A piroxicam derivative partly effective in chronic paroxysmal hemicrania and hemicrania continua.

abstract：OBJECTIVE:Presentation of pooled analysis of safety data for fremanezumab in patients with chronic (CM) or episodic migraine (EM) from 4 placebo-controlled phase 2b and phase 3 studies. BACKGROUND:There is a need for an effective, safe, and well-tolerated preventive therapy that specifically targets the pathophysiolog...

journal_title：Headache

authors： Silberstein SD,McAllister P,Ning X,Faulhaber N,Lang N,Yeung P,Schiemann J,Aycardi E,Cohen JM,Janka L,Yang R

更新日期：2019-06-01 00:00:00

abstract：OBJECTIVE AND BACKGROUND:Pupillometric investigations into migraine have suggested that an autonomic disturbance is part of the pathogenesis of that condition. This observation is controversial, however, which may reflect that the putative sympathetic hypofunction is either subtle or transient. In this study, we assess...

journal_title：Headache

authors： Cambron M,Maertens H,Paemeleire K,Crevits L

更新日期：2014-04-01 00:00:00

abstract：:Over the past few years, sports-related concussion has received significant media attention making it one of the most, if not highest profile neurological disorder. Thirty-one states now have passed sports concussion laws, with 14 states pending legislation. Most concussions are managed by primary care physicians, ie,...

journal_title：Headache

authors： Conidi FX

更新日期：2012-05-01 00:00:00

abstract：:Head pain is the fifth most common reason for emergency department (ED) visits. It is second only to focal weakness as the most common reason for neurological consultation in the ED. This manuscript reviews how patients with migraine, the most common primary headache disorder for which patients seek medical treatment,...

journal_title：Headache

authors： Minen MT,Tanev K,Friedman BW

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Personality traits (especially neuroticism) and childhood maltreatment have been independently related to many negative health outcomes later in life, including migraine. Studies have also shown the association between childhood maltreatment and maladaptive personality traits. The mediating role of personali...

journal_title：Headache

authors： Karmakar M,Elhai JD,Amialchuk AA,Tietjen GE

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:In previous studies, pregnancy has been associated with less headache, but the influence of parity on this association is largely unknown. OBJECTIVES:To examine the prevalence of headache and migraine among pregnant women, and explore the relation of headache to parity in a large, population-based study. M...

journal_title：Headache

authors： Aegidius K,Zwart JA,Hagen K,Stovner L

更新日期：2009-06-01 00:00:00

abstract：OBJECTIVE:To look at the smoking history of migraine patients and to determine if a history of cigarette smoking is associated with the development of cranial autonomic symptoms with migraine headaches. BACKGROUND:It has recently been noted that a significant number of migraine patients may develop autonomic symptoms ...

journal_title：Headache

authors： Rozen TD

更新日期：2011-01-01 00:00:00

abstract：:Two cases of baroreflex failure presented with tension-type/exertional headache. The usefulness of noninvasive physiological tests in diagnosing baroreflex failure and the role of baroreceptors in trigeminal nociception are discussed. ...

journal_title：Headache

authors： Khurana RK

更新日期：2006-07-01 00:00:00

abstract：:This study examined the relationship between the menstrual cycle, the stress process, and migraines. Women migraineurs (N = 12) and a matched control sample (N = 12) completed a set of questionnaires assessing stress, appraisal, and coping at premenses, menses, and ovulation. In addition, migraineurs completed a month...

journal_title：Headache

authors： Holm JE,Bury L,Suda KT

更新日期：1996-10-01 00:00:00

abstract：OBJECTIVE:To investigate the influence of different pharmacological treatments on the intensity dependence of auditory evoked cortical potentials in migraineurs. BACKGROUND:Between attacks, patients with migraine show abnormalities in cortical information processing and decreased brain mitochondrial energy reserve. Bo...

journal_title：Headache

authors： Sándor PS,Afra J,Ambrosini A,Schoenen J

更新日期：2000-01-01 00:00:00

abstract：:The ideal migraine medication would provide rapid “one and done” treatment of migraine for all sufferers. Unfortunately, no such intervention is available. While most people respond to triptans or DHE, some will need to combine these with an NSAID, or will choose to use an NSAID alone because of personal preference or...

