Abstract：
:The aim of this randomised controlled study was to compare continuous subcutaneous insulin infusion using an insulin pump with the traditional continuous intravenous infusion method for tight glycaemic control. Sixty patients admitted to our University Hospital medical intensive care unit with an initial blood glucose level over 6.1 mmol/l, were enrolled and randomised into two treatment groups: the subcutaneous insulin group received continuous subcutaneous insulin infusion and the intravenous group received insulin by traditional intravenous infusion with infusers. Three patients died in the first 24 hours and were excluded from the final analysis. Insulin therapy was administered to both groups according to the previously designed and used protocol in the department. The target glucose level was 4.4 to 6.1 mmol/l. There was no significant difference in mortality between the groups. However mean blood glucose level was found to be lower (6.56+/-0.82 mmol/l vs. 7.85+/-1.6 mmol/l, P=0.00055) in the subcutaneous insulin group. According to Vogelzang's hyperglycaemic index, better glycaemic control was achieved in the subcutaneous insulin group while there was no significant difference in terms of hypoglycaemic events. Daily insulin bolus and infusion requirements were also significantly lower in the subcutaneous insulin group. Despite the small number of patients involved in this study in a medical intensive care unit, strict blood glucose control using a subcutaneous insulin pump was achieved more efficiently than the traditional intravenous infusion method without increasing hypoglycaemic events.
journal_name
Anaesth Intensive Carejournal_title
Anaesthesia and intensive careauthors
Bodur HA,Saygili F,Saygili S,Doganay LH,Yesil Sdoi
10.1177/0310057X0803600421subject
Has Abstractpub_date
2008-07-01 00:00:00pages
520-7issue
4eissn
0310-057Xissn
1448-0271pii
20080024journal_volume
36pub_type
杂志文章,随机对照试验abstract：:A case of acute thyroid swelling is reported following intubation of a young woman with a pre-existing small goitre. The thyroid enlargement then distorted the airway, necessitating an emergency thyroidectomy. The application of cricoid pressure was believed to have caused the intrathyroidal bleeding and the complicat...
journal_title：Anaesthesia and intensive care
pub_type： 杂志文章
doi：10.1177/0310057X0303100415
更新日期：2003-08-01 00:00:00
abstract：:Predicting unexpected intensive care unit (ICU) re-admission and mortality after critical illness is difficult. This study assessed the associations between eosinopenia on the day of ICU discharge and outcomes after critical illness. This retrospective cohort study involved a total of 1446 critically ill patients who ...
journal_title：Anaesthesia and intensive care
pub_type： 杂志文章
doi：10.1177/0310057X1304100130
更新日期：2013-03-01 00:00:00
abstract：:Not many centres measure intracranial pressure during an endoscopic procedure. However, if the irrigation fluid during endoscopy is not simultaneously drained, then some rise in intracranial pressure can be anticipated. This study was carried out to measure and monitor changes in intracranial pressure during the irrig...
journal_title：Anaesthesia and intensive care
pub_type： 临床试验,杂志文章
doi：10.1177/0310057X0703500209
更新日期：2007-04-01 00:00:00
abstract：:Pethidine is the only member of the opioid family that has clinically important local anaesthetic activity in the dose range normally used for analgesia. Pethidine is unique as the only opioid in current use that is effective as the sole agent for spinal anaesthesia. In lower doses, intrathecal pethidine is also an ef...
journal_title：Anaesthesia and intensive care
pub_type： 杂志文章,评审
doi：10.1177/0310057X9802600202
更新日期：1998-04-01 00:00:00
abstract：:No specific prognostic model has been developed for patients readmitted to the intensive care unit (ICU) during the same hospitalisation. This study assesses the performance of the Acute Physiology and Chronic Health Evaluation (APACHE) II predicted mortality measured at the time of ICU readmission and whether incorpo...
journal_title：Anaesthesia and intensive care
pub_type： 杂志文章
doi：10.1177/0310057X0803600107
更新日期：2008-01-01 00:00:00
abstract：:Plasma osmolalities were measured in 100 normal, 100 general hospital and 100 intensive care patients, and compared with the osmolalities calculated from the plasma concentrations of sodium, potassium, glucose and urea, using five different published formulae. The mean osmolar gaps in the 100 consecutive intensive car...
journal_title：Anaesthesia and intensive care
pub_type： 杂志文章
doi：10.1177/0310057X8701500214
更新日期：1987-05-01 00:00:00
abstract：:Prolonged intermittent renal replacement therapy (PIRRT) is a recently defined acute modality for critically ill patients, and in theory combines the superior detoxification and haemodynamic stability of continuous renal replacement therapy (CRRT) with the operational convenience and low cost of intermittent haemodial...
journal_title：Anaesthesia and intensive care
pub_type： 杂志文章
doi：10.1177/0310057X1204000208
更新日期：2012-03-01 00:00:00
abstract：:The clinical effects of high-volume spinal anaesthesia with bupivacaine 0.125% were studied in 30 patients presenting for postpartum sterilisation. Group A, B and C patients received 6, 8 and 10 ml of bupivacaine 0.125% respectively. Onset, duration and regression of sensory block and motor blockade, haemodynamic para...
