Abstract:
INTRODUCTION:Post-traumatic stress disorder (PTSD) is a severe and debilitating condition affecting a significant proportion of the veteran community. A substantial number of veterans with PTSD fail to benefit from trauma-focused psychological therapies or pharmacotherapy or are left with residual symptoms, and therefore, investigation of new and innovative treatment is required. Theta Burst Stimulation (TBS) is a novel form of Repetitive Transcranial Magnetic Stimulation, which has been shown to improve depression symptoms and associated cognitive deficits. The current pilot study aimed to explore the acceptability, safety, and tolerability of intermittent TBS (iTBS) as a treatment for PTSD in Australian veterans. MATERIALS AND METHODS:This study employed a case series, repeated-measures design. Eight Australian Defence Force veterans with PTSD received 20 bilateral iTBS treatments (1 session per day, 5 days per week over a 4-week period) and were assessed on a range of mental health and neuropsychological measures, including the Clinician-Administered PTSD Scale for DSM-5 (CAPS-5) and Hamilton Depression Rating Scale (HAM-D), at pretreatment, post-treatment, and a 3-month follow-up. RESULTS:Treatment was generally welltolerated, with reported side-effects including mild to moderate site-specific cranial pain and headaches during stimulation, which were relieved with the use of low dose analgesics. No serious side effects or adverse events were reported. Participants exhibited reductions in both PTSD and depression symptom severity (the repeated-measures effect size [dRM] for the CAPS-5 was -1.78, and the HAM-D was -1.16 post-treatment), as well as improvements in working memory and processing speed. Although significance cannot be inferred, these preliminary estimates of effect size indicate change over time. CONCLUSIONS:Bilateral iTBS appears to be welltolerated by Australian veterans. Within this repeated-measures case series, iTBS treatment shows promise in reducing both PTSD and mood symptoms, as well as improving cognitive difficulties associated with these disorders. Large-scale randomized controlled trials of this promising treatment are warranted.
journal_name
Mil Medjournal_title
Military medicineauthors
Nursey J,Sbisa A,Knight H,Ralph N,Cowlishaw S,Forbes D,O'Donnell M,Hinton M,Cooper J,Hopwood M,McFarlane A,Herring S,Fitzgerald Pdoi
10.1093/milmed/usaa149subject
Has Abstractpub_date
2020-09-18 00:00:00pages
e1770-e1778issue
9-10eissn
0026-4075issn
1930-613Xpii
5864875journal_volume
185pub_type
杂志文章abstract:OBJECTIVE:To determine whether the presence of insulin resistance in obese subjects would adversely affect the rate of ovulation induction by clomiphene citrate. RESULTS:Fasting hyperinsulinemia was associated with the failure to ovulate in response to clomiphene. In addition, other parameters found to correlate with ...
journal_title:Military medicine
pub_type: 杂志文章
doi:
更新日期:1996-12-01 00:00:00
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journal_title:Military medicine
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journal_title:Military medicine
pub_type: 杂志文章
doi:
更新日期:1992-06-01 00:00:00
abstract:BACKGROUND:Foot friction blisters in military personnel lessen a soldier's mobility, concentration, and critical decision-making skills. OBJECTIVE:To determine the prevalence of and factors associated with friction blisters during deployment in all military personnel who nonurgently presented to the 28th Combat Suppor...
journal_title:Military medicine
pub_type: 杂志文章
doi:10.7205/milmed-d-11-00325
更新日期:2012-02-01 00:00:00
abstract::In combat, the tactical situation can prevent rapid evacuation to definitive care, or casualty overload can tie up the surgical teams. All medical personnel and their supporting cadre should have the ability to manage wounds and burns. Controlling bleeding and airways, cleaning and debriding wounds, and dressing or sp...
journal_title:Military medicine
pub_type: 杂志文章
doi:
更新日期:1996-08-01 00:00:00
abstract::We report on two patients with head and neck injuries, who remained asymptomatic after the earthquake for 1 and 2 years, respectively. They developed late transient ischemic neurological signs and eventually presented with complete occlusion of the internal carotid artery. They made a good recovery with medical treatm...
journal_title:Military medicine
pub_type: 杂志文章
doi:10.7205/milmed.169.7.556
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journal_title:Military medicine
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doi:
更新日期:1989-08-01 00:00:00
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journal_title:Military medicine
pub_type: 杂志文章
doi:
更新日期:1996-05-01 00:00:00
abstract::Piercing in general and particularly tongue piercing is gaining popularity in the Western world. The French army and so the French air force are concerned by this phenomenon. A case report of a pilot suffering from dental pain with operational consequences due to a dental fracture during Operation Trident (Kosovo) is ...
