Anatomical structure responsible for direction changing bilateral gaze-evoked nystagmus in patients with unilateral cerebellar infarction.

Abstract:

:The direction-changing bilateral gaze-evoked nystagmus (GEN) (BGEN) is a more specific sign for a gaze-holding deficit than unilateral GEN (UGEN) in a central lesion. We sought to clarify which cerebellar structure is responsible for the generation of BGEN compared with UGEN.We studied 47 cases of UGEN or BGEN associated with isolated unilateral cerebellar infarction in the territories of the cerebellar arteries diagnosed by brain magnetic resonance image (MRI) from June 2007 to April 2014. To identify the structures involved in the generation of BGEN, the overlapped lesions of the BGEN group were subtracted from those of UGEN group and vice versa.About half of the patients (25/47, 53%) showed BGEN and others showed UGEN. There was no difference in the interval from symptom onset to examination between 2 groups (1.3 days vs 2.5 days, P = .24). Thirty-five patients (35/47, 75%) with GEN also showed spontaneous nystagmus. Lesion subtraction analyses revealed that both of the patients with BGEN and UGEN had damage around the vermal pyramid, the uvula and the tonsil, parts of the biventer lobule, and the inferior semilunar lobule.Midline and lower cerebellar structures are related to both BGEN and UGEN in patients with unilateral cerebellar infarction. Regardless of unilateral or bilateral, GEN may represent damage of the gaze-holding neural integrator control system in human.

journal_name

Medicine (Baltimore)

journal_title

Medicine

authors

Lee H,Kim HA

doi

10.1097/MD.0000000000019866

subject

Has Abstract

pub_date

2020-04-01 00:00:00

pages

e19866

issue

17

eissn

0025-7974

issn

1536-5964

pii

00005792-202004240-00061

journal_volume

99

pub_type

杂志文章

相关文献

MEDICINE文献大全
  • Rickettsialpox: report of an outbreak and a contemporary review.

    abstract::Rickettsialpox is a mild illness characterized by the appearance of a primary eschar at the site of a mite bite followed by fever, headache, and a papulovesicular rash. It can be confused with a variety of illnesses including several other rickettsial diseases and chickenpox. R. akari, the etiologic agent, is a ricket...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/00005792-198109000-00004

    authors: Brettman LR,Lewin S,Holzman RS,Goldman WD,Marr JS,Kechijian P,Schinella R

    更新日期:1981-09-01 00:00:00

  • Diversity analysis of subgingival microbial bacteria in peri-implantitis in Uygur population.

    abstract::This study is to investigate the subgingival bacterial diversity and community structure in the Uygur subjects with peri-implantitis.Totally 40 cases of gingival crevicular fluid were collected from Uygur subjects and divided into the Control group (healthy implants) and Case group (peri-implantitis), respectively. DN...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000009774

    authors: Gao X,Zhou J,Sun X,Li X,Zhou Y

    更新日期:2018-02-01 00:00:00

  • Heterogeneity of T3 stage esophageal squamous cell carcinoma in different parts based on enhanced CT radiomics.

    abstract::Esophageal cancer is a common malignant tumor of the digestive system with a high incidence and a poor prognosis. At the present, CT-based radiomics is providing more and more valuable information. However, the heterogeneity of the study and the poor repeatability of the texture feature parameters have limited its wid...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000021470

    authors: Li XF,Wang Q,Duan SF,Yao B,Liu CY

    更新日期:2020-08-07 00:00:00

  • Removal of the root canal smear layer using Carisolv III and sodium hypochlorite.

    abstract::The present study investigated the effectiveness of a Carisolv III + 0.5% sodium hypochlorite (NaOCl)-based root canal irrigant for smear layer removal.Forty maxillary incisors were randomly divided into 4 groups (n = 10 per group). The canals in group A (experimental) were prepared with 0.5% NaOCl, and Carisolv III a...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000020372

    authors: Wu D,Ma YZ,Jia J,Xin BC,Wang DS,Sun DG,Wang LX

    更新日期:2020-05-29 00:00:00

  • Pancreaticopleural and pancreaticomediastinal fistula extending to the cervical region, with dysphagia as initial symptom: A case report.

    abstract:RATIONALE:Pancreaticopleural and pancreaticomediastinal fistulas are rare complications of pancreatitis. They are often misdiagnosed and there are no strict guidelines of treatment. In this study, we present a brief report of a combined pancreaticopleural and pancreaticomediastinal fistula extending to the cervical reg...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000014233

    authors: Grudzińska E,Pilch-Kowalczyk J,Kuśnierz K

    更新日期:2019-02-01 00:00:00

  • Corrective osteotomy with retrograde Fassier-Duval nail in an osteogenesis imperfecta patient with bilateral genu valgum: A case report.

