The structural events associated with the attachment of complement components to cell membranes in reactive lysis.

Abstract:

:Electron microscopic study of the events occurring at the cell membrane during reactive lysis by complement, showed that a foliaceous particle was formed at the C5b-7 stage, that enlarged to a particle with a variable number of arms at the C5b-8 stage. Up to this point, no typical complement lesions were found. At the C5b-9 stages, the particles were completely converted to typical complement lesions, i.e. hollow cylinders projecting from the cell membrane and partly penetrating it. C5b-9 complexes assembled in the fluid phase did not show the typical structure of the lesions, but were amorphous masses of fibres.

journal_name

Immunology

journal_title

Immunology

authors

Dourmashkin RR

subject

Has Abstract

pub_date

1978-08-01 00:00:00

pages

205-12

issue

2

eissn

0019-2805

issn

1365-2567

journal_volume

35

pub_type

杂志文章