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Treatment of "obstructive" pain by endoscopic drainage in patients with pancreatic head carcinoma.

Abstract：

:Obstruction of the main pancreatic duct with secondary upstream ductal hypertension is one cause of pain in patients with pancreatic cancer. Pancreatic endoscopic stenting and decompression of the pancreatic duct have been effective in the treatment of pain secondary to chronic calcifying pancreatitis and in one case of pancreatic cancer. We describe eight patients with unresectable cancer of the pancreatic head associated with upstream dilatation of the pancreatic duct and severe pancreatic "obstructive"-type pain (correlation with meals and pain radiation to the back) in which a pancreatic stent was inserted across the neoplastic stricture. No mortality was associated with the procedure. All patients but one were free of pain within 48 hours after endoscopic pancreatic stenting, and all discontinued narcotics. Mean survival time was 165.5 days (range, 26 to 575 days). Six patients were still without symptoms, whereas two had a painful relapse a few days before death. No clinical evidence of pancreatic clogged stent was observed during follow-up. Endoscopic pancreatic drainage is a safe and effective way of controlling cancer pain in selected cases and should be considered as a further therapeutic option in these patients.

journal_name

Gastrointest Endosc

journal_title

Gastrointestinal endoscopy

authors

Costamagna G,Gabbrielli A,Mutignani M,Perri V,Crucitti F

doi

10.1016/s0016-5107(93)70263-1

subject

Has Abstract

pub_date

1993-11-01 00:00:00

pages

774-7

issue

6

eissn

0016-5107

issn

1097-6779

pii

S0016-5107(93)70263-1

journal_volume

39

pub_type

杂志文章

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