    abstract:RATIONALE:The treatment of osteogenesis imperfecta (OI) requires a multidisciplinary approach to maximize function and reduce fracture incidence. The aim of this case report was to discuss an alternative surgical approach to stabilize a corrective osteotomy using the Fassier Duval (FD) system in an OI patient. PATIENT...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000008459

    authors: Lin TY,Yang CY,Liu SC

    更新日期:2017-11-01 00:00:00

  • Montelukast and budesonide combination for children with chronic cough-variant asthma.

    abstract::This study investigated the effectiveness and safety of montelukast combined budesonide (MCB) treatment for children with chronic cough-variant asthma (CCVA).In total, 82 cases of children with CCVA, aged 4 to 11 years were included in this study. All cases received either MCB or budesonide alone between May 2015 and ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000011557

    authors: Wang XP,Yang LD,Zhou JF

    更新日期:2018-07-01 00:00:00

  • Analysis of cervical human papillomavirus infection in 2300 women in Urumqi, China.

    abstract::This study is to investigate the cervical human papillomavirus (HPV) infection rate in women of Urumqi, China.The epidemiological questionnaire survey was used to study 2300 women in Urumqi with a prospective research method. The second-generation hybrid capture assay, cervical liquid-based cytology test, colposcopy, ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000013206

    authors: Yao L,Yuan M,Yuan J,Zhou P,Mei L,Cheng J

    更新日期:2018-11-01 00:00:00

  • Triglyceride glucose-body mass index is effective in identifying nonalcoholic fatty liver disease in nonobese subjects.

    abstract::Nonalcoholic fatty liver disease (NAFLD) is an increasingly common condition that is highly correlated with obesity; however, it is not uncommon among nonobese individuals. Triglyceride (TG) and glucose index combined with body mass index (TyG-BMI) has been proposed as a favorable marker of insulin resistance. We soug...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000007041

    authors: Zhang S,Du T,Li M,Jia J,Lu H,Lin X,Yu X

    更新日期:2017-06-01 00:00:00

  • Establishing a new formula for estimating renal depth in a Chinese adult population.

    abstract::We aimed to establish a new formula for estimating renal depth, based on anthropometric variables, and to compare the estimates with actual data from a group of living kidney donors undergoing computed tomography angiography (CTA).Renal depths in 167 living kidney donors were measured by CTA. Regression analysis was u...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000005940

    authors: Xue J,Deng H,Jia X,Wang Y,Lu X,Ding X,Li Q,Yang A

    更新日期:2017-02-01 00:00:00

  • Effect of extracorporeal shock-wave therapy for treating patients with chronic rotator cuff tendonitis.

    abstract:BACKGROUND:This study aimed to determine the efficacy and safety of extracorporeal shock-wave therapy (ESWT) for treating patients with chronic rotator cuff tendonitis (CRCT). METHODS:In this study, 84 patients with CRCT were randomly divided into intervention and control groups in a ratio of 1:1. Patients in the inte...

    journal_title:Medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/MD.0000000000007940

    authors: Li W,Zhang SX,Yang Q,Li BL,Meng QG,Guo ZG

    更新日期:2017-09-01 00:00:00

  • Effect of dexmedetomidine added to ropivicaine for caudal anesthesia in patients undergoing hemorrhoidectomy: A prospective randomized controlled trial.

    abstract:BACKGROUND:To assess the effect of dexmedetomidine added to ropivaccaine on the onset and duration of sensory block, as well as postoperative analgesia during caudal anesthesia in patients undergoing hemorrhoidectomy. METHODS:Fifty adult patients scheduled for hemorrhoidectomy were divided into 2 groups. The group R r...

    journal_title:Medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/MD.0000000000011731

    authors: Xu D,Xiu M,Zhang X,Zhu P,Tian L,Feng J,Wu Y,Zhao Z,Luan H

    更新日期:2018-08-01 00:00:00

  • Inflammatory demyelinating neuropathies with focal segmental glomerulosclerosis: Two case reports.

    abstract:RATIONALE:Inflammatory demyelinating neuropathies such as Guillain-Barré syndrome (GBS), chronic inflammatory demyelinating polyneuropathy (CIDP), and focal segmental glomerulosclerosis (FSGS) are autoimmune disorders that may have a common pathogenesis. Here, we describe 2 unique cases of FSGS, 1 with GBS and the othe...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000013304

    authors: Mao Y,Zhang M,Liu S,Xu Y,Xue J,Hao C,Lai L

    更新日期:2018-12-01 00:00:00

  • Complications associated with Brucella melitensis infection: a study of 530 cases.

    abstract::We carried out a prospective study of 530 patients older than 14 years of age with brucellosis. We describe the incidence and clinical features of the focal forms of the disease, analyzing some of the possible factors associated with their appearance. One hundred sixty-nine patients (31.9%) had a focal form or complic...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/00005792-199607000-00003

    authors: Colmenero JD,Reguera JM,Martos F,Sánchez-De-Mora D,Delgado M,Causse M,Martín-Farfán A,Juárez C

