Abstract:
:T-lymphocyte subpopulations (Tg or "suppressor cells" and Tm or "helper cells") in the peripheral blood of 16 patients with malignant intracranial gliomas were analyzed. The number of Tm-lymphocytes was very close to normal in both pre- and postoperative samples, whereas Tg-lymphocytes were significantly increased preoperatively (18.55 +/- 1.11 vs. 12.72 +/- 1.19 p less than 0.001) and were still slightly higher than normal after operation and radiation treatment. These preliminary findings suggest a possible role of T-suppressor lymphocytes in the impairment of cell-mediated immunocompetence that has been observed repeatedly in patients with malignant gliomas.
journal_name
Neurosurgeryjournal_title
Neurosurgeryauthors
Gerosa MA,Olivi A,Rosenblum ML,Semenzato GP,Pezzutto Adoi
10.1227/00006123-198205000-00004subject
Has Abstractpub_date
1982-05-01 00:00:00pages
571-3issue
5eissn
0148-396Xissn
1524-4040journal_volume
10pub_type
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