Abstract:
BACKGROUND:In recent years, the incidence of IBS has gradually increased, and it is considered as one of the most common functional gastrointestinal diseases. However, the etiology of IBS is still unclear, and expectations are rising for more targeted treatments. Many clinical trials have explored the link between Helicobacter pylori (H pylori) and IBS, with different conclusions. Therefore, we conducted a meta-analysis to explore whether there is an association between H pylori and IBS, which is of great significance for targeted treatment of IBS. METHODS:We performed a systematic review and meta-analysis of the association between H pylori and IBS. We searched PubMed, EMBASE, Medline and the Cochrane Library to collect related studies. OR was used to describe the ratio of the probability of the H pylori infection occurring in IBS patients versus the controls. Heterogeneity was assessed by subgroup and meta-regression analysis. RESULTS:Eight studies, including 1861 patients, assessed the association between H pylori infection and IBS. The OR of H pylori in IBS patients compared to controls was 1.32 (95% CI: 0.94-1.87; P = 0.11). Subgroup analyses showed a difference between IBS patients diagnosed with Roman III criteria and those diagnosed with non-Roman III criteria. CONCLUSIONS:Our study suggests that H pylori may have a positive effect on the development of IBS. Although the differences were not statistically significant, there were significant differences among subgroups of patients. Considering the limitations and heterogeneity, high quality studies are needed to further explore the effect of H pylori on the development of IBS.
journal_name
Medicine (Baltimore)journal_title
Medicineauthors
Li C,Shuai Y,Zhou X,Chen Hdoi
10.1097/MD.0000000000022975subject
Has Abstractpub_date
2020-12-11 00:00:00pages
e22975issue
50eissn
0025-7974issn
1536-5964pii
00005792-202012110-00011journal_volume
99pub_type
杂志文章,meta分析相关文献
MEDICINE文献大全abstract:RATIONALE:Sclerosing osteomyelitis of Garré is a rare condition that occurs most commonly in tubular bones and the mandible. Its nontypical symptoms, low morbidity, and insidious process make its diagnosis difficult at an early stage. In this article, we reported a case of chronic sclerosing osteomyelitis which occurre...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000008692
更新日期:2017-11-01 00:00:00
abstract::Human immunodeficiency virus (HIV) disclosure is a prerequisite to get access to antiretroviral therapy (ART) and social support. Increased disclosure of HIV status has been shown to reduce mother-to-child transmission and high-risk sexual behaviors. Limited studies were conducted to get an insight into HIV disclosure...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000016681
更新日期:2019-08-01 00:00:00
abstract::A retrospective study of consecutive patients.The purpose of this study was to compare the clinical effect of biomimetic mineralized collagen (MC) modified polymethylmethacrylate (PMMA) bone cement and traditional PMMA bone cement for the treatment of osteoporotic vertebral compression fractures (OVCF).New fracture on...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000012204
更新日期:2018-09-01 00:00:00
abstract::In the absence of liver biopsy and transient elastography (TE), aspartate aminotransferase to platelet ratio (APRI), fibrosis-4 score (FIB-4), and gammaglutamyl transpeptidase to platelet ratio (GPR) are simple and inexpensive methods for the detection of liver fibrosis. AIMS:We compared the performance of APRI, FIB-...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000018038
更新日期:2019-12-01 00:00:00
abstract::To investigate relevant factors and patients with acute myocardial infarction (AMI) were admitted during between weekdays and weekends period.Retrospective population-based study setting: from the 2005 population-based national health insurance underwriting database of millions of people, random sampling (National Hea...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000013883
更新日期:2019-01-01 00:00:00
abstract::The direction-changing bilateral gaze-evoked nystagmus (GEN) (BGEN) is a more specific sign for a gaze-holding deficit than unilateral GEN (UGEN) in a central lesion. We sought to clarify which cerebellar structure is responsible for the generation of BGEN compared with UGEN.We studied 47 cases of UGEN or BGEN associa...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000019866
更新日期:2020-04-01 00:00:00
abstract::Advanced gastric cancer has a poor prognosis because of advanced gastric cancer is prone to metastasis. It is urgent for us to find an indicator to predict the prognosis of gastric cancer in a timely fashion. Research has revealed that inflammation has an important role in predicting survival in some cancers. The purp...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000019405
更新日期:2020-03-01 00:00:00
abstract:BACKGROUND:Hyperlipidemia has been a root cause of atherosclerosis, which leads to a high risk to serious cardio-cerebrovascular disease. Many trials have reported that moxibustion therapy is effective in lowering blood lipid levels when treating hyperlipidemia. The aim of this systematic review is to assess the effect...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000018209
更新日期:2019-11-01 00:00:00
abstract::Laparoscopic inguinal herniorrhaphy has been well established for the management of primary and recurrent inguinal hernias. Single-incision laparoscopic surgery (SILS) has now been accepted as a less invasive alternative to conventional laparoscopic surgery. However, commercially available access devices for SILS had ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000021787
