Abstract:
Background:Our study assessed the reliability of non-gated, non-contrast chest computed tomography (NCCT) (with high pitch, wide coverage, and fast gantry rotation time, reconstructed at various slice thicknesses), compared with the electrocardiography (ECG)-gated calcium scoring cardiac computed tomography (CaCT), for quantifying coronary artery calcification (CAC). Methods:Patients aged ≥50 years who required clinical NCCT were prospectively enrolled. All CT scans were performed with 256-detector rows; z-axis coverage, 8 cm; pitch, 1.5; and gantry rotation time, 280 ms (table feed, 42.86 cm/s). NCCT was followed by ECG-gated CaCT. The NCCT images were reconstructed at 0.625-, 1.25-, and 2.5-mm slice intervals. The CAC score was calculated on four sets of CT images with a commercially available software using the Agatston method. The CAC scores were divided into four standard Agatston scoring categories (Agatston scores: 0, 1-100, 101-400, and >400). The inter-observer and inter-technique agreements were evaluated for the CAC scores. Results:Twenty-six patients (M:F, 14:12; mean age, 66.04±6.97 years) were evaluated. Agatston scores showed near-perfect correlation between CaCT and NCCT for each slice thickness. On Bland-Altman analysis, the mean differences of Agatston scores between CaCT and NCCT (slice thicknesses: 0.625, 1.25, and 2.5 mm) were 37.54, 6.67, and -41.04, respectively. Inter-technique concordance was high for the four Agatston scoring categories with linear-weighted kappa values of 0.599, 0.609, and 0.597 for NCCT (slice thicknesses: 0.625, 1.25, and 2.5 mm, respectively). NCCT with 1.25-mm slice thickness showed the strongest correlation with CaCT. Conclusions:CAC quantification with NCCT using a wide detector, high pitch, and high temporal resolution scanning modes correlates very highly with ECG-gated CaCT, and 1.25-mm slice thickness NCCT images are more reliable than other NCCT images.
journal_name
J Thorac Disjournal_title
Journal of thoracic diseaseauthors
Shin JM,Kim TH,Kim JY,Park CHdoi
10.21037/jtd-20-1371subject
Has Abstractpub_date
2020-10-01 00:00:00pages
5783-5793issue
10eissn
2072-1439issn
2077-6624pii
jtd-12-10-5783journal_volume
12pub_type
杂志文章abstract:Background:Tumor size of 8 cm or greater is a risk factor for recurrence after thymoma resection, but the role of induction therapy for large thymomas is not well defined. This study tested the hypothesis that induction therapy for thymomas 8 cm and larger improves survival. Methods:The use of induction therapy for pa...
journal_title:Journal of thoracic disease
pub_type: 杂志文章
doi:10.21037/jtd.2020.02.63
更新日期:2020-04-01 00:00:00
abstract::Cerebral oximetry based on near-infrared spectroscopy (NIRS) is increasingly used during the perioperative period of cardiovascular operations. It is a noninvasive technology that can monitor the regional oxygen saturation of the frontal cortex. Current literature indicates that it can stratify patients preoperatively...
journal_title:Journal of thoracic disease
pub_type: 杂志文章,评审
doi:10.3978/j.issn.2072-1439.2013.10.22
更新日期:2014-03-01 00:00:00
abstract::Cone beam computed tomography (CBCT) is a well-established imaging modality with numerous proven applications across multiple clinical disciplines. More recently, CBCT has emerged as an important imaging tool for bronchoscopists, primarily used during transbronchial biopsy of peripheral pulmonary lesions (PPLS). For t...
journal_title:Journal of thoracic disease
pub_type: 杂志文章,评审
doi:10.21037/jtd-20-2382
更新日期:2020-12-01 00:00:00
abstract:BACKGROUND:A retrospective analysis of patients undergoing cancer surgery suggested that using local anesthetics could reduce cancer recurrence and improve survival rate. Previous studies have indicated that local anesthetics may induce apoptosis in several kinds of cells in vitro, but the mechanism is unclear. METHOD...
