Molecular weight forms of immunoreactive calcitonin in a patient with medullary carcinoma of the thyroid: dynamic studies with calcium, pentagastrin and somatostatin.

abstract：CONTEXT:Transient thelarche (TT), that is, the appearance, regression and subsequent reappearance of breast buds, is a frequent phenomenon, but little is known about pubertal transition in these girls. OBJECTIVE:To describe pubertal progression, growth, genotypes, reproductive hormones and growth factors in girls with...

journal_title：Clinical endocrinology

authors： Soto J,Pereira A,Busch AS,Almstrup K,Corvalan C,Iñiguez G,Juul A,Mericq V

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVE:We determined the ovarian response to human chorionic gonadotrophin (hCG) in terms of relaxin and progesterone secretion during the peri-implantation period of normal and failing pregnancies. We wished to test the hypotheses that relaxin production in failing pregnancies is different from that in normal pregn...

journal_title：Clinical endocrinology

authors： Stewart DR,Overstreet JW,Celniker AC,Hess DL,Cragun JR,Boyers SP,Lasley BL

更新日期：1993-04-01 00:00:00

abstract：OBJECTIVE:To study the reproducibility of 24-h serum growth hormone (GH) concentration profiles in adults. DESIGN:24-h serum GH concentrations were constructed by drawing blood samples at 20-min intervals. Four study occasions over a period of 1 year were chosen to assess the reproducibility. SUBJECTS:Six healthy adu...

journal_title：Clinical endocrinology

authors： Saini S,Hindmarsh PC,Matthews DR,Pringle PJ,Jones J,Preece MA,Brook CG

更新日期：1991-06-01 00:00:00

abstract：PURPOSE:To evaluate whether thyroid scintigraphy would alter the clinical management of patients referred for fine-needle aspiration cytology (FNA). METHODS:We reviewed the medical and imaging records of patients referred to our Department between 2016 and 2019. All the patients had to take a serum thyrotropin test ad...

journal_title：Clinical endocrinology

authors： Pirola I,Di Lodovico E,Casella C,Pezzaioli L,Facondo P,Ferlin A,Lombardi D,Cappelli C

更新日期：2020-12-17 00:00:00

abstract：:Six normal adult males were given clonidine and GHRH either separately, or in combination, in random order. The peak serum GH concentrations elicited by clonidine or GHRH were variable but one factor influencing the GH response to GHRH was the GH secretory status in the hour prior to the administration of the GHRH. Pe...

journal_title：Clinical endocrinology

authors： Suri D,Hindmarsh PC,Brain CE,Pringle PJ,Brook CG

更新日期：1990-09-01 00:00:00

abstract：:We describe a patient with multiple endocrine adenomatosis Type I, characterized by pituitary-dependent Cushing's Syndrome, marked hyperprolactinaemia, primary hyperparathyroidism and hyperinsulinism leading to hypoglycaemia. The patient subsequently developed an exocrine pancreatic carcinoma at the age of 32 years fr...

journal_title：Clinical endocrinology

authors： Oliver MH,Drury PL,Van't Hoff W

更新日期：1983-05-01 00:00:00

abstract：:delta 5 and delta 4 steroid levels were studied in the plasma and cyst fluid of women with gross cystic breast disease (GCBD). In luteal phase a significant increase in plasma levels (mean +/- SEM) of DHA (11.2 +/- 2.4 ng/ml), DHAS (1.45 +/- 0.6 micrograms/ml) and cortisol 277 +/- 15.7 ng/ml) was found; in follicular ...

journal_title：Clinical endocrinology

authors： Inaudi P,Bernabei A,Gioffré W,Franchi F,Mazzullo G,De Leo V,D'Antona N

更新日期：1987-12-01 00:00:00

abstract：OBJECTIVE:The aim was to study the relationship between growth hormone (GH) and insulin-like growth factor-I (IGF-I) in critically ill patients. DESIGN:Case-control study of critically ill patients admitted to the intensive care unit was carried out. PATIENTS:Six critically ill patients (51-78 years) who required ven...

journal_title：Clinical endocrinology

authors： Ross R,Miell J,Freeman E,Jones J,Matthews D,Preece M,Buchanan C

更新日期：1991-07-01 00:00:00

abstract：OBJECTIVES:The Asp727Glu polymorphism in the TSH receptor (TSHR) gene is associated with serum TSH levels. However, the proportion of genetic variation accounted for by this polymorphism is unknown. In this study, we (1) examined the association of the Asp727Glu polymorphism with thyroid size, serum levels of TSH, thyr...

journal_title：Clinical endocrinology

authors： Hansen PS,van der Deure WM,Peeters RP,Iachine I,Fenger M,Sørensen TI,Kyvik KO,Visser TJ,Hegedüs L

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Women with previous gestational diabetes (pGDM) are at risk of developing Type 2 diabetes. Glucagon-like peptide-1 (GLP-1) potentiates the insulin response to oral glucose, and its secretion is diminished in Type 2 diabetes. The aim of the study was to see if decreased GLP-1 secretion might be ...

