A rapid and simplified extraction of haloperidol from plasma or serum with bond elut C18 cartridge for analysis by high performance liquid chromatography.

Abstract:

:This method for the determination of haloperidol (HAL) in plasma is based on high-performance liquid chromatography (HPLC) with a reversed-phase column, ODS-C18. HAL is rapidly extracted from human plasma by using Bond Elut C18 cartridge and its recovery is over 90%. The mobile phase is a mixture of 1% acetate/acetonitrile/tetrahydrofuran/triethylamine (69.5: 28.2:1.9:0.4, by vol.). The method is rapid, simple and free from intereferences and gives good precision.

journal_name

Forensic Sci Int

authors

Hayakari M,Hashimoto Y,Kita T,Murakami S

doi

10.1016/0379-0738(87)90025-9

subject

Has Abstract

pub_date

1987-09-01 00:00:00

pages

73-81

issue

1

eissn

0379-0738

issn

1872-6283

pii

0379-0738(87)90025-9

journal_volume

35

pub_type

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