Hematoporphyrin derivative photocytotoxicity of human glioblastoma in cell culture.

abstract：OBJECTIVE:Adult gliomas have indistinct borders. As the ratio of neoplastic cells to normal cells becomes lower, the ability to detect these cells diminishes. We describe a device designed to augment intraoperative identification of both solid tumor and infiltrating tumor margins. METHODS:A novel, intraoperative, opti...

journal_title：Neurosurgery

authors： Toms SA,Lin WC,Weil RJ,Johnson MD,Jansen ED,Mahadevan-Jansen A

更新日期：2005-10-01 00:00:00

abstract：:Intracranial pressure sensors and subdural and subgaleal sensing tambours were used to measure the pressure difference between the intracranial and subgaleal spaces in two monkeys. The pressure differential was transmitted to fluid bathing a piston, to which an isotope source (145Pm) was attached. The radiation signal...

journal_title：Neurosurgery

authors： Meyer GA,Millis RM,Budzinski J

更新日期：1978-01-01 00:00:00

abstract：BACKGROUND:Advanced cervical spondylosis (CS) can cause structural damage to the spinal cord resulting in long-term neurological impairment including neck pain and motor weakness. We hypothesized long-term structural reorganization within the brain in patients with CS. OBJECTIVE:To explore the associations between cor...

journal_title：Neurosurgery

authors： Woodworth DC,Holly LT,Mayer EA,Salamon N,Ellingson BM

更新日期：2019-03-01 00:00:00

abstract：PURPOSE:To compare a newly released vascular clip system (Vascular Clip-applier System; Auto Suture Company, Norwalk, CT) designed for sutureless vessel closures and anastomoses with standard suture closure of carotid arteriotomies after carotid endarterectomies. PATIENTS AND METHODS:Sixteen consecutive patients with ...

journal_title：Neurosurgery

authors： Findlay JM,Megyesi JF

更新日期：1998-03-01 00:00:00

abstract：OBJECTIVE:We sought to determine the risk of adverse outcome after contemporary surgical treatment of patients with unruptured intracranial aneurysms in the United States. Patient, surgeon, and hospital characteristics were tested as potential outcome predictors, with particular attention to the surgeon's and hospital'...

journal_title：Neurosurgery

authors： Barker FG 2nd,Amin-Hanjani S,Butler WE,Ogilvy CS,Carter BS

更新日期：2003-05-01 00:00:00

abstract：OBJECTIVE:To further elucidate the importance of anatomic variations in morphology of the foramen magnum and associated clinical implications, we conducted a morphometric study. METHODS:Seventy-two dry skulls were used for this study. Digital images were obtained of the foramen magnum from an inferior view. These imag...

journal_title：Neurosurgery

authors： Tubbs RS,Griessenauer CJ,Loukas M,Shoja MM,Cohen-Gadol AA

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVE:Anterior microforaminotomy for spondylotic cervical myelopathy is reported with surgical results. METHODS:A retrospective study was performed for 40 patients with spondylotic cervical myelopathy who had been surgically treated with anterior microforaminotomy at the University of Pittsburgh between April 1994...

journal_title：Neurosurgery

authors： Jho HD,Kim MH,Kim WK

更新日期：2002-11-01 00:00:00

abstract：OBJECTIVE AND IMPORTANCE:We describe a patient with a tentorial dural arteriovenous fistula who presented with ipsilateral hemifacial spasm. CLINICAL PRESENTATION:A 50-year-old man sought treatment for left facial twitching that worsened over 6 months. Magnetic resonance imaging and catheter angiography demonstrated a...

journal_title：Neurosurgery

authors： Deshmukh VR,Maughan PH,Spetzler RF

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:With the decrease in the number of cerebral aneurysms treated surgically and the increase of complexity of those treated surgically, there is a need for simulation-based tools to teach future neurosurgeons the operative techniques of aneurysm clipping. OBJECTIVE:To develop and evaluate the usefulness of a n...

journal_title：Neurosurgery

authors： Alaraj A,Luciano CJ,Bailey DP,Elsenousi A,Roitberg BZ,Bernardo A,Banerjee PP,Charbel FT

更新日期：2015-03-01 00:00:00

abstract：:Unexplained intraoperative or postoperative hemorrhage occurs in certain cases in the surgery of large arteriovenous malformations (AVMs), which are defined as those with maximal diameter of the nidus larger than 5 cm. Immediate postoperative angiograms were evaluated with reference to whether such hemorrhage could be...

