Subacute pancerebellar syndrome associated with systemic lupus erythematosus.

Abstract:

:A pancerebellar syndrome of subacute progression associated with cerebellar atrophy is highly suggestive of a paraneoplastic cerebellar degeneration (PCD). We describe a 27-year-old woman with systemic lupus erythematosus (SLE) that presented with a subacute pancerebellar syndrome. Serum and CSF anti-Yo, anti-Hu and anti-Ri antibodies were not found neither in blood, nor in CSF. Brain MRI showed a cerebellar atrophy. The cerebellar ataxia improved markedly following corticosteroids administration. This case probably demonstrates that an antineuronal antibody negative subacute cerebellar disease may not only be a manifestation of paraneoplastic disease, but that it can also be associated with SLE.

journal_name

Clin Neurol Neurosurg

authors

Manto MU,Rondeaux P,Jacquy J,Hildebrand JG

doi

10.1016/0303-8467(96)00013-3

subject

Has Abstract

pub_date

1996-05-01 00:00:00

pages

157-60

issue

2

eissn

0303-8467

issn

1872-6968

pii

0303846796000133

journal_volume

98

pub_type

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