Lumbar disc degeneration and atherosclerosis of the abdominal aorta.

Abstract:

STUDY DESIGN:This study analyzed the relationship of disc degeneration to atherosclerotic changes in the abdominal aorta and stenosis of the ostia of the lumbar and middle sacral arteries, 86 plain radiographs of lumbosacral spines, and the corresponding abdominal aortas were evaluated in connection with routine autopsy. RESULTS:Disc degeneration, advanced atherosclerotic manifestations, and stenosis of the ostia of the lumbar and middle sacral arteries all increased with age (P < 0.001). After partial rank correlation analysis, keeping the effect of age constant, there was still a statistically significant association between the grade of disc degeneration and stenosis of the ostia of the arteries supplying the disc. The association was stronger at upper lumbar levels (0.001 < P < 0.01) than at lower ones (0.01 < P < 0.05). Furthermore, with complicated lesions in the abdominal aorta, disc degeneration at all lumbar levels increased. CONCLUSIONS:Atherosclerosis in the abdominal aorta and especially stenosis of the ostia of segmental arteries may play a part in lumbar disc degeneration.

journal_name

Spine (Phila Pa 1976)

journal_title

Spine

authors

Kauppila LI,Penttilä A,Karhunen PJ,Lalu K,Hannikainen P

doi

10.1097/00007632-199404150-00010

subject

Has Abstract

pub_date

1994-04-15 00:00:00

pages

923-9

issue

8

eissn

0362-2436

issn

1528-1159

journal_volume

19

pub_type

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