Surgical management of growth hormone-secreting pituitary adenomas: A retrospective analysis of 33 patients.

Abstract:

:The endoscopic endonasal transsphenoidal approach (EETA) is the primary treatment for growth hormone (GH) adenoma. This study aimed to investigate the outcomes of EETA in 33 patients with GH-secreting pituitary adenoma (PA).Thirty-three patients who underwent EETA in Eighth People's Hospital of Shenzhen between January 2013 and December 2017 were included in the comprehensive analysis. Factors affecting the extent of resection and postoperative remission rates were also reviewed.The total cut rate was 63.6% (21), and the total remission rate was 66.7% (22) in all patients after surgery. The cure rate was 60.6% (20) for 33 patients. The total removal rate and remission rate were significantly different (P = .01, P = .007) for microadenomas, macroadenomas, and giant adenomas. In addition, the total removal rate and remission rate were significantly different (P = .004, P = .007) for patients with noninvasive and invasive GH-secreting PAs. Furthermore, there were significant differences (P = .003, P = .005) in the total removal rate and remission rate of patients with different preoperative GH levels. All patients with hypertension and diabetes mellitus were normalized. Three patients exhibited recurrence after surgery. Several patients suffered from postoperative complications, including transient diabetes insipidus in 3 (9.1%) patients and postoperative transient cerebrospinal fluid leakage in 2 (6.1%) patients.EETA is an effective therapeutic approach for treating patients with GH-secreting PA with high remission and low complication rates. Therefore, EETA should be considered a primary treatment for patients with GH-secreting PA.

journal_name

Medicine (Baltimore)

journal_title

Medicine

authors

Zheng Y,Chen DM,Wang Y,Mai RK,Zhu ZF

doi

10.1097/MD.0000000000019855

subject

Has Abstract

pub_date

2020-05-01 00:00:00

pages

e19855

issue

19

eissn

0025-7974

issn

1536-5964

pii

00005792-202005080-00007

journal_volume

99

pub_type

杂志文章

相关文献

MEDICINE文献大全
  • Silver dressings for the healing of venous leg ulcer: A meta-analysis and systematic review.

    abstract::This study was aimed to evaluate whether silver-containing dressings were superior to other types of dressings in the treatment of venous leg ulcers (VLU) and their specific advantages.Eight databases (Cochrane Library, PubMed, Web of Science, Ovid-Medline, Wanfang, VIP, China Biology Medicine, and China National Know...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000022164

    authors: Zhao M,Zhang D,Tan L,Huang H

    更新日期:2020-09-11 00:00:00

  • Delayed Intracerebral Hemorrhage Secondary to Ventriculoperitoneal Shunt: A Case Report and Literature Review.

    abstract::The ventriculoperitoneal (VP) shunt is a routine procedure for cerebrospinal fluid (CSF) diversion, and is associated with many complications. A delayed hemorrhage after the VP shunt surgery, however, is quite rare. In this study, we report a case involving late-onset hemorrhage. The 67-year-old male patient with a hi...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000002029

    authors: Ma L,Chen YL,Yang SX,Wang YR

    更新日期:2015-11-01 00:00:00

  • Comparison of oral versus intravenous tranexamic acid in total knee and hip arthroplasty: A GRADE analysis and meta-analysis.

    abstract:BACKGROUND:The efficacy and safety of oral tranexamic acid (TXA) remain controversial because of the small number of clinical studies. The aim of the present study was to compare the efficacy and safety of oral TXA with intravenous TXA in patients undergoing total hip arthroplasty and total knee arthroplasty in a syste...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000022999

    authors: Sun C,Zhang X,Chen L,Deng J,Ma Q,Cai X,Yang H

    更新日期:2020-10-30 00:00:00

  • The quality of life and readiness of Polish nurses to take new competences of drug prescribing.

    abstract::Satisfaction with life in the case of nurses is closely related to their professional work and is an important factor affecting the quality of work and patient care.An analysis of the readiness of Polish nurses depending on the level of life satisfaction.The study was conducted from January to November 2016 in randoml...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000012129

    authors: Marć M,Bartosiewicz A,Burzyńska J,Binkowska-Bury M,Januszewicz P

    更新日期:2018-09-01 00:00:00

  • Transcriptome analyses identify hub genes and potential mechanisms in adenoid cystic carcinoma.