journal_title：Neurosurgery

authors： Takemae T,Kobayashi S,Sugita K

更新日期：1993-09-01 00:00:00

abstract：OBJECTIVE:Ion transporters play pivotal roles in cancer cell migration in general and in glioblastomas (GBMs) in particular. However, the specific role of Na/K-ATPase (the sodium pump) and, in particular, its alpha1 subunit, has remained unexplored in GBMs. MATERIALS AND METHODS:The expression of Na+/K+ -ATPase alpha1...

journal_title：Neurosurgery

authors： Lefranc F,Mijatovic T,Kondo Y,Sauvage S,Roland I,Debeir O,Krstic D,Vasic V,Gailly P,Kondo S,Blanco G,Kiss R

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVE AND IMPORTANCE:A unique case of spontaneous pneumocephalus is described. It appeared a few years after the uneventful introduction of a cerebrospinal fluid shunt and was probably attributable to a defect of the posterior mastoid plate. CLINICAL PRESENTATION:A 65-year-old man presented with a subacute onset o...

journal_title：Neurosurgery

authors： Kanner AA,Nageris BI,Chaimoff M,Rappaport ZH

更新日期：2000-04-01 00:00:00

abstract：OBJECTIVE:Interhemisperic lipomas are almost always associated with hypogenesis or agenesis of the corpus callosum. These lesions are stable. CLINICAL PRESENTATION:We report a case of an interhemispheric lipoma in a 72-year-old man who had undergone myelolipomatous differentiation. INTERVENTION:Gross total excision o...

journal_title：Neurosurgery

authors： Suri V,Sharma MC,Suri A,Karak AK,Garg A,Sarkar C,Jain D

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:Spinal cord dose limits are critically important for the safe practice of spine stereotactic body radiotherapy (SBRT). However, the effect of inherent spinal cord motion on cord dose in SBRT is unknown. OBJECTIVE:To assess the effects of cord motion on spinal cord dose in SBRT. METHODS:Dynamic balanced fas...

journal_title：Neurosurgery

authors： Oztek MA,Mayr NA,Mossa-Basha M,Nyflot M,Sponseller PA,Wu W,Hofstetter CP,Saigal R,Bowen SR,Hippe DS,Yuh WTC,Stewart RD,Lo SS

更新日期：2020-06-04 00:00:00

abstract：BACKGROUND:Tumor-associated sacral insufficiency fractures (SIF) present a significant clinical challenge. As survival increases for many malignancies, sacral fractures associated with metastases, sacral or extended pelvic radiation, and paraneoplastic osteoporosis are increasingly common and yet remain difficult to tr...

journal_title：Neurosurgery

authors： Moussazadeh N,Laufer I,Werner T,Krol G,Boland P,Bilsky MH,Lis E

更新日期：2015-04-01 00:00:00

abstract：:A retrospective analysis of 50 consecutive patients treated with chemonucleolysis and 50 treated with microlumbar discectomy was carried out. Similar clinical criteria for the diagnosis of "virgin" herniated lumbar discs were used. All patients had low back or radicular pain unrelieved by a minimum of 4 weeks of conse...

journal_title：Neurosurgery

authors： Maroon JC,Abla A

更新日期：1985-05-01 00:00:00

abstract：OBJECTIVE:To improve intraoperative observation of unexposed anatomic features and to verify surgical correction, a mobile computed tomographic (CT) scanner has been introduced into the operating room. To date, intraoperative CT scanning has been used predominantly for intracranial procedures. We report on the expanded...

journal_title：Neurosurgery

authors： Hum B,Feigenbaum F,Cleary K,Henderson FC

更新日期：2000-08-01 00:00:00

abstract：OBJECTIVE:To describe the pathological features of three very similar and unusual primary central nervous system tumors that are not readily recognized as conventional ependymomas but which, by ultrastructural examination, have an ependymomatous character. METHODS:Three distinctive tumors were found in a review of our...

journal_title：Neurosurgery

authors： Kleinman GM,Zagzag D,Miller DC

更新日期：2003-09-01 00:00:00

abstract：OBJECTIVE:To describe a modification of the pterional approach (PT), the minipterional craniotomy (MPT), and compare the anatomic exposure provided by these two approaches. METHODS:The anatomic exposure offered by the MPT and PT were compared in eight sides of cadaver heads using a computerized tracking system, a robo...

journal_title：Neurosurgery

authors： Figueiredo EG,Deshmukh P,Nakaji P,Crusius MU,Crawford N,Spetzler RF,Preul MC

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVE AND IMPORTANCE:To describe the use of a new imaging tool, angiographic computed tomography, for visualization of cell opening and strut prolapse of a Neuroform 2 stent (Boston Scientific/Target, Fremont, CA) placed in curved vasculature for treatment of a basilar tip aneurysm. CLINICAL PRESENTATION:A 46-year...

