The discovery of the HLA-B*56:75 allele shows that HLA sequencing is important in all transplant settings.

abstract：:Full-length sequences of HLA-B*56:01:01:01, B*56:03 and B*56:04, confirmed by cloning and sequencing in Chinese donors. ...

journal_title：HLA

authors： Li Z,Zou HY

更新日期：2017-04-01 00:00:00

abstract：:One nucleotide substitution at position 276 of HLA-B*52:01:01 results in a novel allele, HLA-B*52:70. ...

journal_title：HLA

authors： Mo XD,Wang J,Zhang T

更新日期：2017-10-01 00:00:00

abstract：:HLA-E, a class I nonclassical HLA molecule, is expressed in all tissues and is involved in the regulation of both innate (by interaction with the CD94/NKG2 receptor expressed mainly in NK cells) and adaptive immunity (by interaction with T CD8+ cells), suggesting a possible role in the solid organ transplantation cont...

journal_title：HLA

authors： de Miranda BLM,Gelmini GF,Risti M,Hauer V,da Silva JS,Roxo VMMS,Bicalho MDG,Malheiros D

更新日期：2020-05-01 00:00:00

abstract：:HLA-C*01:154 has a single nucleotide substitution at position 312 C > A when compared with HLA-C*01:02. ...

journal_title：HLA

authors： You X,Wang W,Zhang W,He J,Zhu F

更新日期：2020-05-01 00:00:00

abstract：:One nucleotide substitution at residue 476 of HLA-B*40:01:01 results in a new allele, HLA-B*40:326. ...

journal_title：HLA

authors： Yang KL,Hung JH,Lin PY

更新日期：2016-05-01 00:00:00

abstract：:HLA-DRB3*03:39 differs from HLA-DRB3*03:01:01 by a single nucleotide substitution in codon 22 (Glutamic acid to Lysine). ...

journal_title：HLA

authors： Jawdat D,Algharib R,Almusa A,Alaskar AS,Hajeer AH

更新日期：2020-07-01 00:00:00

abstract：:PCR-sequence-specific oligonucleotide (PCR-SSO) is commonly used for HLA-typing. We recently replaced LabType SSO HD kit for HLA-C typing with the XR kit (OneLambda, Inc.). We used 137 patients' samples representing unique most likely HLA-C allele combinations to compare these kits' performance. The XR kit decreased t...

journal_title：HLA

authors： Cargou M,Ralazamahaleo M,Blouin L,Guidicelli G,Visentin J

更新日期：2020-09-01 00:00:00

abstract：:B*35:460Q differs from B*35:03:01:01 by one nucleotide substitution at position 406 in exon 3. ...

journal_title：HLA

authors： Genebrier S,Elsermans V,Nivet C,Chérel M,Renac V

更新日期：2020-08-10 00:00:00

abstract：:HLA-B*13:69 allele differs from B*13:02:01 by one nucleotide substitution at position 628 from A to C. ...

journal_title：HLA

authors： Zheng JW,Xie JH,Sun Y,Jiang YQ,Xiang D

更新日期：2016-09-01 00:00:00

abstract：:HLA-DRB3*02:02:25 differs from HLA-DRB3*02:02:01:02 by one nucleotide substitution in codon 116 in exon 3. ...

journal_title：HLA

authors： Cargou M,Andreani M,Troiano M,Ralazamahaleo M,Visentin J

更新日期：2020-09-01 00:00:00

abstract：:Two new HLA alleles were identified during routine next generation sequencing. ...

journal_title：HLA

authors： Swelsen WTN,Tetar GC,Varlack SV,Matar A,Lardy NM

更新日期：2020-05-01 00:00:00

abstract：:MICA and MICB genes encode ligands that interact with the natural killer (NK) cell activating receptor, NKG2D. These ligands display a highly polymorphic allelic repertoire, although the true functional significance of this polymorphism remains elusive. We previously reported additional polymorphism in the 5' untransl...

journal_title：HLA

authors： Cox ST,Hernandez D,Danby R,Turner TR,Madrigal JA

更新日期：2018-12-01 00:00:00

abstract：:One nucleotide substitution in codon 127 of HLA-DQB1*03:01:01:07 results in the novel allele, HLA-DQB1*03:404. ...

journal_title：HLA

authors： Keppen C,Sharma A,Medhi S,Khamo V,Kanga U

更新日期：2020-01-01 00:00:00

abstract：:Genomic full-length sequence of HLA-A*11:172 was identified by a group-specific sequencing approach from China. ...

journal_title：HLA

authors： Xu YP,Yang H,Hong WX

更新日期：2018-10-01 00:00:00

abstract：:Identification of the novel HLA-C*14:02:34 allele that differs from HLA-C*14:02:01 at one position in exon 1. ...

journal_title：HLA

authors： Stelet VN,Cita RF,Mendes MF,Souza TL,Abdelhay E

更新日期：2020-11-01 00:00:00

abstract：:The single nucleotide polymorphisms (SNPs) rs11188513, rs7071836, rs10748643, rs9450279, rs4458647, and rs6922 map in the genes of ectonucleoside triphosphate diphosphohydrolase 1 (ENTPD1) and 5'-nucleotidase ecto. We investigated whether these SNPs and haplotypes of these SNPs are associated with an acute cellular re...

