Abstract：
BACKGROUND:Nigeria is one of the ten countries with the highest tuberculosis (TB) burden globally and is experiencing an increasing incidence of drug resistance. This study aimed to determine the prevalence of mycobacterium tuberculosis and rifampicin resistance (DR-TB) among patients screened at the TB clinic of a tertiary institution in Lagos, South-West, Nigeria. METHODS:A review of records of 840 patients with suspected drug-resistant TB was carried out from Gene Xpert test clinic register at a tertiary health facility from November 2013 to April 2015. The Data was analyzed with SPSS version 20, Chi square test was used to determine association between DR-TB and the factors examined and the level of significance was set at P < 0.05. RESULTS:MTB detection among all screened suspects was 43.3%. The prevalence of rifampicin resistance was 17.6% among patients that were investigated for DR-TB and this occurred more in the working age group (15-54 years) with male to female ratio of 1.8:1. However, only history of close contact with known DR-TB patient was associated with DR-TB (P < 0.01). CONCLUSION:The burden of DR-TB may be higher than previously thought. Drug resistance testing should be made more available to detect cases and thus control the emerging problem.
journal_name
J Natl Med Assocjournal_title
Journal of the National Medical Associationauthors
Kuyinu YA,Odugbemi BA,Salisu-Olatunji SO,Adepoju FO,Odusanya OOdoi
10.1016/j.jnma.2017.04.007subject
Has Abstractpub_date
2018-02-01 00:00:00pages
88-91issue
1eissn
0027-9684issn
1943-4693pii
S0027-9684(17)30014-7journal_volume
110pub_type
杂志文章abstract：:The health and well-being of all individuals, independent of race, ethnicity, or gender, is a significant public health concern. Despite many improvements in the status of minority health, African American males continue to have the highest age-adjusted mortality rate of any race-sex group in the United States. Such d...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/s0027-9684(15)30361-8
更新日期：2011-06-01 00:00:00
abstract：:An overview of psychiatric disorders seen in older patients is reviewed. Dementing illnesses are discussed. A specific method of assessing the patient with cognitive decline in a clear sensorium is presented. ...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1986-04-01 00:00:00
abstract：:A 31-year-old black man presented with bilateral multiple renal papillary adenocarcinomas. The patient had been maintained on captopril therapy for severe hypertension for three years. The possibility of drug-induced malignancy is discussed. ...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1984-11-01 00:00:00
abstract：:The author traces the history of theories of food digestion from the prescientific era to the chemical techniques of 19th century investigators. ...
journal_title：Journal of the National Medical Association
pub_type： 历史文章,杂志文章
doi：
更新日期：1987-11-01 00:00:00
abstract：:A day-long seminar was held at Wake Forest University School of Medicine to address barriers among ethnic minorities in cancer clinical trials and explore ways that individuals who design and conduct clinical trials could increase minority representation. Speakers addressed implications of under-representation of mino...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章,评审
doi：
更新日期：2002-01-01 00:00:00
abstract：BACKGROUND:It is commonly perceived that patients with sickle cell disease have increased hospital length of stay (LOS) because of mental health issues, including depression and drug-seeking behavior. However, the effect of mental and physical functional status on acute care resource use is unknown. OBJECTIVE:To asses...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/s0027-9684(15)30826-9
更新日期：2009-02-01 00:00:00
abstract：PURPOSE:To determine the factors associated with inadequate follow-up for abnormal Pap smears among a cohort of Boston women from urban academic clinics. METHODS:Subjects were women > 18 years with abnormal cervical cytology between February 1999 and April 2000. Inadequate follow-up was defined as lack of subsequent c...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：2003-09-01 00:00:00
abstract：:Diabetes is the leading cause of blindness, end-stage renal failure, non-traumatic limb amputations, and cardiovascular morbidity and mortality. The vast majority of patients with diabetes receive routine care from primary care providers who are not endocrinologists. Primary care providers, including internists, famil...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章,评审
doi：
更新日期：2002-07-01 00:00:00
abstract：OBJECTIVE:To identify social, behavioral and epidemiologic factors associated with HIV infection among HIV-infected and HIV-uninfected black women residing in North Carolina. DESIGN:A case-control study conducted in August 2004 in North Carolina. METHODS:Cases were 18-40-year-old women with HIV infections diagnosed f...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：2006-11-01 00:00:00
abstract：:The association among race, neighborhood socioeconomic status (SES), and chronic pain has not been well examined in older people. Clinical data was obtained from older adults (>50 years old) presenting to a tertiary care pain center. The relative roles of race and neighborhood SES on the chronic pain experienced in ol...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：2007-10-01 00:00:00
abstract：AIMS OF THE STUDY:Type-2 diabetic patients have excessive cardiovascular mortality, primarily related to diabetic nephropathy. The extent of the morbidity due to nephropathy in type-2 diabetes mellitus has not been fully quantified in Nigeria. This study aims to quantify the prevalence of micro- and macrovascular compl...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：2003-11-01 00:00:00
abstract：:Swainsonine, an indolizidine alkaloid with immunomodulatory activity, has been found to be effective in inhibiting metastatic dissemination and growth of primary tumors of both murine and human origins. The unique ability of swainsonine to exhibit antimetastatic, anti-proliferative, and immunomodulatory activity impar...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章,评审
doi：
更新日期：1989-10-01 00:00:00
abstract：:The treatment of patients with sickle cell disease and cholelithiasis is controversial. This retrospective study assesses the outcome of preoperative transfusion and timely cholecystectomy in symptomatic sickle cell disease patients. Fourteen patients who had undergone cholecystectomy were determined to have sickle ce...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1992-08-01 00:00:00
abstract：CONTEXT:The incidence of esophageal adenocarcinoma is rising and has surpassed squamous cell carcinoma. OBJECTIVE:To determine how the increasing incidence of esophageal adenocarcinoma alters the classic clinical presentation and the implications of these changes for diagnosis. DESIGN AND SETTING:A five-year retrospe...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：2007-06-01 00:00:00