journal_title：Clinical endocrinology

authors： Forbes S,Moonan M,Robinson S,Anyaoku V,Patterson M,Murphy KG,Ghatei MA,Bloom SR,Johnston DG

更新日期：2005-01-01 00:00:00

abstract：:Familial Isolated Pituitary Adenomas (FIPA), an autosomal dominant disease with low penetrance is being increasingly recognized. FIPA families can be divided into two distinct groups based on genetic and phenotypic features. Patients with mutations in the aryl hydrocarbon receptor-interacting protein (AIP) gene are ch...

journal_title：Clinical endocrinology

authors： Korbonits M,Storr H,Kumar AV

更新日期：2012-09-01 00:00:00

abstract：:1,24,25-trihydroxyvitamin D3 has been detected in human serum using a sensitive radioimmunoassay. Tritiated 1,24,25-trihydroxyvitamin D3 was synthesized biologically and used as tracer to monitor the recovery of endogenous metabolite during isolation from serum. Circulating 1,24,25(OH)3D3 in normal subjects ranged fro...

journal_title：Clinical endocrinology

authors： Clemens TL,Fraher LJ,Sandler LM,O'Riordan JL

更新日期：1982-04-01 00:00:00

abstract：OBJECTIVE:Serum thyroglobulin (Tg) has been associated with a number of thyroid disorders and has been proposed as an indicator of iodine deficiency in a population. However, few studies have addressed the epidemiology of Tg in a population-based setting or in the context of exposure to radioactive iodine-131 (I-131). ...

journal_title：Clinical endocrinology

authors： Cahoon EK,Rozhko A,Hatch M,Polyanskaya O,Ostroumova E,Tang M,Nadirov E,Yauseyenka V,Savasteeva I,McConnell RJ,Pfeiffer RM,Brenner AV

更新日期：2013-07-01 00:00:00

abstract：:Ten patients (seven women, three men) with active acromegaly, five previously treated and five newly diagnosed, were included in an open-label prospective trial of 3 daily subcutaneous injections of the long-acting somatostatin analogue SMS 201-995 (Sandostatin) at increasing doses in order to obtain maximum growth ho...

journal_title：Clinical endocrinology

authors： Shi YF,Harris AG,Zhu XF,Deng JY

更新日期：1990-06-01 00:00:00

abstract：:The cardiovascular response and the changes of plasma arginine vasopressin (AVP) concentration following graded doses of AVP infused intravenously have been defined in six normal young men. The same measurements were also made during fluid deprivation in a patient with both nephrogenic diabetes insipidus and systemic ...

journal_title：Clinical endocrinology

authors： Khokhar AM,Slater JD,Ma J,Ramage CM

更新日期：1980-09-01 00:00:00

abstract：:Sera from patients with Graves' disease and Hashimoto's thyroiditis were reacted with normal T lymphocyte preparations in an attempt to detect binding of immunoglobulin G (IgG) to T cells. Sera from normal subjects and patients with toxic adenomas served as controls. Each serum was reacted with at least three differen...

journal_title：Clinical endocrinology

authors： Pacini F,Sridama V,Pressendo J,DeGroot LJ,Medof ME

更新日期：1983-07-01 00:00:00

abstract：:Twenty-seven patients starting regular haemodialysis were treated with a 1 microgram daily dose of 1alpha-hydroxyvitamin D3 and concurrent aluminium hydroxide therapy to prevent hyperphosphataemia. There was an increase in plasma calcium, but no significant improvement in plasma alkaline phosphatase activity or parath...

journal_title：Clinical endocrinology

authors： Walker GS,Peacock M,Aaron J,Robinson PJ,Davison AM

更新日期：1977-12-01 00:00:00

abstract：OBJECTIVE:To assess the relationship between circulating leptin levels, bone mineral content and density in the elderly. DESIGN:A cross-sectional study. PATIENTS:A cohort of 92 men and 171 women, with ages ranging from 68 to 75 years, selected as a healthy and normal functioning group, in the city centre of Verona. ...

journal_title：Clinical endocrinology

authors： Zoico E,Zamboni M,Adami S,Vettor R,Mazzali G,Tosoni P,Bissoli L,Bosello O

更新日期：2003-07-01 00:00:00

abstract：:The possibility that oleic acid is the thyroxine binding inhibitor in the serum of seriously ill patients was investigated. 3H-Oleic acid was shown to bind directly to human thyroxine-binding globulin (TBG) by the techniques of one and two-dimensional immunoelectrophoresis in combination with autoradiography. However,...

journal_title：Clinical endocrinology

authors： Haynes IG,Lockett SJ,Farmer MJ,Fitch NJ,Bradwell AR,Sheppard MC,Ramsden DB

更新日期：1989-07-01 00:00:00

abstract：OBJECTIVE:It is generally accepted that there is no clinically significant circadian variation in total insulin-like growth factor (IGF)-I or total IGF-II in healthy subjects. In contrast there is a significant nocturnal decrease in free IGF-I in healthy subjects, corresponding to the nocturnal increase in IGF binding ...