journal_title:Military medicine
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doi:10.7205/milmed-d-10-00149
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journal_title:Military medicine
pub_type: 杂志文章
doi:10.7205/milmed.170.5.418
更新日期:2005-05-01 00:00:00
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journal_title:Military medicine
pub_type: 杂志文章
doi:
更新日期:2005-02-01 00:00:00
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journal_title:Military medicine
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
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journal_title:Military medicine
pub_type: 杂志文章
doi:
更新日期:1990-06-01 00:00:00
abstract::A survey of 600 Army and Navy physicians deployed to the Persian Gulf during Operation Desert Storm was conducted to ascertain their concerns pertaining to the ethics of combat medicine and note any similarities with common ethical concerns in the peacetime practice of medicine. Despite expressed familiarity with the ...
journal_title:Military medicine
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
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journal_title:Military medicine
pub_type: 杂志文章
doi:10.7205/milmed.169.6.475
更新日期:2004-06-01 00:00:00
abstract::The first licensed Haemophilus influenzae type B (Hib) vaccines were of a purified capsular oligosaccharide. Unfortunately, oligosaccharides are poorly immunogenic in younger children and resulted in these vaccines not routinely being used until past the period of peak incidence of Hib disease. Subsequent Hib vaccine ...
journal_title:Military medicine
pub_type: 杂志文章
doi:
更新日期:1990-10-01 00:00:00
abstract::The massive Department of Defense deployment in support of Hurricane Andrew relief cast the military medical departments in a new role. Military medical personnel were challenged to apply the traditional principles of combat medicine to a noncombat environment, within the continental United States, within an existing ...
journal_title:Military medicine
pub_type: 杂志文章
doi:
更新日期:1994-03-01 00:00:00
abstract::Meals ready to eat (MRE) have undergone many revisions of their origins in the trench ration from World War I. The MRE was implemented in 1980. Its design allows extended storage and easy, safe meal preparation. MRE sodium content varies by meal and may range from 1.6 g/meal to 2.3 g/meal. The average MRE contains 1,2...
journal_title:Military medicine
pub_type: 杂志文章
doi:10.7205/milmed-d-09-00049
更新日期:2010-03-01 00:00:00
abstract::This study explores what factors influence whether active duty U.S. military personnel enroll their families in Department of Defense (DoD) or non-DoD dental insurance plans. The data come from a 26-site, cross-sectional survey of U.S. service members conducted from April 1994 to January 1995. A prestratified, randoml...
journal_title:Military medicine
pub_type: 杂志文章
doi:
更新日期:1998-12-01 00:00:00
abstract::This article describes the postinjury cognitive functioning of a sample of active duty, retired, and military beneficiaries who received traumatic brain injuries. Patients were seen in the neuropsychology clinic at Brooke Army Medical Center for a detailed cognitive and personality assessment. The scores on a major co...
journal_title:Military medicine
pub_type: 杂志文章
doi:
更新日期:2003-12-01 00:00:00
abstract::Over the last 50 years, members of the U.S. military have faced the threat of malaria in diverse geographical locations and operational situations, resulting in considerable morbidity and mortality. However, because malaria may be transported out of endemic areas and into areas that are free of malaria, the threat doe...
journal_title:Military medicine
pub_type: 杂志文章
doi:10.7205/milmed.171.10.925
更新日期:2006-10-01 00:00:00
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journal_title:Military medicine
pub_type: 杂志文章
doi:10.7205/milmed.169.1.38
更新日期:2004-01-01 00:00:00
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journal_title:Military medicine
pub_type: 杂志文章
doi:10.7205/MILMED-D-15-00451
更新日期:2017-01-01 00:00:00
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journal_title:Military medicine
pub_type: 杂志文章,评审
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更新日期:2014-09-01 00:00:00
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journal_title:Military medicine
pub_type: 杂志文章
doi:10.1093/milmed/usaa409
更新日期:2020-11-16 00:00:00
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journal_title:Military medicine
pub_type: 杂志文章
doi:
更新日期:1996-03-01 00:00:00
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journal_title:Military medicine
pub_type: 杂志文章
doi:10.1093/milmed/usz257
更新日期:2020-01-07 00:00:00
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journal_title:Military medicine
pub_type: 杂志文章
doi:
更新日期:1990-12-01 00:00:00
abstract::Pneumothorax is a condition where air exists in the chest cavity, outside the lung. The causes of pneumothorax are numerous and determining the etiology can aid in treatment and prevent recurrence. We describe a 47-year-old female patient with past medical history of endometriosis who presented to the emergency room w...
journal_title:Military medicine
pub_type: 杂志文章
doi:10.1093/milmed/usz468
更新日期:2020-09-18 00:00:00
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journal_title:Military medicine
pub_type: 杂志文章
doi:10.7205/milmed-d-10-00370
更新日期:2011-03-01 00:00:00