更新日期:2020-08-21 00:00:00
abstract:RATIONALE:Hyponatremia occurs frequently in the hospital setting and may be attributable to a host of etiologies. Drugs are frequently implicated. Trimethoprim-sulfamethoxazole (TMP/SMX) represents a well-recognized pharmacologic precipitant of drug-induced hyponatremia, with several reports extant in the retrievable l...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000020746
更新日期:2020-08-14 00:00:00
abstract:BACKGROUND:Surgical resection is shown to present the best chance of cure in the treatment of intrahepatic cholangiocarcinoma (ICC). However, the appropriate length of the negative margin remains unclear. The aim of the present meta-analysis was to investigate whether a clear margin of 10 mm or more (≥10 mm) conferred ...
journal_title:Medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1097/MD.0000000000004621
更新日期:2016-08-01 00:00:00
abstract:RATIONALE:Acquired vertical diplopia is commonly observed in trochlear nerve palsy, often resulting from blunt head trauma or vascular problems. It is rarely caused by tumorous conditions or space occupying lesion. We report the first case of Onodi cell mucocele causing isolated trochlear nerve palsy. PATIENT CONCERNS...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000015475
更新日期:2019-05-01 00:00:00
abstract::Nocardia is a ubiquitous environmental pathogen that causes infection primarily following inhalation into the lungs. It is generally thought to cause infection primarily in immunocompromised patients, but nonimmunocompromised individuals are also at risk of infection. We sought to compare risk factors, clinical manife...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000012436
更新日期:2018-10-01 00:00:00
abstract:RATIONALE:Pulmonary hyalinizing granuloma (PHG) is a rare benign disease that has been shown to be associated with the deposition of immune complexes in the lung parenchyma caused by infection or autoimmune diseases. There have been no reports of PHG in association with immunoglobulin A nephropathy (IgAN). PATIENT CON...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000009088
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND:To comprehensively evaluate the treatment efficacy and safety of silymarin for patients with glucose/lipid metabolic dysfunction using a meta-analysis. METHODS:A systematic literature search in PubMed, EMBASE and Cochrane Library databases was performed up to October 1, 2019. STATA 13.0 software was used to...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000022249
更新日期:2020-10-02 00:00:00
abstract::Patients with "difficult-to-treat" advanced testicular cancer can require multiple therapies. We retrospectively assessed our patients with advanced germ cell tumors (GCTs) and characterized the clinical efficacy, outcomes, and factors affecting overall survival (OS).Two hundred fifty-three patients with advanced GCTs...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000000653
更新日期:2015-03-01 00:00:00
abstract:BACKGROUND:Readmission is a common postoperative adverse event. This study aimed to analyze potential risk factors for the incidence of postoperative 30-day readmission after discharge for gastric cancer patients with surgical treatment. METHODS:Those studies that reported the risk factors of gastric cancer patients w...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000014639
更新日期:2019-03-01 00:00:00
abstract::The purpose of the current study was to investigate the characteristics of patients with diabetic nephropathy (DN) without diabetic retinopathy (DR).One hundred four patients with biopsy-proven DN, and 52 patients with diabetes mellitus (DM) without DR who were diagnosed as membranous nephropathy by renal biopsy were ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000006805
更新日期:2017-05-01 00:00:00
abstract::This is an observational study to determine the most relevant parameter of ¹⁸F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) for predicting recurrence in cervical cancer. Fifty-six patients with International Federation of Gynecology and Obstetrics (FIGO) stage IIB-IVA cervical can...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000002992
更新日期:2016-03-01 00:00:00
abstract::The aim of the present study was to assess the effect of Endostar and temozolomide or dacarbazine plus 5-fluorouracil (5-FU) in patients with advanced pancreatic neuroendocrine tumors (pNETs).Phase II study of 14 patients with locally advanced or metastatic well-differentiated pNETs treated between April 2013 and Sept...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000012750
更新日期:2018-11-01 00:00:00
abstract::Premature ventricular complexes are very common, appearing most frequently in patients with hypertension, obesity, sleep apnea, and structural heart disease. Sympathetic hyperactivity plays a critical role in the development, maintenance, and aggravation of ventricular arrhythmias. Recently, Armaganijan et al reported...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000002287
更新日期:2015-12-01 00:00:00
abstract:BACKGROUD:The aim of the study was to evaluate the effect of early parenteral iron supplementation combined erythropoietin for prevention of anemia in preterm infants. METHODS:In total, 96 preterm infants were randomly assigned to 3 groups: a control group receiving standard parenteral nutrition (group 1: n = 31), an ...