abstract：BACKGROUND:African American adults achieve smaller amounts of weight loss than their white counterparts when exposed to the same intervention and are more likely to regain weight during long-term follow-up. OBJECTIVE:To identify perceived motivators, barriers, and facilitators to weight loss and behavior change among ...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/j.jnma.2017.01.006
更新日期：2017-07-01 00:00:00
abstract：:An eight-year-old black male with severe growth and mental retardation presented with massive myxedema, hyponatremia, and hypothermia. History of hypothyroidism was confirmed by laboratory investigation. The hypothyroidism appeared to be secondary to organic pituitary insufficiency due to diffuse brain damage. Appropr...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1980-07-01 00:00:00
abstract：:Women from Africa are a fast-growing population group in the United States; however, little is known about their breast cancer outcomes. There is minimal empirical data that describe the cancer practices, beliefs, and needs of African-born women. We conducted 2 focus groups with 20 African women to: (1) explore their ...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/s0027-9684(15)30553-8
更新日期：2010-06-01 00:00:00
abstract：:Caseous granulomatous lesions, consistent with tuberculosis, were found in the spleen in two of our renal transplant candidates. There was no clinical evidence of tuberculosis in either patient. Only one patient had a positive tuberculin skin test whose chest film showed hilar calcifications suggestive of healed granu...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1978-03-01 00:00:00
abstract：OBJECTIVE:To discuss the complication of pneumothorax from alveolar rupture after transtracheal high-frequency jet ventilation and to present a case of pneumothorax, pneumomediastinum and pneumoperitoneum after jet ventilation coupled with use of the microdebrider. METHOD:Detailed case report. RESULTS:Unilateral pnue...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：2007-09-01 00:00:00
abstract：:Organizational barriers play a key role in colorectal cancer (CRC) screening disparities in low-income minorities. This is a prospective, randomized trial to determine whether a patient navigator (PN) can help overcome the organizational barriers low-income minorities face in trying to obtain screening colonoscopy. Pa...
journal_title：Journal of the National Medical Association
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0027-9684(15)31240-2
更新日期：2008-03-01 00:00:00
abstract：:Renal medullary carcinoma (RMC) is a rare but highly aggressive neoplasm that primarily affects young African Americans with sickle cell trait. Most patients present with macroscopic hematuria and have metastases at diagnosis. Chemotherapy, biologics directed against the more common renal cell carcinomas and radiation...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/j.jnma.2016.08.006
更新日期：2017-04-01 00:00:00
abstract：:To minimize the incidence of postoperative infections in patients undergoing open-heart surgery, antibiotics should maintain tissue concentrations greater than the minimal inhibitory concentration (MIC) for potential pathogens (eg, Staphylococcus) for the duration of the operation. The ability of cefonicid, a new β-la...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1983-11-01 00:00:00
abstract：BACKGROUND:African Americans experience high rates of obesity and other chronic diseases, which may be related, in part, to diet. However, little is known about dietary patterns in this population, particularly from population-based data sources. METHODS:A cross-sectional analysis was conducted of 2,172 African-Americ...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：2004-12-01 00:00:00
abstract：:The personality of the therapist does influence the psychotherapeutic process. Given that therapists are human, they do, in fact, bring into the encounter their moral and cultural, and sometimes even racial, attitudes in spite of efforts to maintain objectivity and neutrality. Ignoring the impact of the therapist-clie...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1982-05-01 00:00:00
abstract：PURPOSE:The purpose of this review was to better understand possible social, economic, cultural, behavioral, and systems barriers to breast cancer screening among minority women. METHODS:Relevant manuscripts were identified through a MEDLINE/PubMed search for English-language literature from October 1971 through April...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章,评审
doi：10.1016/s0027-9684(15)30527-7
更新日期：2010-03-01 00:00:00
abstract：:The rare association of protease inhibitor deficiency (Pi(zz) genotype) in a black American with chronic, obstructive pulmonary disease due to asthmatic bronchitis, rather than basal pan lobular emphysema, is presented. The late onset of symptoms, despite environmental exposures, is also unusual in this homozygote, as...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1978-02-01 00:00:00
abstract：:This article presents data on total cholesterol (TC) determinations carried out in black patients of an inner-city neighborhood health center. In the pediatric group (under age 18), TC determinations were carried out only in over-weight children. In adults, they were performed routinely on all new admissions. During 1...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1994-07-01 00:00:00
abstract：:Colorectal cancer causes significant morbidity and mortality in the United States. African Americans are disproportionately affected by this malignancy. There is evidence to suggest that resident physicians inconsistently screen for colorectal cancer in African Americans, perhaps because of a deficiency in knowledge a...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：2007-09-01 00:00:00
abstract：BACKGROUND:This study presents black-white breast cancer statistics, tumor histology and receptor status, and treatment patterns for all ages and by age groups (< 40, 40-49, and > or = 50). METHODS:The study used data from the National Cancer Institute (NCI) Surveillance, Epidemiology and End Results (SEER) program fo...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/s0027-9684(15)31294-3
更新日期：2008-05-01 00:00:00
abstract：:Sixteen normal individuals and 100 hospital patients, all black, were tested for abnormal carcinoembryonic antigen (CEA) levels. Male and female subjects (smokers and non-smokers) were tested. The results of the tests are discussed. For normal subjects, the CEA values ranged from 0.0 ng/ml to 2.6 ng/ml. Among hospital...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1979-10-01 00:00:00
