Abstract:
INTRODUCTION:Trigeminal neuralgia (TN) secondary to tumors is encountered in up to 6% of patients with facial pain syndromes and is considered to be associated with tumors affecting the trigeminal nerve pathways. The most frequent are meningiomas and vestibular schwannomas (VS). Stereotactic radiosurgery (SRS) has emerged as a valuable treatment, with heterogeneity of clinical results. We sought to review the medical literature on TN treated with SRS for meningiomas and VS and investigate the rates of improvement of TN symptoms. METHODS:We reviewed articles published between January 1990 and December 2019 in PubMed. Pain relief after SRS, the maintenance of pain relief, and TN recurrence and complications were evaluated with separate meta-analyses, taking into account the data on individual patients. RESULTS:Pain relief after SRS was reported as Barrow Neurological Institute (BNI) pain intensity scores of BNI I in 50.5% (range 36-65.1%) of patients and BNI I-IIIb in 83.8% (range 77.8-89.8%). There was no significant difference in series discussing outcomes for tumor targeting versus tumor and nerve targeting. Recurrences were described in 34.7% (range 21.7-47.6; tumor targeting). Maintenance of BNI I was reported in 36.4% (range 20.1-52.7) and BNI I-IIIb in 41.2% (range 29.8-52.7; tumor targeting series). When both the nerve and the tumor were targeted, only 1 series reported 86.7% with BNI I-IIIb at last follow-up. Complications were encountered in 12.6% (range 6.3-18.8; tumor targeting series) of patients; however, they were much higher, as high as 26.7%, in the only study reporting them after targeting both the nerve and the tumor. The most common complication was facial numbness. CONCLUSION:SRS for TNB secondary to benign tumors, such as meningiomas and VS, is associated with favorable clinical course, but less favorable than in idiopathic TN. There was, however, heterogeneity among reports and targeting approaches. Although targeting both the nerve and the tumor seemed to achieve better long-term results, the rate of complications was much higher and the number of patients treated was limited. Future clinical studies should focus on the standard reporting of clinical outcomes and randomization of targeting methods.
journal_name
Stereotact Funct Neurosurgjournal_title
Stereotactic and functional neurosurgeryauthors
Peciu-Florianu I,Régis J,Levivier M,Dedeciusova M,Reyns N,Tuleasca Cdoi
10.1159/000509842subject
Has Abstractpub_date
2020-09-09 00:00:00pages
1-11eissn
1011-6125issn
1423-0372pii
000509842pub_type
杂志文章,评审abstract:BACKGROUND/AIMS:Technological advancements had a serious impact on the evolution of robotic systems in stereotactic neurosurgery over the last three decades and may turn robot-assisted stereotactic neurosurgery into a sophisticated alternative to purely mechanical guiding devices. OBJECTIVES:To compare robot-assisted ...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000494736
更新日期:2018-01-01 00:00:00
abstract::In many cases, the treatment of neuropathic pain by intrathecal opioids fails to meet expectations. In a trial involving 10 patients, the intrathecal administration of clonidine combined with opioids in the treatment of chronic pain was introduced in our department for the first time. Eight patients with neuropathic p...
journal_title:Stereotactic and functional neurosurgery
pub_type: 临床试验,杂志文章
doi:10.1159/000048402
更新日期:2000-01-01 00:00:00
abstract::Functional neurosurgery usually requires physiological corroboration of the target site, particularly by eliciting characteristic responses to stimulation, or else by microelectrode recording of single cell responses to appropriate stimuli. Understanding pain physiology with both strategies has proven elusive, particu...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000064605
更新日期:2001-01-01 00:00:00
abstract::Dorsal root entry zone (DREZ) lesioning is still used as a choice of treatment for some painful conditions as well as spasticity in selected patients. The most commonly used techniques to perform DREZotomy are the microsurgical one and DREZ radiofrequency (RF) coagulation. The technical difficulties using punctures to...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000500491
更新日期:2019-01-01 00:00:00
abstract::We reviewed the initial experience with 331 consecutive patients treated during the first 2 years of operation of the University of Pittsburgh Gamma Unit. Among 178 patients with vascular malformations, 161 had angiographically demonstrable arteriovenous malformations, and 17 had angiographically occult malformations....