journal_title：Anaesthesia and intensive care
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1177/0310057X9202000407
更新日期：1992-11-01 00:00:00
abstract：:Costing data for intensive care admissions is important, not only for unit funding, but also for cost outcome analysis of new therapies. This paper presents an intensive care episode costing methodology using the example of a cost-benefit analysis of mask CPAP for severe cardiogenic pulmonary oedema (CPO). This analys...
journal_title：Anaesthesia and intensive care
pub_type： 杂志文章
doi：10.1177/0310057X9402200209
更新日期：1994-04-01 00:00:00
abstract：:We carried out an audit of needle cricothyroidotomy and transtracheal ventilation used during anaesthesia for elective endolaryngeal surgery. The data on 90 consecutive procedures was collected over two years. Patients were anaesthetized using a total intravenous technique. An intravenous cannula or Tuohy needle was p...
journal_title：Anaesthesia and intensive care
pub_type： 杂志文章
doi：10.1177/0310057X0002800112
更新日期：2000-02-01 00:00:00
abstract：:The transmuscular quadratus lumborum (TQL) block is one of the recently evolved myofascial blocks utilised in abdominal surgery. It involves injecting local anaesthetic into the fascial plane anterior to the thoracolumbar fascia. This block has previously been described with a transverse oblique paramedian approach at...
journal_title：Anaesthesia and intensive care
pub_type： 杂志文章
doi：10.1177/0310057X19839931
更新日期：2019-03-01 00:00:00
abstract：:The objective of this study was to assess the outcome of Jehovah's Witness (JW) patients admitted to a major Australasian ICU and to review the literature regarding the management of critically ill Jehovah's Witness patients. All Jehovah's Witness patients admitted to the ICU between January 1999 and September 2003 we...
journal_title：Anaesthesia and intensive care
pub_type： 杂志文章
doi：10.1177/0310057X0403200611
更新日期：2004-12-01 00:00:00
abstract：:Three cases of severe anaphylaxis to gallamine triethiodide are described. All reported cases of anaphylaxis to gallamine have occurred in women, and all the confirmed cases in Australasia. There is evidnece that women may be exposed to some substance which leaves them sensitive to gallamine triethiodide. ...
journal_title：Anaesthesia and intensive care
pub_type： 杂志文章
doi：10.1177/0310057X7800600110
更新日期：1978-02-01 00:00:00
abstract：:In order to introduce the technique of epidural narcotics for pain relief in Papua New Guinea, fifty patients were given low doses of epidural morphine and thereupon the quality of analgesia and morbidity evaluated. The lowest effective epidural morphine dose was determined by considering the patient's characteristics...
journal_title：Anaesthesia and intensive care
pub_type： 杂志文章
doi：10.1177/0310057X8901700315
更新日期：1989-08-01 00:00:00
abstract：:We tested the hypothesis that haemodynamic changes to intubation and postoperative pharyngolaryngeal morbidity are similar for blind intubating laryngeal mask (ILM)-guided compared with laryngoscope-guided tracheal intubation in adults with normal airways. We also compared intubation success rates and airway complicat...
journal_title：Anaesthesia and intensive care
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1177/0310057X0002800305
更新日期：2000-06-01 00:00:00
abstract：:Retro-orbital tumour was the cause of headache and neuropathic facial pain in a 31-year-old pregnant woman. The diagnosis had been overlooked as a result of a long history of migraine. There was exacerbation of the pain throughout the pregnancy, particularly in the third trimester. Pharmacological agents commonly used...
journal_title：Anaesthesia and intensive care
pub_type： 杂志文章
doi：10.1177/0310057X0102900310
更新日期：2001-06-01 00:00:00
abstract：:The use of summary answers to a question as an aid to introducing and guiding a tutorial is described using as an example a question about the physiological changes associated with pyrexia. It illustrates a method that involves all the students and develops a logical comprehensive answer that can also be helpful to st...
journal_title：Anaesthesia and intensive care
pub_type： 杂志文章
doi：10.1177/0310057X7600400412
更新日期：1976-11-01 00:00:00
abstract：:The efficacy of the McCoy laryngoscope, external laryngeal pressure, and their combination to improve the laryngoscopic view was evaluated in 219 patients and compared with the Macintosh laryngoscope. An experienced laryngoscopist performed laryngoscopy twice using the Macintosh laryngoscope and the McCoy laryngoscope...
journal_title：Anaesthesia and intensive care
pub_type： 临床试验,杂志文章
doi：10.1177/0310057X0002800509
更新日期：2000-10-01 00:00:00
abstract：:Amethocaine has recently been introduced as a topical local anaesthetic preparation. Following sporadic reports of severe local adverse effects, we conducted an audit of 372 children attending our hospital for day surgery. We conclude that 4% amethocaine cream is a safe and effective topical anaesthetic and that the i...
