Abstract：
:The authors established the specificity, reliability, and precision of human erythrocyte insulin radioreceptor assay. On the basis of insulin binding, cell viability, and degree of hemolysis, heparin sodium was found to be a more suitable anticoagulant than sodium fluoride, ethylenediaminetetraacetic acid, sodium oxalate, or sodium citrate. In two sets of experiments carried out at 4°C and 23°C, human erythrocytes were stored as whole blood or isolated erythrocytes suspended in Tris-{4-(2-hydroxyethyl)-1-piperazine-ethanesulfonic acid} buffer. The effect of storage under these conditions was evaluated by erythrocytespecific insulin binding. Human erythrocytes can be stored for 72 hours at 4°C without any change in insulin binding, insulin receptor sites per cell, or average affinity constant at the empty sites. Isolated erythrocytes can also be stored in plasma for 72 hours or in buffer G for 24 hours at 4°C without any change in insulin binding. It is not advisable to store human erythrocytes in plasma or as whole blood for more than 24 hours at 23°. These findings are useful in preserving insulin receptor activity when storage of erythrocytes is unavoidable.
journal_name
J Natl Med Assocjournal_title
Journal of the National Medical Associationauthors
Gambhir KK,Nerurkar SG,Carter L,Brickler C,Giridhar Gsubject
Has Abstractpub_date
1983-05-01 00:00:00pages
503-7issue
5eissn
0027-9684issn
1943-4693journal_volume
75pub_type
杂志文章abstract：:There have been increasing rates of uninsured patients in the United States over the past few decades. Despite this growing problem, little progress has been made to decrease the rate of growth of uninsured patients or to provide affordable insurance coverage to those who are unable to maintain insurance coverage thro...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：2006-11-01 00:00:00
abstract：:Various cardiovascular complications are among the major causes of mortality in renal transplant recipients. The authors examined the cardiovascular findings from necropsy of 18 renal transplant patients. All but three of the patients showed one or more pathological abnormalities. Five patients exhibited severe corona...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1986-12-01 00:00:00
abstract：:In the past 2 years, cities have reported skyrocketing rates of violence, crime, and abusive behavior including intrafamilial homicides. Of the 1838 homicide deaths last year among teenagers between the ages of 15 and 19, 71% involved the use of a firearm. Among black males in the same age group, 82% of the deaths wer...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1992-06-01 00:00:00
abstract：:Although pulmonary tuberculosis has decreased, extra pulmonary tuberculosis has shown a relative increase in frequency during the past decade. This paper discusses three cases of extrapulmonary tuberculosis which presented with abdominal signs. The patients were completely evaluated and surgery was done, followed by a...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1978-02-01 00:00:00
abstract：BACKGROUND:Nigeria is one of the ten countries with the highest tuberculosis (TB) burden globally and is experiencing an increasing incidence of drug resistance. This study aimed to determine the prevalence of mycobacterium tuberculosis and rifampicin resistance (DR-TB) among patients screened at the TB clinic of a ter...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/j.jnma.2017.04.007
更新日期：2018-02-01 00:00:00
abstract：:This article reviews diagnosis and management of infants with diabetes. These infants present with signs and symptoms confused with other more common illnesses in this age group. A physician examining an ill-appearing dehydrated infant, without any obvious cause for the dehydration, should quickly screen the urine for...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章,评审
doi：
更新日期：1991-04-01 00:00:00
abstract：:Growth standards specific to black boys and girls are necessary because genetically determined patterns of growth in black children are significantly different from those of white children. Such standards have only recently become available, and they need further refinement. The required improvements include: (1) adju...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1980-10-01 00:00:00
abstract：AIMS OF THE STUDY:Type-2 diabetic patients have excessive cardiovascular mortality, primarily related to diabetic nephropathy. The extent of the morbidity due to nephropathy in type-2 diabetes mellitus has not been fully quantified in Nigeria. This study aims to quantify the prevalence of micro- and macrovascular compl...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：2003-11-01 00:00:00
abstract：:Chronic leg ulcers in sickle cell anemia occur mainly around the ankles. The prevalence is up to 75% in adults. These ulcers are painful and debilitating, yet medical treatment is unsuccessful. Surgical treatment consists of repeated skin grafting procedures, which eventually deplete the patient's available donor site...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1989-08-01 00:00:00
abstract：BACKGROUND:High sensitivity C-reactive protein (hsCRP) and Plasminogen Activator Inhibitor-1 (PAI-1) are recognised independent novel risk factors for cardiovascular disease. Few studies have assessed cardiovascular risk factors in patients with hyperglycaemic emergencies (HE), despite it being a major cause of death i...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/j.jnma.2019.12.004
更新日期：2020-02-01 00:00:00
abstract：:Students of African ancestry often share an experience of being a racialized minority in the context of the educational institution. Late Professor of Anthropology John Ogbu's Cultural-ecological Theory of Academic Disengagement is employed to describe the negative responses encountered by peers in the name of academi...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/j.jnma.2016.12.001
更新日期：2017-04-01 00:00:00
abstract：:Colorectal cancer causes significant morbidity and mortality in the United States. Recommendations for colorectal cancer screening have been developed. This study evaluated the colorectal cancer screening practices of African-American and white patients by internal medicine resident physicians. A retrospective chart r...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1999-09-01 00:00:00
abstract：:The latency period is an extremely important transition between the preschool years and adolescence. Normal ego functioning is described, especially cognition, socialization, motor development, and defensive functions. ...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1979-11-01 00:00:00
