[Low-flow anesthesia: isoflurane increment kinetics as a function of the rotatory circuit volume].

Abstract:

OBJECTIVE:Study of the increment of isoflurane volume concentration in two rotatory circuits having different capacity during low flow narcosis. DESIGN:Descriptive comparison of different halogenate concentration in circuits connected to two patient groups and evaluation of the significance of the observed differences. SETTING:Surgery theatres of a district Public Hospital. PATIENTS:16 female patients included in the same age, weight and body surface group, showing neither obstructive nor restrictive lung diseases. According to the surgical treatment used (abdominal or major gynecological surgery) the patients were then divided into two groups of 8 each. MEASUREMENTS AND MAIN RESULTS:After opening the halogenate nebulizer, dry measurement of the isoflurane concentration detected for 30 minutes in the inspiratory and expiratory circuit segment by means of monitors at pre-determined intervals, before abdominal or major gynecological surgery. Simultaneous measurement of isoflurane uptake by means of indirect methods (heart frequency, average arterial pressure, use of muscle relaxing agents). The analysis of the measured values showed higher isoflurane concentrations and a faster percent increase in the small circuit than in the big one (resp. 0.9% vs 0.71% in the inspiratory segment and 0.59% vs 0.4% in the expiratory one, with p < 0.005 and I.C. = 99.00%). CONCLUSIONS:This study demonstrates how the different kinetics of the isoflurane increment in the rotatory circuit is mainly related to the circuit volume. To eliminate the problems due to the "low compliance" of the small circuit (collection of toxic gases) and to the "high compliance" of the big circuit rotatory (awareness), circuits with varying volume might be introduced.

journal_name

Minerva Anestesiol

journal_title

Minerva anestesiologica

authors

Reverberi C,Orlandi MC

subject

Has Abstract

pub_date

1994-09-01 00:00:00

pages

451-6

issue

9

eissn

0375-9393

issn

1827-1596

journal_volume

60

pub_type

杂志文章
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    authors: Filloux B,Bedel A,Nseir S,Mathiaux J,Amadéo B,Clouzeau B,Pillot J,Saghi T,Vargas F,Hilbert G,Gruson D,Boyer A

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    doi:

    authors: Snyder-Ramos SA,Motsch J,Martin E,Böttiger BW

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    doi:

    authors: Astuto M,Disma N,Crimi E

    更新日期:2002-07-01 00:00:00

  • Comparison of the i-gel™ with the AuraGain™ laryngeal mask airways in patients with a simulated cervical immobilization: a randomized controlled trial.

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    authors: Hur M,Choi S,Row HS,Kim TK

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    doi:

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    更新日期:2003-06-01 00:00:00

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  • [Continuous intravenous infusion with patient-controlled anesthesia for postoperative analgesia in cesarean section: morphine versus buprenorphine].

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    更新日期:1980-03-01 00:00:00

  • [Mortality in pediatric anesthesia].

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  • Perioperative care of diabetic patient.

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