journal_title：Headache

authors： Tepper D

更新日期：2014-11-01 00:00:00

abstract：:Eighty-eight children and adolescents were prospectively evaluated at eight specialty clinics comparing the diagnostic criteria of the International Headache Society (IHS) and the proposed revised (IHS-R) classification to the clinical diagnosis. The proposed revisions to the IHS classification for pediatric migraine ...

journal_title：Headache

authors： Winner P,Wasiewski W,Gladstein J,Linder S

更新日期：1997-10-01 00:00:00

abstract：BACKGROUND:Despite the expanding therapeutic armamentarium, many people with episodic migraine (EM) have unmet acute treatment needs. OBJECTIVE:To determine the relative frequency of prespecified types of "unmet treatment needs" in persons with EM in a US population-based sample. METHODS:Eligible participants complet...

journal_title：Headache

authors： Lipton RB,Buse DC,Serrano D,Holland S,Reed ML

更新日期：2013-09-01 00:00:00

abstract：:The aim of this study was to clarify a possible relationship between pollution and worsening of headache in the industrial city of Turin. From October 1992 to June 1993, we examined a group of 32 patients suffering from various headache types. During these months, they kept a daily record of their headaches and associ...

journal_title：Headache

authors： Nattero G,Enrico A

更新日期：1996-04-01 00:00:00

abstract：:Genetic mutations of sporadic hemiplegic migraine (SHM) are mostly unknown. SHM pathophysiology relies on cortical spreading depression (CSD), which might be responsible for ischemic brain infarction. Cystic fibrosis (CF) is caused by a monogenic mutation of the chlorine transmembrane conductance regulator (CFTR), pos...

journal_title：Headache

authors： Mancini V,Mastria G,Frantellizzi V,Troiani P,Zampatti S,Carboni S,Giardina E,Campopiano R,Gambardella S,Turchi F,Petolicchio B,Toscano M,Liberatore M,Viganò A,Di Piero V

更新日期：2019-02-01 00:00:00

abstract：OBJECTIVES:The aim of our study is to determine the prevalence of migraine in Provincial Center of Edirne. METHODS:A systematic random sample of 386 inhabitants over 14 years old were interviewed face to face. Diagnosis of migraine was based on the International Headache Society (IHS) classification. RESULTS:Migraine...

journal_title：Headache

authors： Celik Y,Ekuklu G,Tokuç B,Utku U

更新日期：2005-01-01 00:00:00

abstract：:A questionnaire study on headaches, using a door-to-door survey, was carried out in a representative sample of the general Greek population, including 1737 men and 1764 women, from 15 to 75 years of age. The parameters evaluated included age, sex, education, socioeconomic status, region of domicile, frequency of heada...

journal_title：Headache

authors： Mitsikostas DD,Tsaklakidou D,Athanasiadis N,Thomas A

更新日期：1996-03-01 00:00:00

abstract：OBJECTIVE:To compare the efficacy of mouth-dispersible aspirin 900 mg and placebo in the treatment of migraine. BACKGROUND:Aspirin is widely accepted as an effective therapy for migraine. Previous studies have indicated that gastric stasis and delayed gastric emptying, which occur during migraine attacks, delay aspiri...

journal_title：Headache

authors： MacGregor EA,Dowson A,Davies PT

更新日期：2002-04-01 00:00:00

abstract：PURPOSE:Migraine is an exclusively human chronic disorder with ictal manifestations characterized by a multifaceted clinical complexity pointing to a cerebral cortical involvement. The present review is aimed to cover the clinical, neuroimaging, and neurophysiological literature on the role of the cerebral cortex in mi...

journal_title：Headache

authors： Barbanti P,Brighina F,Egeo G,Di Stefano V,Silvestro M,Russo A

更新日期：2020-10-01 00:00:00

abstract：:Traditionally, episodic primary headache disorders are characterized by a return of preheadache (normal) neurologic function between episodes of headache. In contrast, patients with chronic headache often do not return to normal neurologic function between headache attacks. This article proposes that the evolution fro...

journal_title：Headache

authors： Cady RK,Schreiber CP,Farmer KU

更新日期：2004-05-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy and safety of venlafaxine in the prophylaxis of migraine. BACKGROUND:The efficacy of venlafaxine, which is selectively effective on the serotonergic and noradrenergic mechanisms, on various headaches and chronic pain syndromes has been demonstrated. To our knowledge, this is the firs...

