Abstract:
:Since nine patients with infantile liver cirrhosis or hepatopathy associated with the Pi ZZ phenotype had been observed in recent years in the Children's Hospital of the University of Innsbruck, Tyrol, the distribution of the Pi types and the PiM subtypes was determined in the Tyrolean population. Apparently healthy blood donors (868) from different regions of Tyrol were examined. Isoelectricfocusing was used for classification of Pi types. The frequency of the allele PiZ was 0.0138, which corresponded to the range observed in other Middle European populations. The frequencies for the suballeles of PiM were PiM1 = 0.7062, PiM2 = 0.1480, and PiM3 = 0.1037. PiS had a frequency of 0.0225, the other rare alleles occurred with a combined frequency of 0.0058.
journal_name
Hum Genetjournal_title
Human geneticsauthors
Böhme A,Cleve H,Schönitzer D,Reissigl H,Kazda S,Müller Wdoi
10.1007/BF00291545subject
Has Abstractpub_date
1983-01-01 00:00:00pages
193-4issue
2eissn
0340-6717issn
1432-1203journal_volume
63pub_type
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