journal_title：Neurosurgery

authors： Benndorf G,Claus B,Strother CM,Chang L,Klucznik RP

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:Cerebral cavernous malformations (CCM) may lead to repetitive intracerebral hemorrhage. In selected cases, a surgical resection is indicated. OBJECTIVE:To identify magnetic resonance imaging (MRI) features of CCM that correlate with the difficulty of dissection and postoperative outcome. METHODS:This study...

journal_title：Neurosurgery

authors： Dammann P,Wrede K,Jabbarli R,Müller O,Mönninghoff C,Forsting M,Sure U

更新日期：2017-09-01 00:00:00

abstract：:Instability of the atlantoaxial complex may result from inflammatory, traumatic, congenital, neoplastic, or degenerative disorders and often requires surgical stabilization. Initial dorsal wiring techniques allow safe fixation but require rigid external immobilization and have been associated with high fusion failure ...

journal_title：Neurosurgery

authors： Menendez JA,Wright NM

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVE:To evaluate, regardless of the clinical results, the contribution of combining functional magnetic resonance imaging (fMRI) with intraoperative cortical brain mapping (iCM) as functional targeting methods for epidural chronic motor cortex stimulation (MCS) in refractory neuropathic pain. METHODS:Eighteen neu...

journal_title：Neurosurgery

authors： Pirotte B,Voordecker P,Neugroschl C,Baleriaux D,Wikler D,Metens T,Denolin V,Joffroy A,Massager N,Brotchi J,Levivier M

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVE:Herpes virus encephalitis is a rare, life-threatening complication of therapy in patients with brain tumors. A surgical therapeutic approach may be needed because the infection can be resistant to acyclovir in immunocompromised patients, and complications and long-term sequelae are frequent. CLINICAL PRESENT...

journal_title：Neurosurgery

authors： Sánchez-Carpintero R,Aguilera S,Idoate M,Bejarano B

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:Although most adult brachial plexus injuries result from high-speed mechanisms, no laboratory model has been created to mimic rapid-stretch nerve injuries. Understanding the biomechanical response of nerves to rapid stretch is essential to understanding clinical injury patterns and developing models that mim...

journal_title：Neurosurgery

authors： Mahan MA,Yeoh S,Monson K,Light A

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Acromegaly is a disorder characterized by hypersecretion of growth hormone caused by a growth hormone-secreting pituitary adenoma. OBJECTIVE:To evaluate the long-term efficacy and safety of repeat transsphenoidal surgery for persistent or recurrent acromegaly. METHODS:We retrospectively reviewed records fo...

journal_title：Neurosurgery

authors： Yamada S,Fukuhara N,Oyama K,Takeshita A,Takeuchi Y

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVE AND IMPORTANCE:Vestibular schwannomas with meningioma islets have been rarely reported in the literature; they have been observed only among patients with neurofibromatosis Type II. We present a case of a sporadic mixed tumor in a patient without neurofibromatosis Type II that was not suspected before surgery...

journal_title：Neurosurgery

authors： Lüdemann W,Stan AC,Tatagiba M,Samii M

更新日期：2000-08-01 00:00:00

abstract：BACKGROUND:Somatosensory evoked potential (SSEP) monitoring is used during intracranial aneurysm surgery to track the effects of anesthesia, surgical manipulation, and temporary clipping. OBJECTIVE:To present the outcomes of 663 consecutive patients (691 cases) treated surgically for intracranial aneurysms who underwe...

journal_title：Neurosurgery

authors： Wicks RT,Pradilla G,Raza SM,Hadelsberg U,Coon AL,Huang J,Tamargo RJ

更新日期：2012-05-01 00:00:00

abstract：:Neurosurgery is experiencing a period of acute change driven by 2 forces: (1) the perception that the healthcare system in the United States is wasteful and that patients are receiving low "value" care, (2) the belief that quality and long-term outcomes can be measured accurately. We believe 3 important shifts will em...

journal_title：Neurosurgery

authors： Kim DH,Dagi TF,Bean JR

更新日期：2017-04-01 00:00:00

abstract：:We have divided head injury into three categories based on the Glasgow Coma Scale (GCS) (severe, 3-8; moderate, 9-12; and minor, 13-15). In a previous report, we described significant disability after minor head injury. The present report describes 199 patients with moderate head injury, 159 of whom underwent follow-u...

journal_title：Neurosurgery

authors： Rimel RW,Giordani B,Barth JT,Jane JA

更新日期：1982-09-01 00:00:00