Radiation therapy in the treatment of cerebral astrocytoma.

abstract：BACKGROUND:Biochemical alterations associated with mechanical stress have been explored as an initiating step in the pathological progression of ligamentum flavum hypertrophy (LFH); however, this mechanism remains poorly understood. Recently, the inflammation induced after mechanical stress and the subsequent response ...

journal_title：Neurosurgery

authors： Hur JW,Kim BJ,Park JH,Kim JH,Park YK,Kwon TH,Moon HJ

更新日期：2015-08-01 00:00:00

abstract：OBJECTIVE AND IMPORTANCE:Traditionally, thoracic fractures that require anterior stabilization are treated through an open thoracotomy approach. Thoracoscopic instrumentation avoids many of the complications associated with an open thoracotomy but is technically challenging. We report the first cases of dual-rod intern...

journal_title：Neurosurgery

authors： Horn EM,Henn JS,Lemole GM Jr,Hott JS,Dickman CA

更新日期：2004-05-01 00:00:00

abstract：:Traditionally, the ideal academic neurosurgeon has been a "quadruple threat," with excellence in clinical work, teaching, research, and administration. This tradition was best exemplified in Harvey Cushing, who developed the field of neurosurgery 90 years ago. This paradigm will probably have to change as academic neu...

journal_title：Neurosurgery

authors： Black PM

更新日期：2006-03-01 00:00:00

abstract：:It is well known that the Horsley-Clarke frame was developed and first used by Robert Henry Clarke and the pioneer neurosurgeon Victor Horsley in 1906 for making lesions in the central nervous system of animals. The Horsley-Clarke frame was extensively used throughout the next 4 decades for excitation and lesion produ...

journal_title：Neurosurgery

authors： Jensen RL,Stone JL,Hayne RA

更新日期：1996-03-01 00:00:00

abstract：OBJECTIVE:To report our experience in treatment of arteriovenous malformations (AVMs) using a new liquid embolic agent, Onyx (Micro Therapeutics, Inc., Irvine, CA). METHODS:Between January 1998 and May 1999, 23 patients (8 men and 15 women) were treated. The patients' average age was 40 years, with seizure being the m...

journal_title：Neurosurgery

authors： Jahan R,Murayama Y,Gobin YP,Duckwiler GR,Vinters HV,Viñuela F

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND AND IMPORTANCE:Comminuted sacral fractures present significant challenges for operative management. Open and percutaneous sacroiliac screws have been used for stabilization but carry not insignificant rates of complications, including wound infection for the former and malposition and neurological injury for...

journal_title：Neurosurgery

authors： Hong J,Spire WJ,Simmons NE

更新日期：2013-03-01 00:00:00

abstract：:Reliable Assessment of the probability that a head injury patient harbors a surgical intracranial lesion is critical to both triage and treatment. The authors analyzed data from 608 patients with severe head injuries (Glasgow Coma Scale score, < or = 8) in the Traumatic Coma Data Bank to assess the reliability of pupi...

journal_title：Neurosurgery

authors： Chesnut RM,Gautille T,Blunt BA,Klauber MR,Marshall LE

更新日期：1994-05-01 00:00:00

abstract：:This report details the surgical treatment of 44 patients with aneurysms of the vertebral and basilar arteries. Three different surgical approaches were utilized depending on the location of the aneurysm. These were an anterior supratentorial approach, a lateral suboccipital approach, and a combined supratentorial and...

journal_title：Neurosurgery

authors： Solomon RA,Stein BM

更新日期：1988-08-01 00:00:00

abstract：BACKGROUND:Minimally invasive surgery procedures, including stereotactic catheter aspiration and clearance of intracerebral hemorrhage (ICH) with recombinant tissue plasminogen activator hold a promise to improve outcome of supratentorial brain hemorrhage, a morbid and disabling type of stroke. A recently completed Pha...

journal_title：Neurosurgery

authors： Awad IA,Polster SP,Carrión-Penagos J,Thompson RE,Cao Y,Stadnik A,Money PL,Fam MD,Koskimäki J,Girard R,Lane K,McBee N,Ziai W,Hao Y,Dodd R,Carlson AP,Camarata PJ,Caron JL,Harrigan MR,Gregson BA,Mendelow AD,Zuccare

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Spine and nonspine skeletal metastases occur in more than 80% of patients with prostate cancer. OBJECTIVE:To examine the characteristics of the patient population undergoing surgery for the treatment of prostate cancer metastatic to the spine. METHODS:A retrospective chart review was performed on all patie...