journal_title:Journal of thoracic disease
pub_type: 杂志文章
doi:10.21037/jtd.2016.09.66
更新日期:2016-10-01 00:00:00
abstract:Background:Pulmonary metastasectomy (PM) has commonly been performed in patients with controlled metastatic sarcoma. We reviewed our single-institution experience with pulmonary resections for sarcoma to analyse clinical outcome and to identify prognostic factors associated with patient survival. Methods:All sarcoma p...
journal_title:Journal of thoracic disease
pub_type: 杂志文章
doi:10.21037/jtd.2019.08.10
更新日期:2019-08-01 00:00:00
abstract::Congenital pulmonary agenesis is a rare condition with high mortality. Mechanical ventilation in these patients is challenging and there has no such case been reported in the literature. We reported a 61-year-old female with lung agenesis who presented to our hospital with pneumonia and pelvic mass. In the past, she h...
journal_title:Journal of thoracic disease
pub_type:
doi:10.3978/j.issn.2072-1439.2016.01.23
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:Spontaneous pneumothoraces (SP) tend to occur in clusters which have been related to atmospheric pressure variations and thunderstorm insurgence. We examined the influence of standard meteorological parameter variations and concentrations of the major air pollutants on incidence of spontaneous pneumothorax (...
journal_title:Journal of thoracic disease
pub_type: 杂志文章
doi:
更新日期:2010-03-01 00:00:00
abstract::Approximately 6% of women with breast cancer are diagnosed before the age of 40. Young age is an independent predictor of adverse outcome and most young breast cancer patients receive systemic treatment with chemotherapy, hormonal therapy or both. The loss or impairment of fertility is a potential side effect of antin...
journal_title:Journal of thoracic disease
pub_type: 杂志文章
doi:10.3978/j.issn.2072-1439.2013.05.22
更新日期:2013-06-01 00:00:00
abstract:BACKGROUND:To evaluate the feasibility of a combined strategy including conventional-trans-bronchial needle aspiration biopsy (C-TBNA) and endobronchial ultrasounds transbronchial needle aspiration (EBUS-TBNA) for sampling mediastinal adenopathies in patients with lung cancer in order to determinate whether in the era ...
journal_title:Journal of thoracic disease
pub_type: 杂志文章
doi:10.21037/jtd.2017.04.13
更新日期:2017-05-01 00:00:00
abstract:Background:Obstructive sleep apnea (OSA) is an independent risk factor for hypertension. OSA-related hypertension is common and treatment of OSA can reduce blood pressure (BP). However, few studies have been conducted on this type of hypertension in the Chinese occupational population. Methods:We conducted a field inv...
journal_title:Journal of thoracic disease
pub_type: 杂志文章
doi:10.21037/jtd.2019.09.83
更新日期:2019-10-01 00:00:00
abstract:Background:Calcific aortic valve disease (CAVD) is the most common type of valvular heart disease in the elderly. This study is aimed to explore molecular mechanism of CAVD via bioinformatics analysis. Methods:The gene expression profiles of GSE51472 (including 5 normal aortic valve and 5 calcified aortic valve) and G...
journal_title:Journal of thoracic disease
pub_type: 杂志文章
doi:10.21037/jtd.2019.11.57
更新日期:2019-12-01 00:00:00
abstract::Improving patient safety seems to be a new interesting clinical subject but, in fact, it is no new. It has to do with one of the oldest ethical principles of our profession: curing and not harming. The important research that has been done in a short period of time has brought in new insight to this complex area that ...
journal_title:Journal of thoracic disease
pub_type: 杂志文章,评审
doi:10.3978/j.issn.2072-1439.2015.03.13
更新日期:2015-04-01 00:00:00
abstract:BACKGROUND:Lung is a common organ of metastases in patients with primary breast cancer. Pulmonary metastasis of primary breast cancer is usually considered as a systemic disease, however, the systemic approaches have achieved little progress in terms of prolonging survival time. In contrast, some studies revealed a pro...
