Shunting outcomes in post-hemorrhagic hydrocephalus: A protocol for systematic review and meta-analysis.

Abstract:

BACKGROUND:The best treatment option for patients with post-hemorrhagic hydrocephalus (PHH) remains controversial. The objective of the current meta-analysis is to systematically evaluate the long-term outcomes of patients with PHH treated by ventriculoperitoneal shunt (VPS) and lumboperitoneal shunt (LPS). METHODS:We search literatures through PubMed, Web of Science, Embase, Cochrane Library, China National Knowledge Infrastructure (CNKI), the Chinese Science and Technology Periodical Database (VIP) and Wan fang databases, and Chinese Biomedical Literature Database (CBM) from its beginning to June 15, 2020. Randomized controlled trials (RCTs) and non-RCTs in English or Chinese studies will be considered. The primary outcome is the rate of shunt failure after shunt implantationThe secondary outcome is the rate of complications that are associated with shunt surgery. RESULTS AND CONCLUSION:The study will compare the 2 types of shunt surgery in the treatment of PHH, providing evidence for the treatment option for the patients with PHH. STUDY REGISTRATION NUMBER:The study is priorly registered through International Platform of Registered Systematic Review and Meta-analysis Protocols on June 17, 2020 (INPLASY202060063).

journal_name

Medicine (Baltimore)

journal_title

Medicine

authors

Sun T,Guan J,You C,Yang J,Li X,Yuan Y,Zhou Y

doi

10.1097/MD.0000000000021640

subject

Has Abstract

pub_date

2020-08-07 00:00:00

pages

e21640

issue

32

eissn

0025-7974

issn

1536-5964

pii

00005792-202008070-00071

journal_volume

99

pub_type

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