    更新日期:1996-07-01 00:00:00

  • External fixation combined with delayed internal fixation in treatment of tibial plateau fractures with dislocation.

    abstract::The aim of this study was to evaluate the clinical efficacy of external fixation, delayed open reduction, and internal fixation in treating tibial plateau fracture with dislocation.Clinical data of 34 patients diagnosed with tibial plateau fracture complicated with dislocation between January 2009 and May 2015 were re...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000008221

    authors: Tao X,Chen N,Pan F,Cheng B

    更新日期:2017-10-01 00:00:00

  • The Lemierre syndrome: suppurative thrombophlebitis of the internal jugular vein secondary to oropharyngeal infection.

    abstract::We present 2 cases of the Lemierre syndrome (also called postanginal septicemia), along with 36 other cases from a review of recent literature. A review of the literature during the preantibiotic era is also included. This disease is caused by an acute oropharyngeal infection with secondary thrombophlebitis of the int...

    journal_title:Medicine

    pub_type: 杂志文章,评审

    doi:

    authors: Sinave CP,Hardy GJ,Fardy PW

    更新日期:1989-03-01 00:00:00

  • Treatment of distal radioulnar joint dislocation with spontaneous rupture of extensor tendon by Sauve-Kapandji osteotomy assisted by wrist arthroscopy: A case series and literature review.

    abstract:RATIONALE:Dislocation of the distal radioulnar joint and injury to distal forearm are commonly encountered. However, delayed diagnosis or misdiagnosis has been relatively rare due to improved diagnosis and treatment. Treatment of old dislocation of radioulnar joint is challenging due to development of secondary chronic...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000010752

    authors: Qian H,Chen G,Liu Z

    更新日期:2018-06-01 00:00:00

  • Association of human serotonin receptor 4 promoter methylation with autism spectrum disorder.

    abstract::Human serotonin receptor 4 (HTR4) encodes a 5-HT4 receptor involved in learning, memory, depression, anxiety, and feeding behavior. The aim of this study was to investigate the association between the deoxyribonucleic acid (DNA) methylation of HTR4 promoter and autism spectrum disorder (ASD), a disease characterized b...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000018838

    authors: Hu Z,Ying X,Huang L,Zhao Y,Zhou D,Liu J,Zhong J,Huang T,Zhang W,Cheng F,Duan S

    更新日期:2020-01-01 00:00:00

  • Short and long-term efficacy of massage for functional constipation: A protocol for systematic review and meta analysis.

    abstract:BACKGROUND:Functional constipation (FC) is one of the most common diseases throughout the world, which brings a bad influence on life quality as well as mental health. Massage has been widely used in the treatment of functional constipation in china. In several randomized controlled trials indicate that massage has a p...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000020698

    authors: Tang Y,Shi K,He F,Li M,Wen Y,Wang X,Zhu J,Jin Z

    更新日期:2020-06-19 00:00:00

  • Diagnostic Performance of Diffusion-weighted Magnetic Resonance Imaging in Bone Malignancy: Evidence From a Meta-Analysis.

    abstract::Current state-of-the-art nuclear medicine imaging methods (such as PET/CT or bone scintigraphy) may have insufficient sensitivity for predicting bone tumor, and substantial exposure to ionizing radiation is associated with the risk of secondary cancer development. Diffusion-weighted MRI (DW-MRI) is radiation free and ...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/MD.0000000000001998

    authors: Liu LP,Cui LB,Zhang XX,Cao J,Chang N,Tang X,Qi S,Zhang XL,Yin H,Zhang J

    更新日期:2015-11-01 00:00:00

  • Use of susceptibility-weighted imaging in assessing ischemic penumbra: A case report.

    abstract:RATIONALE:The ischemic penumbra assessment is essential for the subsequent therapy and prediction of evolution in patients with acute ischemic infraction. Although controversial as a perfect equivalence to penumbra, perfusion-weighted imaging (PWI)-diffusion-weighted imaging (DWI) mismatch may predict the response to t...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000006091

    authors: Wu X,Luo S,Wang Y,Chen Y,Liu J,Bai J,Feng J,Zhang H

    更新日期:2017-02-01 00:00:00

  • Use of the SYNTAX Score II to predict mortality in interventional cardiology: A systematic review and meta-analysis.

    abstract:BACKGROUND:As the SYNTAX Score has limitations, it should be replaced by another better angiographic tool. By comparing mortality that was observed following percutaneous coronary intervention (PCI) in patients who were allotted a low versus a high score, we aimed to systematically investigate mortality prediction usin...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000014043

    authors: Yang H,Zhang L,Xu CH

    更新日期:2019-01-01 00:00:00

  • A Case Report of Locked-in Syndrome Due to Bilateral Vertebral Artery Dissection After Cervical Spine Manipulation Treated by Arterial Embolectomy.