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000100269
更新日期:1990-01-01 00:00:00
abstract:INTRODUCTION:The primary goal of stereotactic systems in deep brain stimulation (DBS) surgery is accurate delivery of a DBS lead to a target identified on imaging. Thus, it is critical to understand the accuracy of the stereotactic systems and the factors which may be associated with a decrease in accuracy. METHODS:Ni...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000316761
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND/AIMS:Postoperative cerebral edema around a deep brain stimulation (DBS) electrode is an uncommon reported complication. The goal of this study was to identify instances of postoperative edema based on clinical presentation, and to remark on their management. METHODS:A retrospective chart review was performe...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000454892
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND/AIMS:Stereotactic postoperative imaging is essential for verification of the position of electrodes implanted for deep brain stimulation (DBS). MRI offers superior visualisation of the DBS targets relative to CT, but previous adverse incidents have heightened concerns about risks of postoperative MRI. Preope...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000225973
更新日期:2009-01-01 00:00:00
abstract::Today's image guidance systems are the foundation of minimally invasive diagnosis and therapy and are the basis for the rational design of the neurosurgical operating room of the future. The building blocks of this procedural arena will be (1) high-resolution MR/CT anatomic imaging supplemented with (2) functional ima...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章,评审
doi:10.1159/000029773
更新日期:1999-01-01 00:00:00
abstract::Out of 57 patients operated for intractable epilepsy of the central region, 8 harbored an indolent glioma (7 dysembryoplastic neuroepithelial tumors, 1 ganglioglioma). Mapping of the sensorimotor area with depth electrodes implanted for stereoelectroencephalographic exploration demonstrated no or abnormal motor respon...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000099880
更新日期:1997-01-01 00:00:00
abstract::We have analyzed a series of 225 patients with intracranial metastases (343 lesions), treated in our department by Gamma Knife radiosurgery over a 30-month period. We have used a modified Pittsburgh protocol and performed 242 procedures on 164 single/78 multiple lesions. Primary tumors were mostly carcinomas of the lu...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000099809
更新日期:1996-01-01 00:00:00
abstract::Autologous transplantation of the superior cervical ganglion (SCG) into the caudate nuclei of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonian monkey was studied in regard to animal behavior and catecholamine (CA) metabolites in cerebrospinal fluid. Monkeys which had undergone autotransplantation of t...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000100231
更新日期:1990-01-01 00:00:00
abstract:PURPOSE:To evaluate the imaging and pathological correlates of successful or risk-related stereotactic radiosurgery (SR). Methods and Materials. The ten-year Gamma Knife experience in 2,344 patients at the University of Pittsburgh was reviewed. In addition, the results or radiosurgery primate, rat, and mouse models wer...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000056401
更新日期:1998-10-01 00:00:00
abstract::Ablation of the globus pallidus internus (GPi) and thalamotomy have been extensively used in the past. Posteroventral GPi deep brain stimulation has been considered as a treatment for dystonia. However, to date, there is no report in the literature of any dystonia patient who underwent GPi deep brain stimulation who h...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000325660
更新日期:2011-01-01 00:00:00
abstract::Ki67 (also known as MIB) is a monoclonal antibody staining agent, which is routinely used as a marker of cellular proliferation. It is used to evaluate the proliferative potential of malignant tumors, since it is thought to stain only those cells undergoing active division. The paradoxical elevation of the Ki67 labeli...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000056438
更新日期:1999-01-01 00:00:00
abstract::Experimental studies indicate that deafferentation results in reorganization of the somatosensory map at various levels of the CNS, such that the representation of a body part adjacent to a region that is denervated expands into the deafferented area. Recent data suggest that in the human this occurs at the cortical l...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000098612
更新日期:1994-01-01 00:00:00
abstract::Since its introduction to neurosurgery in 2008, laser ablative techniques have been largely confined to the management of unresectable tumors. Application of this technology for the management of focal epilepsy in the adult population has not been fully explored. Given that nearly 1,000,000 Americans live with medical...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000366001
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Deep brain stimulation (DBS) and the proper target for chronic cluster headache (CCH) are still subjects of controversy. OBJECTIVES:We present our long-term results of analysis of the target and its structural connectivity. METHODS:Fifteen patients with drug-resistant CCH underwent DBS in coordinates 4 mm ...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000489937
更新日期:2018-01-01 00:00:00
abstract::Clinical experience with the use of pergolide is presented in 55 patients with Parkinson's disease. Fifty to 900 micrograms/day (mean 242.73, SD 217.51) of pergolide and 0.64-17.05 micrograms/kg/day (mean 4.58, SD 4.25) pergolide was given together with L-carbidopa to 29 males and 26 females for a period of up to 2 ye...