journal_title：Clinical endocrinology

authors： Skjaerbaek C,Frystyk J,Kaal A,Laursen T,Møller J,Weeke J,Jørgensen JO,Sandahl Christiansen J,Orskov H

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:A GH deficiency-like phenotype with normal or high hGH secretion, pathologically low IGF-I serum levels, and catch-up growth under treatment with recombinant hGH is suggestive of the presence of biologically inactive hGH syndrome, whose presumably heterogenous molecular basis is substantially unknown. DESIG...

journal_title：Clinical endocrinology

authors： Binder G,Benz MR,Elmlinger M,Pflaum CD,Strasburger CJ,Ranke MB

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND:Adrenal disorders such as congenital adrenal hyperplasia result in abnormal adrenal size and morphology, but little is known about the clinical value of magnetic resonance imaging (MRI) in determining adrenal volume. OBJECTIVE:To evaluate the potential usefulness of MR methodology, to estimate adrenal size ...

journal_title：Clinical endocrinology

authors： Mouritsen A,Johansen ML,Wohlfahrt-Veje C,Hagen CP,Tinggaard J,Mieritz MG,Tefre de Renzy-Martin K,Soeborg T,Fallentin E,Juul A,Main KM

更新日期：2014-08-01 00:00:00

abstract：:The human population which lives and works in polar environments has been increasing steadily over the last 15 years. Very little is known about how these residents adjust to their environment. Cold adaptation in man is a poorly understood phenomenon. Euthermic mammals maintain body temperature during cold exposure vi...

journal_title：Clinical endocrinology

authors： Reed HL,Burman KD,Shakir KM,O'Brian JT

更新日期：1986-07-01 00:00:00

abstract：OBJECTIVE:Recent studies have suggested that patients receiving thyroxine are at increased risk of osteoporosis. We set out to measure bone mineral densities in two groups of post-menopausal women receiving thyroxine replacement therapy (those with serum TSH levels persistently suppressed or non-suppressed) and to comp...

journal_title：Clinical endocrinology

authors： Grant DJ,McMurdo ME,Mole PA,Paterson CR,Davies RR

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND:In patients with acromegaly serum IGF-I is increasingly used as a marker of disease activity. As a result, the relationship between serum GH and IGF-I is of profound interest. Healthy females secrete three times more GH than males but have broadly similar serum IGF-I levels, and women with GH deficiency requ...

journal_title：Clinical endocrinology

authors： Parkinson C,Renehan AG,Ryder WD,O'Dwyer ST,Shalet SM,Trainer PJ

更新日期：2002-07-01 00:00:00

abstract：:The best long-term results of transsphenoidal surgery appear to be in those patients who have unmeasurable serum cortisol levels in the immediate post-operative period. This appears to be due to isolated ACTH deficiency in the remaining normal pituitary gland. In our experience, however, long-term clinical remission m...

journal_title：Clinical endocrinology

authors： McCance DR,Besser M,Atkinson AB

更新日期：1996-01-01 00:00:00

abstract：OBJECTIVE:Small, dense low-density lipoproteins (LDL) are a feature of the metabolic syndrome (MS) but their predictive role still remains to be established. We performed a 2-year follow-up study in 124 subjects with MS (63 +/- 6 years), as defined by the American Heart Association/National Heart, Lung and Blood Instit...

journal_title：Clinical endocrinology

authors： Rizzo M,Pernice V,Frasheri A,Di Lorenzo G,Rini GB,Spinas GA,Berneis K

更新日期：2009-06-01 00:00:00

abstract：OBJECTIVES:To report and explore potential reasons for undetectable or low-normal serum intact PTH levels in patients with surgically verified primary hyperparathyroidism with parathyroid adenomas, review the relevant literature, and offer suggestions for management of such patients occasionally encountered in clinical...

journal_title：Clinical endocrinology

authors： Bhadada SK,Cardenas M,Bhansali A,Mittal BR,Behera A,Chanukya GV,Nahar U,Rao DS

更新日期：2008-09-01 00:00:00

abstract：:The results obtained with a new test of prolactin (PRL) release in six panhypopituitary patients as compared to fourteen normal subjects (eight females and six males) are presented. The test consists of the i.m. administration of 100 mg of sulpiride and the measurement of plasma PRL by a double antibody radioimmunoass...

journal_title：Clinical endocrinology

authors： Batrinos ML,Pavlou SN,Pitoulis SA,Sfikaki AP,Alexandrides TK,Piaditis GP

更新日期：1978-03-01 00:00:00

abstract：OBJECTIVE:To assess the effect of nutritional supplementation on growth and puberty in constitutionally delayed children. PATIENTS:One hundred and two boys, 13.6-15.5 years of age, who were referred because of short stature and delayed puberty. METHODS:The boys were randomly allocated to one of the following treatmen...

journal_title：Clinical endocrinology

authors： Zadik Z,Sinai T,Zung A,Reifen R

更新日期：2004-06-01 00:00:00