    abstract::Cervical spine manipulation (CSM) is a commonly spinal manipulative therapies for the relief of cervical spine-related conditions worldwide, but its use remains controversial. CSM may carry the potential for serious neurovascular complications, primarily due to vertebral artery dissection (VAD) and subsequent vertebro...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000002693

    authors: Ke JQ,Yin B,Fu FW,Shao SM,Lin Y,Dong QQ,Wang XT,Zheng GQ

    更新日期:2016-02-01 00:00:00

  • Magnetic stimulation for female patients with stress urinary incontinence, a meta-analysis of studies with short-term follow-up.

    abstract:BACKGROUND:To determine the efficacy of magnetic stimulation (MS) in female patients with stress urinary incontinence (SUI) by performing a meta-analysis on peer-reviewed randomized controlled trails (RCTs). METHODS:PubMed, Embase, and Cochrane library were retrieved for any peer-reviewed original articles in English....

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000015572

    authors: Peng L,Zeng X,Shen H,Luo DY

    更新日期:2019-05-01 00:00:00

  • Ki-67 labeling index is a predictive marker for a pathological complete response to neoadjuvant chemotherapy in breast cancer: A meta-analysis.

    abstract:BACKGROUND:A pathological complete response (pCR) after neoadjuvant chemotherapy (NCT) is a strong indicator of the benefit of therapy and presents an early surrogate for a favorable long-term outcome. It remains unclear whether Ki-67, a marker for tumor proliferation, can function as a predictor of the response to NCT...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/MD.0000000000009384

    authors: Tao M,Chen S,Zhang X,Zhou Q

    更新日期:2017-12-01 00:00:00

  • Risk factors for osteoporosis in liver cirrhosis patients measured by transient elastography.

    abstract::Osteoporosis or osteopenia is a common complication in patients with cirrhosis, but little is known about the risk factors for the occurrence of osteoporosis.Patients with liver cirrhosis due to chronic virus infection and alcoholic abuse were enrolled. Bone mineral density (BMD) was determined using dual-energy x-ray...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000010645

    authors: Zheng JP,Miao HX,Zheng SW,Liu WL,Chen CQ,Zhong HB,Li SF,Fang YP,Sun CH

    更新日期:2018-05-01 00:00:00

  • Hypokalemic Paralysis Complicated by Concurrent Hyperthyroidism and Chronic Alcoholism: A Case Report.

    abstract::Thyrotoxic periodic paralysis (TPP) is characterized by the presence of muscle paralysis, hypokalemia, and hyperthyroidism. We report the case of a young man with paralysis of the lower extremities, severe hypokalemia, and concurrent hyperthyroidism. TPP was suspected; therefore, treatment consisting of judicious pota...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000001689

    authors: Tsai MH,Lin SH,Leu JG,Fang YW

    更新日期:2015-09-01 00:00:00

  • Malignant pulmonary embolism associated with renal sarcoma: A case report.

    abstract:RATIONALE:The preoperative diagnosis of massive pulmonary tumor embolism associated with renal neoplasms is relatively rare. In most cases, pulmonary tumor embolism is detected intraoperatively during renal tumor resection. Moreover, primary renal sarcoma is rare, and primary renal sarcoma complicated by pulmonary tumo...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000019943

    authors: Yang JH,Song DH,Lee C,Kang DH,Jung JJ,Kim SH,Byun JH,Kim JW,Moon SH

    更新日期:2020-05-01 00:00:00

  • Bevacizumab with preoperative chemotherapy versus preoperative chemotherapy alone for colorectal cancer liver metastases: a retrospective cohort study.

    abstract::This study aimed to assess the efficacy and safety of bevacizumab plus preoperative chemotherapy as first-line treatment for liver-only metastatic colorectal cancer in Chinese patients compared with those of preoperative chemotherapy alone.Patients with histologically confirmed liver-only metastatic colorectal cancer ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000004767

    authors: Lu ZH,Peng JH,Wang FL,Yuan YF,Jiang W,Li YH,Wu XJ,Chen G,Ding PR,Li LR,Kong LH,Lin JZ,Zhang RX,Wan DS,Pan ZZ

    更新日期:2016-08-01 00:00:00

  • Validation of the mortality in emergency department sepsis (MEDS) score in a Singaporean cohort.

    abstract::The emergency department (ED) serves as the first point of hospital contact for most septic patients. Early mortality risk stratification using a quick and accurate triage tool would have great value in guiding management. The mortality in emergency department sepsis (MEDS) score was developed to risk stratify patient...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000016962

    authors: Pong JZ,Koh ZX,Samsudin MI,Fook-Chong S,Liu N,Ong MEH

    更新日期:2019-08-01 00:00:00