journal_title：HLA

authors： Thude H,Onken L,Kappauf J,Dworak M,Sterneck M,Peine S,Nashan B,Koch M

更新日期：2020-07-01 00:00:00

abstract：:One nucleotide substitution in codon 90 of HLA-C*16:02:01 results in a novel allele, HLA-C*16:46. ...

journal_title：HLA

authors： Jahromi M,Jacob SP,Taha N,Lin PY,Yang KL

更新日期：2020-01-01 00:00:00

abstract：:New HLA alleles found in the Finnish population: A*03:283N, A*68:167, C*03:327 and C*03:361. ...

journal_title：HLA

authors： Polvi A,Peräsaari J,Linjama T,Saarinen T,Koskela S,Voorter CEM,Jaatinen T

更新日期：2018-01-01 00:00:00

abstract：:The role of de novo donor-specific anti-human leukocyte antigen (anti-HLA) antibodies (dnDSA) within the pathways leading to graft failure remains not fully understood. We investigated 56 patients who were transplanted between 2002 and 2014 with kidney graft failure (cases), for a possible association of development o...

journal_title：HLA

authors： Castro A,Malheiro J,Tafulo S,Dias L,Martins LS,Fonseca I,Beirão I,Castro-Henriques A,Cabrita A

更新日期：2017-11-01 00:00:00

abstract：:One nucleotide substitution at residue 517 of HLA-A*11:01:01:01 results in a novel allele, HLA-A*11:231. ...

journal_title：HLA

authors： Yang KL,Hung JH,Lin PY

更新日期：2016-03-01 00:00:00

abstract：:The new HLA-B*39:01:01:04 allele differs from HLA-B*39:01:01 by a C → T substitution in intron 1. ...

journal_title：HLA

authors： Kwok J,Ho JC,Chan YS,Soormally A,Marsh SG

更新日期：2017-02-01 00:00:00

abstract：:Adverse drug reactions (ADR) can be broadly categorised as either on-target or off-target. On-target ADRs arise as a direct consequence of the pharmacological properties of the drug and are therefore predictable and dose-dependent. On-target ADRs comprise the majority (>80%) of ADRs, relate to the drug's interaction w...

journal_title：HLA

authors： Redwood AJ,Pavlos RK,White KD,Phillips EJ

更新日期：2018-01-01 00:00:00

abstract：:HLA-A*24:02:56 differs from A*24:02:01:01 by one nucleotide change at position 795 from C to T. ...

journal_title：HLA

authors： Lin FQ,Zhang X,Zhang B,Wu C,Li JP

更新日期：2018-01-01 00:00:00

abstract：:HLA-B*07:381 differs from B*07:02:01:01 by one nucleotide substitution at position 1046 in exon 7. ...

journal_title：HLA

authors： Genebrier S,Elsermans V,Texeraud E,Bertrand G,Renac V

更新日期：2020-12-01 00:00:00

abstract：:HLA-B*46:67 differs from HLA-B*46:01:01 in codons 94, 95, and 103 in exon 3. ...

journal_title：HLA

authors： Baek IC,Choi EJ,Shin DH,Kim HJ,Kim TG

更新日期：2018-11-01 00:00:00

abstract：:HLA-A*33:03:01:06 differs from HLA-A*33:03:01:01 by one nucleotide substitution (T- > C) in intron 3. ...

journal_title：HLA

authors： Sharma A,Tyagi S,Gautam SK,Abid M,Kanga U

更新日期：2019-12-01 00:00:00

abstract：:One nucleotide replacement at nucleotide 811 of HLA-A*02:01:01:01 results in a new allele, HLA-A*02:692. ...

journal_title：HLA

authors： Zhu YL,Han B,Chi XY,Hu B,Feng ZH

更新日期：2018-01-01 00:00:00

abstract：:There are several aspects of HLA-C gene expression that distinguish it from the HLA-A and HLA-B genes. First, HLA-C is expressed by extravillous trophoblasts, whereas HLA-A and HLA-B are not. Second, its cell-surface expression is much lower, which has been linked to changes in transcription and efficiency of peptide ...

journal_title：HLA

authors： Johnson JK,Wright PW,Li H,Anderson SK

更新日期：2018-11-01 00:00:00

abstract：:Two nucleotide changes in the 3'untranslated region of HLA-C*07:06:01:01 results in the novel allele, HLA-C*07:06:01:06. ...

journal_title：HLA

authors： Keppen C,Sharma A,Gautam SK,Khamo V,Kanga U

更新日期：2020-01-01 00:00:00

abstract：:A one nucleotide replacement in codon 261 of HLA-B*40:01:01 results in a novel allele, HLA-B*40:247. ...

journal_title：HLA

authors： Chang CL,Lin CY

更新日期：2017-08-01 00:00:00