Intrathecal pethidine: pharmacology and clinical applications.

Abstract:

:Pethidine is the only member of the opioid family that has clinically important local anaesthetic activity in the dose range normally used for analgesia. Pethidine is unique as the only opioid in current use that is effective as the sole agent for spinal anaesthesia. In lower doses, intrathecal pethidine is also an effective analgesic for treating pain in labour. This paper reviews the pharmacology of intrathecal pethidine and clinical experience reported to date. Articles reviewed include those identified by a Medline search using keywords "intrathecal" or "spinal anaesthesia/ anesthesia" and "pethidine" or "meperidine". Reference lists from identified papers were scrutinized to identify further relevant articles.

journal_name

Anaesth Intensive Care

authors

Ngan Kee WD

doi

10.1177/0310057X9802600202

subject

Has Abstract

pub_date

1998-04-01 00:00:00

pages

137-46

issue

2

eissn

0310-057X

issn

1448-0271

pii

1997349

journal_volume

26

pub_type

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