Alleged allergy to local anaesthetics.

Abstract:

:The aim of this study was to determine the incidence of true local anaesthetic allergy in patients with an alleged history of local anaesthetic allergy and whether subsequent exposure to local anaesthetics is safe. Two hundred and eight patients with a history of allergy to local anaesthesia were referred over a twenty-year period to our Anaesthetic Allergy Clinic. In this open study, intradermal testing was performed in three patients and progressive challenge in 202 patients. Four patients had immediate allergy and four patients delayed allergic reactions. One hundred and ninety-seven patients were not allergic to local anaesthetics. In 39 patients an adverse response to additives in local anaesthetic solutions could not be excluded. In all but one patient local anaesthesia has been given uneventfully subsequently. A history of allergy to local anaesthesia is unlikely to be genuine and local anaesthetic allergy is rare. In most instances LA allergy can be excluded from the history and the safety of LA verified by progressive challenge.

journal_name

Anaesth Intensive Care

authors

Fisher MM,Bowey CJ

doi

10.1177/0310057X9702500602

subject

Has Abstract

pub_date

1997-12-01 00:00:00

pages

611-4

issue

6

eissn

0310-057X

issn

1448-0271

pii

1997216

journal_volume

25

pub_type

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