Pathological complete response to neoadjuvant trastuzumab and pertuzumab therapy is related to human epidermal growth factor receptor 2 (HER2) amplification level in HER2-amplified breast cancer.

abstract：RATIONALE:The precise cause of granulomatosis with polyangiitis (GPA) remains unclear. Herein we present a case of refractory GPA occurring after trauma. PATIENT CONCERNS:A 43-year-old man suffered fractures of the left orbital in an accident, and then received surgical repair. At a postoperative follow-up, he develop...

journal_title：Medicine

authors： Deng S,Xing Y,Wang H,Kong X

更新日期：2019-01-01 00:00:00

abstract：:Complications after cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) result in impaired short- and long-term outcomes. However, financial consequences of complications after CRS and HIPEC in a European health care setting are unknown. This study aims to assess the consequences of compl...

journal_title：Medicine

authors： Simkens GA,Rovers KP,van Oudheusden TR,Nienhuijs SW,Rutten HJ,de Hingh IH

更新日期：2018-03-01 00:00:00

abstract：:The study aim is to compare anal intraepithelial neoplasia (AIN) progression and regression rates in a cytology inception cohort to estimates based on the subcohort referred for ≥1 high-resolution anoscopies (HRAs).A cytology-based retrospective cohort was assembled including the anal cytology histories and invasive a...

journal_title：Medicine

authors： Mathews WC,Cachay ER,Agmas W,Jackson C

更新日期：2015-09-01 00:00:00

abstract：:Traditionally, tension band fixation has been used for treating simple fracture patterns; however, fixation remains a challenge, especially for comminuted fractures. We describe a new method of operation using a combination of a miniature plate with tension band wiring to treat comminuted patellar fractures. The aim o...

journal_title：Medicine

authors： Gao S,Zhang F,Gao T,Liu X,Zhang Z,Dai M

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Plate fixation and intramedullary nail/Knowles pin fixation methods are commonly used to treat displaced midshaft clavicle fractures. However, the differences between these 2 methods are unclear. OBJECTIVE:This meta-analysis aimed to compare plate fixation and intramedullary nail/Knowles pin fixation for di...

journal_title：Medicine

authors： Li L,Yang X,Xing F,Jiang J,Tang X

更新日期：2020-09-25 00:00:00

abstract：RATIONALE:Primary hepatic lymphoma (PHL) is an extremely rare manifestation of extranodal non-Hodgkin lymphoma. There were few cases about PHL in recent years, while cases using positron emission tomography (PET) modalities for both diagnosis and follow-up were even rare. PATIENT CONCERNS:A 29-year-old man complaining...

journal_title：Medicine

authors： Wang L,Dong P,Hu W,Tian B

更新日期：2020-01-01 00:00:00

abstract：:Venous thromboembolism (VTE) is a common vascular disorder with high mortality and morbidity. Clinical nurses are a pivotal group that can serve as first-line health care providers. Lack of knowledge about VTE is an important barrier to effective nursing performance. This study aimed to determine nurses' knowledge of ...

journal_title：Medicine

authors： Ma YF,Xu Y,Chen YP,Wang XJ,Deng HB,He Y,Wu XJ

更新日期：2018-04-01 00:00:00

abstract：RATIONALE:Pulmonary embolism can manifest by a myriad of clinical symptoms. High grade fever is a rare presentation of thromboembolic phenomenon. PATIENT CONCERNS:A middle aged woman presented with high grade fevers. DIAGNOSES:Patient remained febrile despite broad spectrum antibiotics. All cultures were negative. CT...

journal_title：Medicine

authors： Saad M,Shaikh DH,Adrish M

更新日期：2018-03-01 00:00:00

abstract：BACKGROUD:The aim of the study was to evaluate the effect of early parenteral iron supplementation combined erythropoietin for prevention of anemia in preterm infants. METHODS:In total, 96 preterm infants were randomly assigned to 3 groups: a control group receiving standard parenteral nutrition (group 1: n = 31), an ...

journal_title：Medicine

authors： Qiao L,Tang Q,Zhu W,Zhang H,Zhu Y,Wang H

更新日期：2017-03-01 00:00:00

abstract：:Prosthetic Valve Thrombosis (PVT), in spite of the advances in the valve design and the material used, remains a serious complication of mechanical cardiac valve replacement. The factors influencing the development of PVT are: thrombogenicity of the valve, hemodynamics of the transprosthetic blood flow and ineffective...