journal_title：Headache

authors： Ozyalcin SN,Talu GK,Kiziltan E,Yucel B,Ertas M,Disci R

更新日期：2005-02-01 00:00:00

abstract：OBJECTIVE:To compare, using a within-woman analysis, the severity, duration, and relapse of menstrual vs nonmenstrual episodes of migraine during treatment with usual migraine therapy. BACKGROUND:Studies comparing the clinical characteristics of menstrual and nonmenstrual migraine attacks have yielded conflicting resu...

journal_title：Headache

authors： MacGregor EA,Victor TW,Hu X,Xiang Q,Puenpatom RA,Chen W,Campbell JC

更新日期：2010-04-01 00:00:00

abstract：:More than 60 years ago Aristides Leão coined the term spreading depression (SD) to describe a transient "depression" of electrocorticographic activity that lasts up to several minutes and slowly "spreads" in all directions in cortex by way of gray matter contiguity.(1) Today we know that SD is an intrinsic electrophys...

journal_title：Headache

authors： Ayata C

更新日期：2010-04-01 00:00:00

abstract：OBJECTIVE:To evaluate the long-term tolerability of telcagepant for acute treatment of intermittent migraine attacks. Background.- Telcagepant is a calcitonin gene-related peptide (CGRP) receptor antagonist being investigated for the acute treatment of migraine. METHODS:Migraine patients were randomized 2:1 to double-...

journal_title：Headache

authors： Connor KM,Aurora SK,Loeys T,Ashina M,Jones C,Giezek H,Massaad R,Williams-Diaz A,Lines C,Ho TW

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:A hallmark of migraine is photophobia. In mice, photophobia-like behavior is induced by calcitonin gene-related peptide (CGRP), a neuropeptide known to be a key player in migraine. In this study, we sought to identify sites within the brain from which CGRP could induce photophobia. DESIGN:We focused on the p...

journal_title：Headache

authors： Sowers LP,Wang M,Rea BJ,Taugher RJ,Kuburas A,Kim Y,Wemmie JA,Walker CS,Hay DL,Russo AF

更新日期：2020-10-01 00:00:00

abstract：:We studied 11 patients undergoing a routine lumbar puncture to determine if there were cerebrospinal fluid leaks at the puncture site and whether the maximum volume of leakage correlates with a lumbar puncture headache. Patients completed a headache questionnaire before and after the lumbar puncture. Limited magnetic ...

journal_title：Headache

authors： Iqbal J,Davis LE,Orrison WW Jr

更新日期：1995-07-01 00:00:00

abstract：BACKGROUND:Recent research has shown that affective changes associated with the menstrual cycle may follow diverse patterns, including a classic premenstrual syndrome pattern, as well as the mirror opposite pattern, referred to as a mid-cycle pattern. OBJECTIVE:Test for the presence of a mid-cycle pattern of headaches...

journal_title：Headache

authors： Kiesner J,Martin VT

更新日期：2013-06-01 00:00:00

abstract：:Many investigators have described olfactory dysfunction among migraineurs. Olfactory stimuli can precipitate migraine, and olfactory hallucinations can occur as auras of migraines or as part of the symptom complex. Despite many reports linking olfactory phenomena and migraine, no evaluations of the olfactory abilities...

journal_title：Headache

authors： Hirsch AR

更新日期：1992-05-01 00:00:00

abstract：:Seventeen patients with migraine headaches, occurring at least twice a month, were successfully treated with an ACE inhibitor for prophylaxis. Most were given enalapril, some used lisinopril. Duration of treatment ranged from 3 months to 3 years. Side effects were generally not noted. Cough occurred in four patients. ...

journal_title：Headache

authors： Bender WI

更新日期：1995-09-01 00:00:00

abstract：OBJECTIVE:To address the need for a rigorous, direct comparison of prescription and over-the-counter (OTC) migraine drugs and to expand the database on early treatment of migraine. BACKGROUND:Most people who experience migraine use OTC medications to treat their symptoms, but no head-to-head clinical trials comparing ...

journal_title：Headache

authors： Goldstein J,Silberstein SD,Saper JR,Elkind AH,Smith TR,Gallagher RM,Battikha JP,Hoffman H,Baggish J

更新日期：2005-09-01 00:00:00