Acceleration of muscle re-innervation in rats by ganglioside treatment: an electromyographic study.

Abstract:

:The sciatic nerve in the right thigh was divided in 40 rats and the nerve stumps then sewn together with two microsutures. The treated animals, 20 rats, had daily subcutaneous administration of a bovine cortex ganglioside mixture. The controls, 20 rats, received the solvent alone. At 21 days after nerve division it was found that more treated rats than controls had regenerated nerve fibres capable of producing re-innervation potentials in the gastrocnemius muscle. This result supports the view that cortex gangliosides act to accelerate muscle re-innervation.

journal_name

Eur J Pharmacol

authors

Kleinebeckel D

doi

10.1016/0014-2999(82)90061-9

subject

Has Abstract

pub_date

1982-05-21 00:00:00

pages

243-5

issue

2-3

eissn

0014-2999

issn

1879-0712

pii

0014-2999(82)90061-9

journal_volume

80

pub_type

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