journal_title:Stereotactic and functional neurosurgery
pub_type: 临床试验,杂志文章
doi:10.1159/000099849
更新日期:1997-01-01 00:00:00
abstract::In his keynote address, the author reviews early work in the surgical management of the epilepsies and presents a state-of-the-art review of current basic science and clinical indications for and results from corpus callosotomy for the treatment of seizure disorders. ...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章,评审
doi:10.1159/000098621
更新日期:1994-01-01 00:00:00
abstract::Somatosensory evoked potentials (SEP) were monitored intraoperatively in 15 patients who underwent spinal cord radiofrequency thermal dorsal root entry zone (DREZ) lesion procedures to treat chronic deafferentation pain. We found a significant correlation between transient latency shifts (recovery to prelesion values ...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000099539
更新日期:1989-01-01 00:00:00
abstract::The objective of this case report is to demonstrate that a benign tumour arising solely from the olfactory bulb can act as a primary epileptic focus and to illustrate the difficulty in making a preoperative diagnosis of pathological lesions in this area. The case of a 29-year-old male with intractable epilepsy is pres...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000070104
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND/AIMS:Parkinson's disease (PD) is an idiopathic progressive neurological disorder. Improvement in motor function of PD patients has been established with subthalamic nucleus (STN) deep brain stimulation (DBS). While variations in DBS settings (i.e. amplitude, frequency and pulse width) on motor function have ...
journal_title:Stereotactic and functional neurosurgery
pub_type: 临床试验,杂志文章
doi:10.1159/000163554
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:To date, no consensus has been reached regarding validated and practical tools to quantify the severity of hemifacial spasm (HFS) before and after surgery. OBJECTIVE:The aim of this study has been to establish objective parameters for determining the preoperative severity of HFS and to assess the correlatio...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000330396
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:Brain metastasis (BM) is the most common brain malignancy and a common cause of death in cancer patients. However, the relative outcome-related advantages and disadvantages of surgical resection (SR) and stereotactic radiosurgery (SRS) in the initial treatment of BM are controversial. METHOD:We systematical...
journal_title:Stereotactic and functional neurosurgery
pub_type: meta分析
doi:10.1159/000509319
更新日期:2020-01-01 00:00:00
abstract::We report a case of induced oscillopsia caused by deep brain stimulation (DBS) of the pedunculopontine nucleus (PPN). Recent reports have described involuntary oscillopsia during DBS of the PPN that patients have described as trembling vision. Here we substantiate this observation using infra-red eye tracking. It has ...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000335871
更新日期:2012-01-01 00:00:00
abstract::Spinal cord stimulation (SCS) has been reported to be effective treatment for the failed back surgery syndrome in a number of retrospective case series. Its retrospectively reported results compare favorably with those of neurosurgical treatment alternatives, such as reoperation and ablative procedures. There has been...
journal_title:Stereotactic and functional neurosurgery
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000098631
更新日期:1994-01-01 00:00:00
abstract::Image-directed neurosurgical systems allow the correlation of a point in the operative field to a corresponding point on the patient's CT/MR scans. We have modified a surgical microscope by mounting three light-emitting diodes (LEDs) on a small frame attached to the microscope. The operative field was registered to th...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000099675
更新日期:1996-01-01 00:00:00
abstract:BACKGROUND:Few multiple case studies of the effects of deep brain stimulation for camptocormia associated with Parkinson's disease have been reported. Although deep brain stimulation was in some cases not effective against camptocormia, it is unclear in which types of patients it was effective in treating camptocormia....
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000324907
更新日期:2011-01-01 00:00:00
abstract::A simple technique has been designed which identifies the gantry isocenter and aligns the laser beams to the isocenter of the gantry within 3-5 min with an error of less than 0.75 mm, depending upon the accuracy of gantry rotation. ...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000099516
更新日期:1989-01-01 00:00:00