journal_title：Neurosurgery

authors： Chohan MO,Kahn S,Cederquist G,Reiner AS,Schwab J,Laufer I,Bilsky M

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVE AND IMPORTANCE:Ethmoidal dural arteriovenous fistulas (AVFs) are rare intracranial lesions associated with a high risk of intracranial hemorrhage. Reported hemorrhage rates have ranged from 62 to 91%, and an aggressive clinical course is more likely than a benign clinical course. We describe the first case of...

journal_title：Neurosurgery

authors： Deshmukh VR,Chang S,Albuquerque FC,McDougall CG,Spetzler RF

更新日期：2005-10-01 00:00:00

abstract：:The effects of mannitol on the cerebral microcirculation were studied using isolated perfused intracerebral (parenchymal) arterioles in rats. After vessels developed spontaneous tone, increasing concentrations of mannitol were applied extraluminally. Mannitol induced vasodilation in a dose-dependent manner. In an init...

journal_title：Neurosurgery

authors： Takayasu N,Dacey RG Jr

更新日期：1989-11-01 00:00:00

abstract：OBJECTIVE:A two-stage approach using orbitozygomatic (OZ) and retrosigmoid (RS) craniotomies is one option for the management of petroclival lesions with supratentorial extension. The goal of this study was to investigate the supratentorial and infratentorial exposures of the clivus obtained through this staged approac...

journal_title：Neurosurgery

authors： Little AS,Jittapiromsak P,Crawford NR,Deshmukh P,Preul MC,Spetzler RF,Bambakidis NC

更新日期：2008-05-01 00:00:00

abstract：:IN 1891, Dr. Cemil Topuzlu operated on a brain abscess that originated as a complication of a depression fracture of the cranial inner table. The patient presented with Jacksonian seizures on his left side after a sharp trauma resulting in a 15 cm-long scalp laceration and underlying linear cranial fracture in the rig...

journal_title：Neurosurgery

authors： Mut M,Dinç G,Naderi S

更新日期：2007-10-01 00:00:00

abstract：:The anatomic reorganization of the subnucleus that controls the stylohyoid muscle (the stylohyoid subnucleus) within the brain stem facial nucleus was studied after regeneration of the facial nerve in adult rats. Horseradish peroxidase was injected into the right stylohyoid muscle 3 to 21 months after transection and ...

journal_title：Neurosurgery

authors： Fernandez E,Pallini R,Marchese E,Lauretti L,La Marca F

更新日期：1995-09-01 00:00:00

abstract：:Traumatic atlanto-occipital (A-O) dislocation is a rare injury that is associated with a high mortality rate. We are presenting the case of a 5-year-old child with this entity to illustrate the mechanism of injury, the often-confusing clinical picture, and the use of diaphragmatic fluoroscopy to localize the neurologi...

journal_title：Neurosurgery

authors： Pang D,Wilberger JE Jr

更新日期：1980-11-01 00:00:00

abstract：OBJECTIVE:Intraoperative detection of residual tumor tissue in glioma surgery remains an important challenge because the extent of tumor removal is related to the prognosis of the disease. Multiphoton excited fluorescence tomography of living tissues provides high-resolution structural and photochemical imaging at a su...

journal_title：Neurosurgery

authors： Leppert J,Krajewski J,Kantelhardt SR,Schlaffer S,Petkus N,Reusche E,Hüttmann G,Giese A

更新日期：2006-04-01 00:00:00

abstract：:The recently described multiple tumor suppressor 1/cyclin-dependent kinase inhibitor 2 (MTS1/CDKN2) gene, encoding the cyclin-dependent kinase 4 inhibitor p16, is mutated in a wide variety of tumor cell lines, including gliomas. To investigate the possible role of this gene in the genesis of the central nervous system...

journal_title：Neurosurgery

authors： Raffel C,Ueki K,Harsh GR 4th,Louis DN

更新日期：1995-05-01 00:00:00

abstract：:The authors report two patients with a rare complication of parent artery narrowing that occurred 3 and 6 months after aneurysm surgery. In both cases, the stenosed arteries had been wrapped around their entire circumferences with neurosurgical sponge (cotton linter) and coated with plastic adhesive (cyanoacrylate com...

journal_title：Neurosurgery

authors： Kurita H,Shiokawa Y,Segawa H,Kirino T

更新日期：1995-06-01 00:00:00

abstract：BACKGROUND:Neuromodulation is used to restore neural function in disorders that stem from an imbalance in the activity of specific neural networks when they prove refractory to pharmacological therapy. The Kir2.1 gene contributes to stabilizing the resting potential below the threshold of activation of voltage-gated so...

journal_title：Neurosurgery

authors： Boulis NM,Handy CR,Krudy CA,Donnelly EM,Federici T,Franz CK,Barrow EM,Teng Q,Kumar P,Cress D

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVE:In this study, the incidence, etiologies, and management with respect to clinical outcome of patients with iatrogenic aneurysmal rupture during attempted coil embolization of intracranial aneurysms are reviewed. METHODS:A retrospective analysis was conducted of 274 patients with intracranial aneurysms treate...