journal_title:Medicine
pub_type: 杂志文章,随机对照试验
doi:10.1097/MD.0000000000005795
更新日期:2017-03-01 00:00:00
abstract::Immunotherapy with Bacillus Calmette-Guérin (BCG) is the most efficacious treatment for high-risk bladder cancer (BC) (Ta/T1 or carcinoma in situ) to reduce the risk of recurrence. Our aim was to evaluate whether hypertension and diabetes influence the outcome of patients with noninvasive BC treated with BCG instillat...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000000589
更新日期:2015-03-01 00:00:00
abstract:RATIONALE:Spontaneous and repeated hepatic ruptures caused by hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome are uncommon but life-threatening conditions that rarely occur early in the second trimester of pregnancy. PATIENT CONCERNS:We describe a patient who experienced spontaneous hepatic ruptu...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000011458
更新日期:2018-07-01 00:00:00
abstract::Congenital heart disease (CHD) is the most commonly diagnosed congenital disorder in newborns. The incidence and mortality of CHD vary worldwide. A detailed understanding of the global, regional, and national distribution of CHD is critical for CHD prevention.We collected the incidence and mortality data of CHD from t...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000020593
更新日期:2020-06-05 00:00:00
abstract::Occipitalization of atlas (OA) is a congenital disease with the possibility of anomalous bony anatomies and the C2 pedicle screw insertion is technically challenging. However, there are no existing literatures clarified the dimensions and angulations of the C2 pedicles, lamina and lateral masses for screw insertion in...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001492
更新日期:2015-09-01 00:00:00
abstract:BACKGROUND:Nowadays, psychiatric morbidities are more and more common, which imposes huge social and economic burden on all countries across the world. Mental illnesses are found to be related to genetics. Over the past few years, a large number of risk genes and loci related to psychiatric morbidities have been report...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000022875
更新日期:2020-11-06 00:00:00
abstract:RATIONALE:The precise cause of granulomatosis with polyangiitis (GPA) remains unclear. Herein we present a case of refractory GPA occurring after trauma. PATIENT CONCERNS:A 43-year-old man suffered fractures of the left orbital in an accident, and then received surgical repair. At a postoperative follow-up, he develop...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000014189
更新日期:2019-01-01 00:00:00
abstract:INTRODUCTION:Chronic active Epstein-Barr virus (EBV) infection (CAEBV) is characterized as chronic or recurrent mononucleosis-like symptoms and elevated EBV deoxyribonucleic acid (EBV-DNA) copies. Cardiovascular complications have high morbidity and mortality. The treatment regimen for CAEBV has not been established ye...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/MD.0000000000004384
更新日期:2016-08-01 00:00:00
abstract:BACKGROUND:Congenital auricular deformities (CAD) are prevalent worldwide. The objective of this study is to investigate the effectiveness and safety of ear molding for children with CAD at their early days. METHODS:One hundred and nighty children (under 3 days) with CAD will be included in the study. Participants wil...
journal_title:Medicine
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1097/MD.0000000000021313
更新日期:2020-07-24 00:00:00