Abstract:
:Estrogens have previously been reported to be proconvulsants in adult animals. This study evaluated the effects of acute, high-dose estrogen administration on rate of kindling in immature rats. No significant differences in rate of kindling between the estrogen-treated rats and controls were noted. This study, using the kindling model, demonstrates that estradiol does not have a significant effect on the development of seizures in the immature animal.
journal_name
Epilepsiajournal_title
Epilepsiaauthors
Schultz-Krohn WA,Thompson J,Holmes GLdoi
10.1111/j.1528-1157.1986.tb03580.xsubject
Has Abstractpub_date
1986-09-01 00:00:00pages
538-41issue
5eissn
0013-9580issn
1528-1167journal_volume
27pub_type
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