journal_title：Neurosurgery

authors： Levy E,Koebbe CJ,Horowitz MB,Jungreis CA,Pride GL,Dutton K,Kassam A,Purdy PD

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND:Patients who survive aneurysmal subarachnoid hemorrhage (aSAH) are at risk for delayed neurological deficits (DND) and cerebral infarction. In this exploratory cohort comparison analysis, we compared in-hospital outcomes of aSAH patients administered a low-dose intravenous heparin (LDIVH) infusion (12 U/kg/h...

journal_title：Neurosurgery

authors： Kole MJ,Wessell AP,Ugiliweneza B,Cannarsa GJ,Fortuny E,Stokum JA,Shea P,Chryssikos T,Khattar NK,Crabill GA,Schreibman DL,Badjatia N,Gandhi D,Aldrich EF,James RF,Simard JM

更新日期：2020-12-02 00:00:00

abstract：BACKGROUND:Classification of middle cerebral artery (MCA) aneurysms is sometimes difficult because the identification of the main MCA bifurcation, the key for accurate classification of MCA aneurysms, is inconsistent and somewhat subjective. OBJECTIVE:To use the meeting point of the M1 and M2 trunks as an objective, g...

journal_title：Neurosurgery

authors： Elsharkawy A,Lehečka M,Niemelä M,Billon-Grand R,Lehto H,Kivisaari R,Hernesniemi J

更新日期：2013-07-01 00:00:00

abstract：OBJECTIVE:To identify factors predictive of postoperative lower cranial nerve palsy (LCNP) among patients undergoing surgery for vertebral artery (VA)- posteroinferior cerebellar artery (PICA) aneurysms. The natural history of this LCNP is defined, and its effect on postoperative patient course is analyzed. No similar ...

journal_title：Neurosurgery

authors： Al-khayat H,Al-Khayat H,Beshay J,Manner D,White J

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:To demonstrate the technique of stereotactic microsurgical endoscopic removal of intraventricular tumors or colloid cysts assisted by intraoperative computed tomography. METHODS:We adapted a tubular "ventriculoport" for stereotactic insertion of an endoscope into the ventricle. This facilitated microsurgical...

journal_title：Neurosurgery

authors： Harris AE,Hadjipanayis CG,Lunsford LD,Lunsford AK,Kassam AB

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Epilepsy surgery involving the cingulate gyrus has been mostly presented as case reports, and larger series with long-term follow-up are not published yet. OBJECTIVE:To report our experience with focal epilepsy arising from the cingulate gyrus and surrounding structures and its surgical treatment. METHODS:...

journal_title：Neurosurgery

authors： von Lehe M,Wagner J,Wellmer J,Clusmann H,Kral T

更新日期：2012-04-01 00:00:00

abstract：OBJECTIVE:Leptomeningeal gliomatosis (LG) is a clinically uncommon metastatic complication of high-grade gliomas (HGGs), for which there is no consensus regarding treatment. The goal of this study was to determine the toxicity and response rate of combined-modality therapy for the treatment of patients with HGGs and LG...

journal_title：Neurosurgery

authors： Chamberlain MC

更新日期：2003-02-01 00:00:00

abstract：OBJECTIVE:The majority of tumors of the cerebellopontine angle (CPA) are benign. We report the case of a primary malignant melanoma of the CPA that mimicked a vestibular schwannoma (acoustic neuroma). We discuss the differential diagnosis and prognosis of melanotic lesions at this location. CLINICAL PRESENTATION:A 49-...

journal_title：Neurosurgery

authors： Piedra MP,Scheithauer BW,Driscoll CL,Link MJ

更新日期：2006-07-01 00:00:00

abstract：OBJECTIVE:To stratify the risk of embolization during the treatment of cerebral arteriovenous malformations (AVMs) by grade and to assess its impact on the overall treatment risk. METHODS:Patients with cerebral AVMs treated with embolization between 1995 and 2004 were retrospectively reviewed. Age, sex, AVM grade, loc...

journal_title：Neurosurgery

authors： Kim LJ,Albuquerque FC,Spetzler RF,McDougall CG

更新日期：2006-07-01 00:00:00

abstract：OBJECTIVE:Interleukin-12 (IL-12) may be useful for immunotherapy against gliomas because it can reverse the glioma-induced suppression of T-cell proliferation and interferon-gamma production. We postulated that peripheral infusion of IL-12 along with irradiated tumor cells can lead to immunological rejection of 9L glio...

journal_title：Neurosurgery

authors： Jean WC,Spellman SR,Wallenfriedman MA,Hall WA,Low WC

更新日期：1998-04-01 00:00:00