journal_title:Journal of thoracic disease
pub_type: 杂志文章
doi:10.3978/j.issn.2072-1439.2015.08.10
更新日期:2015-08-01 00:00:00
abstract::This video demonstrated a performance of uniportal video-assisted thoracoscopic surgery (VATS) right upper lobectomy with systemic lymphadenectomy. The patient had a malignant mass in his right upper lobe. The operator took a posterior to anterior approach to dissection the right upper lobe, the adjacent structures we...
journal_title:Journal of thoracic disease
pub_type: 杂志文章
doi:10.21037/jtd.2016.05.01
更新日期:2016-08-01 00:00:00
abstract:Background:The purpose of this study is to develop a radiomics approach to predict brain metastasis (BM) for stage III/IV ALK-positive non-small cell lung cancer (NSCLC) patients. Methods:Patients with ALK-positive III/IV NSCLC from 2014 to 2017 were enrolled retrospectively. Their pretreatment thoracic CT images were...
journal_title:Journal of thoracic disease
pub_type: 杂志文章
doi:10.21037/jtd.2019.11.01
更新日期:2019-11-01 00:00:00
abstract:Background:Post-polio syndrome is characterised by symptoms of fatigue, pain and new-onset neuromuscular weakness, and emerges decades after the initial poliovirus infection. We sought to evaluate the only post-polio syndrome specific self-management programme in the United Kingdom. Methods:This was a retrospective st...
journal_title:Journal of thoracic disease
pub_type: 杂志文章
doi:10.21037/jtd-cus-2020-009
更新日期:2020-10-01 00:00:00
abstract:OBJECTIVE:To report a rare case of atypical histiocytic tumor of the lung with a review of literature. METHODS:The clinical materials were noted. Literature related to this condition from the past 50 years was reviewed from the group of histiocytic tumors. RESULTS AND CONCLUSIONS:Clinical manifestations were non-spec...
journal_title:Journal of thoracic disease
pub_type:
doi:10.3978/j.issn.2072-1439.2013.07.26
更新日期:2013-08-01 00:00:00
abstract::Transcatheter aortic valve implantation (TAVI) has gained widespread acceptance as a treatment option for patients at high risk for conventional aortic valve replacement. The most commonly used access site for TAVI is the common femoral artery. Yet, in a significant number of patients the transfemoral access is not su...
journal_title:Journal of thoracic disease
pub_type: 杂志文章,评审
doi:10.3978/j.issn.2072-1439.2015.07.27
更新日期:2015-09-01 00:00:00
abstract::In this study, we report the case of a 42-year-old female patient who was diagnosed with hemangioma in the pericardium connected to the main pulmonary artery. Chest CT revealed a hypodense, well-marginated, mass-like lesion, probably connected to the main pulmonary artery, and multiple heterogeneous attenuations were ...
journal_title:Journal of thoracic disease
pub_type:
doi:10.21037/jtd.2017.08.129
更新日期:2017-10-01 00:00:00
abstract::Obstructive sleep apnea (OSA) is a disorder which afflicts a large number of individuals around the world. OSA causes sleepiness and is a major cardiovascular risk factor. Since its inception in the early 1980's, continuous positive airway pressure (CPAP) has emerged as the major treatment of OSA, and it has been show...
journal_title:Journal of thoracic disease
pub_type: 杂志文章,评审
doi:10.3978/j.issn.2072-1439.2015.07.30
更新日期:2015-08-01 00:00:00
abstract::Aortic stenosis is the most common valvular disease worldwide. With transcatheter aortic valve replacement (TAVR) being increasingly expanded to lower-risk populations, several challenging issues remain to be solved. The present review aims at discussing modern approaches to such issues as well as the current status o...
journal_title:Journal of thoracic disease
pub_type: 杂志文章,评审
doi:10.21037/jtd.2020.01.10
更新日期:2020-04-01 00:00:00
abstract::The medical management of bronchiectasis includes confirming the diagnosis of the disease, evaluating the patient for possible underlying etiologies and then properly assessing the patient for appropriate therapies. Patients with bronchiectasis are heterogeneous and a personalized approach to each patient is needed in...