journal_title：Anaesthesia and intensive care
pub_type： 杂志文章
doi：10.1177/0310057X9802600316
更新日期：1998-06-01 00:00:00
abstract：:Fluid administration has been reported to be associated with an increased risk of acute kidney injury (AKI). We assessed whether, after correction for fluid balance, amount and chloride content of fluids administered have an independent association with AKI. We performed an observational study in patients after major ...
journal_title：Anaesthesia and intensive care
pub_type： 杂志文章
doi：10.1177/0310057X1804600112
更新日期：2018-01-01 00:00:00
abstract：:A 47-year-old woman with Cushing's syndrome suffered a severe anaphylactic reaction on induction of anaesthesia, resulting in circulatory arrest. A spontaneous cardiac output appeared after 25 minutes of chest compression and she regained consciousness three hours later, with no neurological deficit. A Bispectral Inde...
journal_title：Anaesthesia and intensive care
pub_type： 杂志文章
doi：10.1177/0310057X0102900518
更新日期：2001-10-01 00:00:00
abstract：:A review of the medical records from two public hospitals in Sydney was undertaken to determine the incidence of this uncommon complication. Twenty-seven cases of uterine rupture were reported out of 31,115 deliveries with an incidence of 0.086% (versus 0.05% in the current literature). The incidence associated with p...
journal_title：Anaesthesia and intensive care
pub_type： 杂志文章
doi：10.1177/0310057X9602400612
更新日期：1996-12-01 00:00:00
abstract：:Little is known about the experiences of patients with severe comorbidity discharged from Intensive Care Units (ICUs). This project aimed to determine the effects of an ICU stay for patients with severe comorbidity by comparing 1) quality of life (QOL), 2) the symptom profile of hospital survivors and 3) health servic...
journal_title：Anaesthesia and intensive care
pub_type： 杂志文章
doi：10.1177/0310057X1504300214
更新日期：2015-03-01 00:00:00
abstract：:An elevated serum lactate level is associated with morbidity and mortality in patients with severe sepsis and septic shock. In patients with hepatic dysfunction, however an elevated serum lactate level may be due to either impaired lactate clearance or excessive production. Thus, we evaluated whether the initial serum...
journal_title：Anaesthesia and intensive care
pub_type： 杂志文章
doi：10.1177/0310057X1103900510
更新日期：2011-09-01 00:00:00
abstract：:The effects of three different physiotherapy techniques on arterial oxygen tensions and A-aO2 gradients were evaluated in 17 patients subjected to mechanical ventilation. No significant changes were detected and the clinical significance of these findings, which contrast with those of other investigators, is discussed...
journal_title：Anaesthesia and intensive care
pub_type： 杂志文章
doi：10.1177/0310057X7500300309
更新日期：1975-08-01 00:00:00
abstract：:Recent studies which suggest the existence of an endogenous neural substrate of pain inhibition are reviewed. Electrical stimulation of some areas of the medial brain stem in laboratory rats has produced a dramatic degree of analgesia. Such stimulation-produced analgesia is partially blocked by an opiate antagonist dr...
journal_title：Anaesthesia and intensive care
pub_type： 杂志文章
doi：10.1177/0310057X8201000209
更新日期：1982-05-01 00:00:00
abstract：:A study was undertaken to determine the time constants of elimination and effect compartment equilibration of suxamethonium and for the slope exponent of the Hill equation. Twelve patients were anaesthetized with thiopentone, fentanyl, and isoflurane in nitrous oxide and oxygen. After allowing conditions to become sta...
journal_title：Anaesthesia and intensive care
pub_type： 杂志文章
doi：10.1177/0310057X9702500312
更新日期：1997-06-01 00:00:00
abstract：:The management of anaesthesia and outcome of 75 treatments in 52 patients are discussed. Total intravenous anaesthetic techniques were used with venturi ventilation via a rigid bronchoscope. A number of complications occurred, but there was no death or major surgical complication. All complications except one were app...
journal_title：Anaesthesia and intensive care
pub_type： 杂志文章
doi：10.1177/0310057X9001800112
更新日期：1990-02-01 00:00:00
abstract：:This study was undertaken to identify factors influencing outcome in elderly patients operated for hip fracture. In particular, this study examined factors related to mortality at least 30 months post-fracture. Hospital records and death registrations were analysed for 463 patients aged 60 or more years treated for hi...
journal_title：Anaesthesia and intensive care
pub_type： 杂志文章
doi：10.1177/0310057X0503300608
更新日期：2005-12-01 00:00:00
abstract：:A 74-year-old man with cardiac failure and renal impairment was admitted to the cardiothoracic intensive care unit with metformin-induced lactic acidosis and shock. He was successfully treated with high-dose (80 ml/kg/hour) continuous venovenous haemodiafiltration. Lactic acidosis is a known complication of metformin ...
journal_title：Anaesthesia and intensive care
pub_type： 杂志文章
doi：10.1177/0310057X0903700520
更新日期：2009-09-01 00:00:00
