Effects of irradiation on the expression of the adhesion molecules (NCAM, ICAM-1) by glioma cell lines.

Abstract:

:The expression of the intercellular adhesion molecule-1 (ICAM-1) and neural cell adhesion molecule (NCAM) by glioma cell lines was investigated. The effects of interferon (IFN)-gamma or irradiation on the expression was also assessed. Two glioma cell lines showed more than 75% NCAM-positive cells. After treatment with IFN-gamma or irradiation, another three cell lines were induced to show more than 50% positive cells. Three glioma cell lines showed more than 50% ICAM-1-positive cells. After treatment with IFN-gamma, another two cell lines were induced to show more than 50% positive cells. After treatment with irradiation, one more cell line was induced to show more than 50% positive cells. ICAM-1 and NCAM expression by glioma cell lines is susceptible to modulation by IFN-gamma or irradiation.

authors

Yamanaka R,Tanaka R,Yoshida S

doi

10.2176/nmc.33.749

subject

Has Abstract

pub_date

1993-11-01 00:00:00

pages

749-52

issue

11

eissn

0470-8105

issn

1349-8029

pii

JST.Journalarchive/nmc1959/33.749

journal_volume

33

pub_type

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