Spurious sulfamethoxazole-trimethoprim resistance of Salmonella typhi.

Abstract:

:Several studies have identified thymidine excess in susceptibility test media as the cause of spurious resistance of various bacteria to sulfamethoxazole-trimethoprim. We document the phenomenon in Salmonella typhi and Salmonella paratyphi-A and demonstrate its occurrence in 3 of 17 (18%) lots of Mueller-Hinton agars now in use in major medical laboratories in Lima, Peru. The findings are particularly significant because sulfamethoxazole-trimethoprim is an important alternative to chloramphenicol or ampicillin for the treatment of typhoid and paratyphoid fevers.

journal_name

J Clin Microbiol

authors

Escamilla J,Kilpatrick ME,Ugarte HF

doi

10.1128/JCM.23.1.205-206.1986

subject

Has Abstract

pub_date

1986-01-01 00:00:00

pages

205-6

issue

1

eissn

0095-1137

issn

1098-660X

journal_volume

23

pub_type

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