abstract：OBJECTIVE:To determine if a patient's degree of access to healthcare predicts his or her fund of knowledge about cardiovascular diseases. METHODS:Trained research associates at a public, urban emergency department in New York City administered cross-sectional surveys to selected patients from June 2005 to January 2007...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：2007-12-01 00:00:00
abstract：:In an effort to determine the impact of race on the stage of prostate cancer at presentation, the records of 2102 patients diagnosed in Chicago between 1985 and 1987 were reviewed. For each of three age groups (less than 65, 65 to 75, and greater than 75 years), blacks had a significantly (P less than .05) lower perce...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1991-12-01 00:00:00
abstract：OBJECTIVES:To assess the level and determinants of African-American physicians' employment in health maintenance organizations (HMOs), particularly early in their careers. METHODS:We analyzed data from the 1991 and 1996 Young Physicians Surveys to assess racial differences in the likelihood of HMO employment (n = 3,70...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：2006-08-01 00:00:00
abstract：:This study examines whether race is a significant determinant of the diagnoses of acute myocardial infarction or angina pectoris in patients with symptoms suggestive of acute cardiac ischemia. The study population was comprised of 3401 (34%) African-American and 6600 (66%) white patients who presented to emergency dep...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章,多中心研究
doi：
更新日期：1997-10-01 00:00:00
abstract：:Patient navigation has been widely implemented by cancer care programs across the United States. While activities of navigators have been described elsewhere, little has been documented regarding specific strategies used or challenges experienced by navigators from their own perspectives. We describe the experience of...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/s0027-9684(15)30412-0
更新日期：2011-08-01 00:00:00
abstract：:We have attempted to initiate a much needed constructive dialogue regarding the participation of African-American patients in clinical cancer research trials. It was our intent to provide a greater understanding of the historical context and evolving nature of clinical research trials pertaining to cancer. Some of the...
journal_title：Journal of the National Medical Association
pub_type： 社论
doi：
更新日期：1994-03-01 00:00:00
abstract：:Hepatocellular carcinoma (HCC) is emerging as a major problem in the United States, primarily due to the development of liver cancer in patients with cirrhosis secondary to the hepatitis C virus. The diagnosis of HCC in patients with underlying cirrhosis can be achieved at an early stage if appropriate diagnostic meas...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：2000-08-01 00:00:00
abstract：:The achievements of 19th century medical education, practice, literature, and science and their affect on 20th century medicine are reviewed. The contributions made by 19th century physicians to change medical education are described, as well as the social processes that influenced medicine and science in both centuri...
journal_title：Journal of the National Medical Association
pub_type： 历史文章,杂志文章
doi：
更新日期：1988-02-01 00:00:00
abstract：BACKGROUND:A study in the general population has shown a higher acute respiratory distress syndrome (ARDS) mortality among blacks. We studied whether black blunt-trauma patients experience different ARDS incidence, ARDS-associated mortality, or ARDS case fatality rates. METHODS:National Trauma Data Bank (NTDB) extract...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/s0027-9684(15)30700-8
更新日期：2010-10-01 00:00:00
abstract：OBJECTIVE:To discuss the complication of pneumothorax from alveolar rupture after transtracheal high-frequency jet ventilation and to present a case of pneumothorax, pneumomediastinum and pneumoperitoneum after jet ventilation coupled with use of the microdebrider. METHOD:Detailed case report. RESULTS:Unilateral pnue...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：2007-09-01 00:00:00
abstract：:The gastrointestinal tract is the largest lymphoid reservoir of the body and is subject to damage that compromises the cellular and humoral defense mechanism. With the increasing numbers of patients infected with the human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS), health-care practiti...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章,评审
doi：
更新日期：1994-05-01 00:00:00
abstract：PURPOSE:Respondent-driven sampling (RDS) was used to recruit four samples of Black and Latino men who have sex with men (MSM) in three metropolitan areas to measure HIV prevalence and sexual and drug use behaviors. We compared demographic and behavioral risk characteristics of participants across sites, assessed the ex...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/j.jnma.2015.12.009
更新日期：2016-02-01 00:00:00
abstract：:Strangulated right Richter's inguinal hernia of the cecum is relatively rare. A case of this unusual hernia was successfully managed with a wedge resection and closure of the infarcted bowel wall in conjunction with complementary tube cecostomy. The procedure is easy to perform and relatively safe and is therefore rec...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1982-07-01 00:00:00
abstract：:Presented here is an unusual case of extrinsic biliary obstruction due to a mass caused by xanthogranulomatous pyelonephritis, in itself a rare disease, of the right kidney. This phenomenon has not been described previously in the literature, and it should be brought to the attention of practitioners as another possib...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1982-06-01 00:00:00
abstract：:Detection of intra-abdominal abscesses by computed tomography (CT) has an estimated accuracy rate of greater than 90 percent. Features helpful in detecting these abscesses include extraluminal gas, the "rind" sign, airfluid interface, and low and high density areas. The author presents three cases to illustrate the us...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1985-08-01 00:00:00
abstract：:Retroperitoneal fibrosis secondary to carcinoma of the gallbladder has not been reported previously. Such a combination is reported and a review of the pertinent literature presented. ...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1989-09-01 00:00:00
abstract：:In sub-Saharan Africa, human immunodeficiency virus (HIV) and Mycobacterium tuberculosis (TB) are among the leading causes of morbidity and mortality. Sub-Saharan Africa has seen the woeful failure of World Health Organization (WHO) targets of detecting 70% of the infectious cases of tuberculosis and curing > or =85%....
journal_title：Journal of the National Medical Association
pub_type： 社论,评审
doi：
更新日期：2007-12-01 00:00:00