journal_title:Journal of thoracic disease
pub_type: 杂志文章,评审
doi:10.21037/jtd.2018.09.39
更新日期:2018-10-01 00:00:00
abstract::Presented is a rare case of a primary melanoma of the lung in an 89 year old male patient. Primary melanoma of the lung has been previously reported in the English literature in about 30 patients. Surgical resection either with lobectomy of pneumonectomy and a lymph node dissection has been shown to be the best chance...
journal_title:Journal of thoracic disease
pub_type:
doi:10.3978/j.issn.2072-1439.2011.04.02
更新日期:2011-09-01 00:00:00
abstract:BACKGROUND:A challenge for resection of thoracic inlet tumors lies in that high risk of injuring vital blood vessels and brachial plexus still exists during the resection. And the standard surgical approach for resection of thoracic inlet tumors has not yet been well established. METHODS:Small cervical incision-assist...
journal_title:Journal of thoracic disease
pub_type: 杂志文章
doi:10.21037/jtd.2016.10.52
更新日期:2016-10-01 00:00:00
abstract::Response monitoring using fluorodeoxyglucose positron emission tomography acquired together with low dose computed tomography (FDG-PET/CT) textural features has potential in targeted treatment with erlotinib in non-small cell lung cancer (NSCLC) patients. Patients with substantial decrease of metabolic activity during...
journal_title:Journal of thoracic disease
pub_type: 杂志文章
doi:10.21037/jtd.2016.02.10
更新日期:2016-03-01 00:00:00
abstract::The development of advanced radiation technologies, including intensity-modulated radiation therapy (IMRT), stereotactic body radiation therapy (SBRT) and proton therapy, has resulted in increasingly conformal radiation treatments. Recent evidence for the importance of minimizing dose to normal critical structures inc...
journal_title:Journal of thoracic disease
pub_type: 杂志文章,评审
doi:10.21037/jtd.2018.01.155
更新日期:2018-08-01 00:00:00
abstract:Background:To investigate the capability of radiomic analysis using T2-weighted (T2W) and spectral attenuated inversion-recovery T2-weighted (SPAIR T2W) magnetic resonance imaging (MRI) for predicting the therapeutic response of esophageal squamous cell carcinoma (ESCC) to chemoradiotherapy (CRT). Methods:Pretreatment...
journal_title:Journal of thoracic disease
pub_type: 杂志文章
doi:10.21037/jtd.2018.03.123
更新日期:2018-04-01 00:00:00
abstract:Background:Optimal preservation of endothelial integrity of the vessels used as aortocoronary grafts is a crucial determinant of long-term clinical success of coronary artery bypass grafting (CABG). The purpose of this study was to evaluate an impact of two common techniques to harvest left internal thoracic artery (LI...
journal_title:Journal of thoracic disease
pub_type: 杂志文章
doi:10.21037/jtd.2018.07.62
更新日期:2018-08-01 00:00:00
abstract:Background:Chronic obstructive pulmonary disease (COPD) is one of the leading causes of mortality and morbidity around the world, with comorbidities in COPD being common and having a negative effect on survival. We investigate the effects of comorbidities on long-term survival of COPD patients. Methods:The study inclu...
journal_title:Journal of thoracic disease
pub_type: 杂志文章
doi:10.21037/jtd.2019.03.78
更新日期:2019-04-01 00:00:00
abstract::Management of pulmonary nodules in terms of diagnosis and intraoperative localization can be challenging, especially in the minimal invasive video-assisted thoracoscopic surgery (VATS) approach, and may be even more difficult with single port VATS with limited access. The ability to localize small lesions intraoperati...
journal_title:Journal of thoracic disease
pub_type: 杂志文章,评审
doi:10.3978/j.issn.2072-1439.2016.02.27
更新日期:2016-03-01 00:00:00