Abstract:
:Esterase D levels from 200 retinoblastoma patients have been measured in an attempt to identify individuals carrying deletions of chromosome region 13q14. In this series 75% had bilateral tumours and 23% were familial. Of nine patients identified as having low esterase D levels, five had not previously been diagnosed as deletion carriers. These observations demonstrate the benefit of screening retinoblastoma populations for esterase D deficiency.
journal_name
Hum Genetjournal_title
Human geneticsauthors
Cowell JK,Rutland P,Jay M,Hungerford Jdoi
10.1007/BF00283938subject
Has Abstractpub_date
1986-02-01 00:00:00pages
164-7issue
2eissn
0340-6717issn
1432-1203journal_volume
72pub_type
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