journal_title：Medicine

authors： Sr K,G B,Jain S,Moorthy N,Manjunath SC,Christopher R

更新日期：2019-02-01 00:00:00

abstract：:The aim of the study was to investigate diagnosis efficacy of dynamic contrast-enhanced MRI (DCE-MRI) and diffusion-weighted MRI (DW-MRI) in Crohn's disease (CD). To find out the correlations between functional MRI parameters including K, Kep, Ve, Vp, and apparent diffusion coefficient (ADC) with a serologic biomarker...

journal_title：Medicine

authors： Zhu J,Zhang F,Luan Y,Cao P,Liu F,He W,Wang D

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:With advancements in our understanding of meniscal function, treatment options for meniscal injuries have evolved considerably over the past few decades. The aim of the current study was to compare the all-inside and inside-out techniques with regard to retear rate, functional outcomes, and perioperative com...

journal_title：Medicine

authors： Lin Y,Zhao J,Qiu H,Huang Y

更新日期：2020-07-02 00:00:00

abstract：:A wide array of drugs are available for the treatment of lower urinary tract symptoms associated with benign prostatic hyperplasia (BPH), but the evidence for the comparative effectiveness is controversial.The objective of this study is to evaluate the comparative effectiveness and safety of monodrug therapies for BPH...

journal_title：Medicine

authors： Yuan JQ,Mao C,Wong SY,Yang ZY,Fu XH,Dai XY,Tang JL

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:To explore the features and function of gut microbiota in necrotizing enterocolitis patients over 28 gestational age weeks through a case-control study. METHODS:Fecal samples from patients with NEC over 28 gestational week age and matched control cases were collected. DNA of the fecal samples was extracted ...

journal_title：Medicine

authors： Feng J,He Y,Liu D,Li L,Chen J,Yu J

更新日期：2019-10-01 00:00:00

abstract：:For proximal varus osteotomy of the femur in children, a stable fixation, is a concern regarding the safety and the protection of the surgery. The methods of fixation are mostly represented by plating systems; however, the tension band wiring is a simple and eligible option for fixation of proximal femur osteotomy. Th...

journal_title：Medicine

authors： Maranho DA,Pagnano RG,Volpon JB

更新日期：2014-08-01 00:00:00

abstract：:In the current era of multidrug-resistant organisms, the clinical spectrum of Streptococcus pneumoniae infection remains unclear, especially in immunosuppressed patients with cancer. We sought to define the characteristics of pneumococcal bacteremia in patients who were receiving care at a comprehensive cancer center....

journal_title：Medicine

authors： Kumashi P,Girgawy E,Tarrand JJ,Rolston KV,Raad II,Safdar A

更新日期：2005-09-01 00:00:00

abstract：:CD34 is a transmembrane phosphoglycoprotein that was first identified on hematopoietic stem and progenitor cells. CD34 is known as an optimum marker for microvascular density studies and it is positively stained in pathological and physiologic vessels. The use of CD34 for the prognosis, diagnosis, and treatment of neo...

journal_title：Medicine

authors： Kong X,Guan J,Ma W,Li Y,Xing B,Yang Y,Wang Y,Gao J,Wei J,Yao Y,Xu Z,Dou W,Lian W,Su C,Ren Z,Wang R

更新日期：2016-02-01 00:00:00

abstract：:Current state-of-the-art nuclear medicine imaging methods (such as PET/CT or bone scintigraphy) may have insufficient sensitivity for predicting bone tumor, and substantial exposure to ionizing radiation is associated with the risk of secondary cancer development. Diffusion-weighted MRI (DW-MRI) is radiation free and ...

journal_title：Medicine

authors： Liu LP,Cui LB,Zhang XX,Cao J,Chang N,Tang X,Qi S,Zhang XL,Yin H,Zhang J

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:To compare superb microvascular imaging with power Doppler imaging for evaluating joint lesion scores in rheumatoid arthritis based on high quality clinical cohort or case control studies. METHODS:We searched Medline (via PubMed), Web of Science, Cochrane Library, Embase, and Chinese Biomedical Literature D...

journal_title：Medicine

authors： Lin M,Wang C

更新日期：2020-09-11 00:00:00

abstract：:Patients with classical heat stroke are different in many ways from those with exertional injury; contrasts included difference in demographic factors, prior general health, in-hospital complications and laboratory abnormalities (lactate, liver enzymes, pH, electrolytes). Severe hyperkalemia, acute renal failure, rhab...

journal_title：Medicine

authors： Hart GR,Anderson RJ,Crumpler CP,Shulkin A,Reed G,Knochel JP

更新日期：1982-05-01 00:00:00

abstract：INTRODUCTION:Eosinophilic esophagitis (EoE) is a chronic, immune/antigen-mediated disease characterized clinically by symptoms related to esophageal dysfunction and histologically by a marked eosinophilic infiltrate in the esophageal mucosa. What was once considered a rare disease has nowadays become one of the most fr...

