Abstract:
:Eight patients were studied to determine the changes in pancuronium requirements during hypothermic cardiopulmonary bypass. They were anaesthetised with fentanyl as the principal agent, ventilated with oxygen and the neuromuscular junction was monitored using train-of-four stimulation. After a bolus dose of pancuronium an infusion was used to maintain the first twitch of the train-of-four at 5-15 per cent of control. Before bypass the mean pancuronium infusion rate was 0.52 (SD 0.16) micrograms/kg/min. There was a small, brief increase in requirement with the initiation of bypass to 0.62 (SD 0.38) micrograms/kg/min, which was followed by a decrease of more than 80 per cent during hypothermia to 0.08 (SD 0.03) micrograms/kg/min. Rewarming was associated with a rapid increase in requirement to 0.64 (SD 0.17) micrograms/kg/min, which decreased to 0.33 (SD 0.23) micrograms/kg/min when normothermia was re-established.
journal_name
Anaesth Intensive Carejournal_title
Anaesthesia and intensive careauthors
Futter ME,Whalley DG,Wynands JE,Bevan DRdoi
10.1177/0310057X8301100306subject
Has Abstractpub_date
1983-08-01 00:00:00pages
216-9issue
3eissn
0310-057Xissn
1448-0271journal_volume
11pub_type
杂志文章abstract::We tested the hypothesis that haemodynamic changes to intubation and postoperative pharyngolaryngeal morbidity are similar for blind intubating laryngeal mask (ILM)-guided compared with laryngoscope-guided tracheal intubation in adults with normal airways. We also compared intubation success rates and airway complicat...
journal_title:Anaesthesia and intensive care
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1177/0310057X0002800305
更新日期:2000-06-01 00:00:00
abstract::An inexpensive and convenient method of collecting waste gases from the open-tailed bag of a T-piece system is described. ...
journal_title:Anaesthesia and intensive care
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journal_title:Anaesthesia and intensive care
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journal_title:Anaesthesia and intensive care
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journal_title:Anaesthesia and intensive care
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journal_title:Anaesthesia and intensive care
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journal_title:Anaesthesia and intensive care
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更新日期:2004-06-01 00:00:00
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journal_title:Anaesthesia and intensive care
pub_type: 杂志文章
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journal_title:Anaesthesia and intensive care
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journal_title:Anaesthesia and intensive care
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journal_title:Anaesthesia and intensive care
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journal_title:Anaesthesia and intensive care
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journal_title:Anaesthesia and intensive care
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journal_title:Anaesthesia and intensive care
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journal_title:Anaesthesia and intensive care
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journal_title:Anaesthesia and intensive care
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journal_title:Anaesthesia and intensive care
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journal_title:Anaesthesia and intensive care
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