel-Lindau syndrome, in which they are found in the retina, the posterior fossa, and, less often, the spinal cord. Thought of as primary central nervous system ...

journal_title：Neurosurgery

authors： Brodkey JA,Buchignani JA,O'Brien TF

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Heat transfer from bipolar tips to adjacent tissue presents a risk of thermal injury during spine surgery. OBJECTIVE:The present study was designed to determine wither bipolar forceps using a novel heat pipe thermal regulation technology resulted in decreased collateral thermal injury of adjacent tissue com...

journal_title：Neurosurgery

authors： Elliott-Lewis EW,Jolette J,Ramos J,Benzel EC

更新日期：2010-07-01 00:00:00

abstract：:A compound of methylcellulose-silicone expanding progressively over a 1-week period by moisture absorption was implanted in the midthoracic epidural space of 17 Sprague Dawley adult rats. When the animals became paraplegic 6.3 +/- 1.6 days later, they were randomized into three groups: untreated control (n = 5), high ...

journal_title：Neurosurgery

authors： Delattre JY,Arbit E,Rosenblum MK,Thaler HT,Lau N,Galicich JH,Posner JB

更新日期：1988-06-01 00:00:00

abstract：BACKGROUND:One response to randomized trials like the International Subarachnoid Aneurysm Trial has been to adopt a "coil first" policy, whereby all aneurysms be considered for coiling, reserving surgery for unfavorable aneurysms or failed attempts. Surgical results with middle cerebral artery (MCA) aneurysms have been...

journal_title：Neurosurgery

authors： Rodríguez-Hernández A,Sughrue ME,Akhavan S,Habdank-Kolaczkowski J,Lawton MT

更新日期：2013-03-01 00:00:00

abstract：:Syringomyelia, once regarded as a degenerative disease of adults, is now recognized to be a disorder usually associated with the Chiari malformation and occurring in patients of all ages. We have reviewed 47 patients with syringomyelia treated on the Neurosurgical Service at the Hospital for Sick Children during the y...

journal_title：Neurosurgery

authors： Hoffman HJ,Neill J,Crone KR,Hendrick EB,Humphreys RP

更新日期：1987-09-01 00:00:00

abstract：OBJECTIVE:We report the long-term follow-up of 31 patients with cavernous sinus meningiomas who were treated either with surgery and radiotherapy (RT) or with RT alone. This retrospective review was undertaken to compare long-term efficacy and morbidity of RT with or without previous surgery versus complete, aggressive...

journal_title：Neurosurgery

authors： Dufour H,Muracciole X,Métellus P,Régis J,Chinot O,Grisoli F

更新日期：2001-02-01 00:00:00

abstract：OBJECTIVE:Balancing the benefits of extensive tumor resection with the consequence of potential postoperative deficits remains a challenge in malignant astrocytoma surgery. Although studies have suggested that increasing extent of resection may benefit survival, the effect of new postoperative deficits on survival rema...

journal_title：Neurosurgery

authors： McGirt MJ,Mukherjee D,Chaichana KL,Than KD,Weingart JD,Quinones-Hinojosa A

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:Anterior clinoidal meningiomas (ACMs) are a subgroup of meningiomas accounting for less than 10% of supratentorial meningiomas. OBJECTIVE:To assess the reliability and safeness of the lateral supraorbital approach (LSO) to remove ACMs. METHODS:Between September 1997 and October 2009, a total of 73 ACM pati...

journal_title：Neurosurgery

authors： Romani R,Laakso A,Kangasniemi M,Lehecka M,Hernesniemi J

更新日期：2011-06-01 00:00:00