Oral mucosa lesions as atypical manifestation of adult-onset Still's disease.

Abstract:

:Adult-onset Still's disease is a systemic inflammatory disorder of unknown etiology, characterized by skin rash, spiking fever, arthralgias or arthritis, and leukocytosis. The typical skin rash is evanescent, salmon-pink, nonpruritic and maculopapular, predominantly on the extremities. It is considered one of the major Yamaguchi's criteria in adult-onset Still's disease. However, atypical skin lesions are also described. Here, a 61-year-old woman with sore throat, spiking fever, polyarthritis and evanescent salmon-pink nonpruritic maculopapular skin rash on the extremities was diagnosed with adult-onset Still's disease. In addition, atypical brown macules on oral mucosa, localized on the inner lips and tongue were also observed. Biopsy revealed a neutrophilic infiltrate. Despite treatment and improvement of the adult-onset Still's disease, the atypical oral mucosal lesions persisted.

journal_name

An Bras Dermatol

authors

Brance ML,Neffen EL

doi

10.1590/abd1806-4841.20186836

subject

Has Abstract

pub_date

2018-01-01 00:00:00

pages

271-273

issue

2

eissn

0365-0596

issn

1806-4841

pii

S0365-0596(20)30412-8

journal_volume

93

pub_type

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