journal_title：Medicine

authors： Trifan A,Stoica O,Chihaia CA,Danciu M,Stanciu C,Singeap AM

更新日期：2016-10-01 00:00:00

abstract：:The neutrophil-to-lymphocyte ratio (NLR) and the platelet-to-lymphocyte ratio (PLR) are not fully evaluated for the diagnosis of musculoskeletal tumors, especially spine tumors. The objective of our study was to assess the feasibility of NLR and PLR as indicators for pretreatment diagnosis of spine tumors.Patients who...

journal_title：Medicine

authors： Li Y,Wang B,Zhou S,Jiang L,Yang S,Liu X,Wei F,Zhang H,Wang Y,Liu Z

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Perimenopausal insomnia (PI) is one of the most common complaints in women. Acupuncture is used to treat PI increasingly considering its less side effect. The subject of this study is to explore the effectiveness and safety of acupuncture for PI. METHODS:All the randomized controlled trials(RCT) literatures...

journal_title：Medicine

authors： Guo T,Jia M,Jin Y,Xu N,Peng T

更新日期：2018-06-01 00:00:00

abstract：:We aimed to show the utility and reliability of sternal morphometric analysis for sex estimation.Sex estimation is a very important step in forensic identification. Skeletal surveys are main methods for sex estimation studies. Morphometric analysis of sternum may provide high accuracy rated data in sex discrimination....

journal_title：Medicine

authors： Ekizoglu O,Hocaoglu E,Inci E,Bilgili MG,Solmaz D,Erdil I,Can IO

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:To evaluate the analgesic efficacy on defined areas of the abdomen and back after ultrasound-guided subcostal transversus abdominis plane (TAP) block using 0.25% levobupivacaine 0.5 mL/kg. METHODS:Twenty patients undergoing elective laparoscopic cholecystectomy, between 20 and 60 years of age with operative...

journal_title：Medicine

authors： Ma J,Jiang Y,Tang S,Wang B,Lian Q,Xie Z,Li J

更新日期：2017-03-01 00:00:00

abstract：:Preoperational hemogram parameters have been reported to be associated with the prognosis of several types of cancers. This study aimed to investigate the prognostic value of hematological parameters in gastric cancer in a Chinese population. A total of 870 gastric cancer patients who underwent radical tumorectomy wer...

journal_title：Medicine

authors： Pan YC,Jia ZF,Cao DH,Wu YH,Jiang J,Wen SM,Zhao D,Zhang SL,Cao XY

更新日期：2018-12-01 00:00:00

abstract：RATIONALE:The stomach is always used to reconstruct the upper digestive tract for esophageal cancer operation. However, problems arise when the esophageal cancer and gastric cancer present at the same time. No medical literature mentioned about this surgical procedure till now. PATIENT CONCERNS:Majority of the patient...

journal_title：Medicine

authors： Zhao Y,Cong B

更新日期：2019-03-01 00:00:00

abstract：:To explore the relationship between risk prediction of diabetes mellitus (DM) and different physical fitness parameters in municipal in-service personnel in Guangxi.This was a cross-sectional study conducted in China from July 2015 to December 2016. We enrolled in-service adults (20-65 year of age) from public institu...

journal_title：Medicine

authors： Zhao M,Wu Z,Huang Y,Jiang Z,Mo X,Lowis H,Zhao Y,Zhang M

更新日期：2019-05-01 00:00:00

abstract：RATIONALE:Ramsay Hunt syndrome in conjunction with cranial polyneuritis is not extensively documented, and is very easily misdiagnosed. PATIENT CONCERNS:A case of a 53-year-old male with Ramsay Hunt syndrome in conjunction with cranial polyneuritis is presented with early symptoms of vertigo, cephalalgia, and facial p...

journal_title：Medicine

authors： Zheng RW,Liu D,Eric TE,Ning YZ,Chen LL,Hu H,Ren Y

更新日期：2017-11-01 00:00:00

abstract：:Hyperglycemia is common during and after Coronary Artery Bypass Graft Surgery (CABGS) and has been shown to be associated with poor clinical outcomes. In this study, we hypothesized that a moderate perioperative mean blood glucose level of <150 mg/dL improves long-term survival in cardiac surgery patients. We conducte...

journal_title：Medicine

authors： Mansur A,Popov AF,Hanna AA,Bergmann I,Brandes IF,Beissbarth T,Bauer M,Hinz J

更新日期：2015-11-01 00:00:00