    abstract::Adenoid cystic carcinoma (ACC) is one of the most frequent malignancies of salivary glands. The objective of this study was to identify key genes and potential mechanisms during ACC samples.The gene expression profiles of GSE88804 data set were downloaded from Gene Expression Omnibus. The GSE88804 data set contained 2...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000018676

    authors: Liu HB,Huang GJ,Luo MS

    更新日期:2020-01-01 00:00:00

  • ABO blood type, smoking status, other risk factors and prognosis of pancreatic ductal adenocarcinoma.

    abstract::The aim of this observational study was to test whether ABO blood type was a prognostic factor for pancreatic ductal adenocarcinoma (PDAC) patients and whether other risk factors could influence pancreatic cancer patients' survival. This study included 610 patients who were diagnosed as pancreatic cancer and had under...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000019413

    authors: Li SS,Zhou CY,Liao R,Xiong L,Weng NN,Zhao YQ,Mason C,Gou HF,Yi C,Zhu Q

    更新日期:2020-04-01 00:00:00

  • The effect of perigastric lipolymphatic tissue grouping by surgeon on the number of pathologic sampled lymph nodes after radical gastrectomy.

    abstract::To analyze the impact of perigastric lipolymphatic tissue grouping by the surgeon on the number of pathologic sampled lymph nodes and to explore the appropriate lymph node delivery process.The authors collected the medical records of gastric cancer patients who were hospitalized in Wuhan Union Hospital during the peri...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000011411

    authors: Cao Y,Xiong L,Deng S,Shen L,Li J,Wu K,Wang J,Tao K,Wang G,Cai K

    更新日期:2018-07-01 00:00:00

  • A randomized controlled trial on the impact of moderate-intensity continuous aerobic exercise on the depression status of middle-aged patients with congestive heart failure.

    abstract:BACKGROUND:Depression prevalence rates in congestive heart failure (CHF) patients have increased in the last few years. Depression is a leveled and independent risk factor for hospital readmission, decreased function, and patient mortality for patients with CHF. Major depressive disorder can be diagnosed in CHF patient...

    journal_title:Medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/MD.0000000000015344

    authors: Abdelbasset WK,Alqahtani BA

    更新日期:2019-04-01 00:00:00

  • Level of sensory block after spinal anesthesia as a predictor of hypotension in parturient.

    abstract::When the sensory block level (SBL) is ≥T5 or T4, a high incidence of hypotension occurs in parturients after spinal anesthesia. A rapidly ascending SBL is another risk factor for spinal anesthesia-induced hypotension. However, the relationship between the ascension rate of the SBL and spinal anesthesia-induced hypoten...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000007184

    authors: Zhang N,He L,Ni JX

    更新日期:2017-06-01 00:00:00

  • Safety of implantable Collamer lens implantation without ophthalmic viscosurgical device: A retrospective cohort study.

    abstract::To compare the safety of implantable Collamer lens (ICL) implantation with and without ophthalmic viscosurgical device (OVD).A total of 148 eyes underwent a conventional ICL implantation with OVD (OVD group), and 112 eyes underwent a modified ICL implantation without OVD (OVD-free group). The balanced salt solution wa...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000020691

    authors: Peng M,Tang Q,Zhao L,Khan MA,Lin D

    更新日期:2020-06-12 00:00:00

  • Comparison of intervertebral fusion rates of different bone graft materials in extreme lateral interbody fusion.

    abstract::To compare imaging indicators and clinical effects of extreme lateral interbody fusion (XLIF) using allogenic bone, autologous bone marrow + allogenic bone, and rhBMP-2 + allogenic bone as bone graft materials in the treatment of degenerative lumbar diseases.This was a retrospective study of 93 patients with lumbar in...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000017685

    authors: Gao Y,Li J,Cui H,Zhang F,Sun Y,Li Z,Ding W,Shen Y,Zhang W

    更新日期:2019-11-01 00:00:00

  • The first case report of a large deletion of the BRCA1 gene in Croatia: A case report.

    abstract:RATIONALE:Breast cancer is one of the most common cancers in women, and it is the leading cause of cancer related deaths in Croatia. BRCA1 and BRCA2 gene mutations are the most common cause of hereditary breast cancer. PATIENT CONCERNS:In this report we describe a Croatian patient with no apparent family history of ca...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000008667

    authors: Musani V,Sušac I,Ozretić P,Eljuga D,Levanat S

    更新日期:2017-12-01 00:00:00

  • Management of iatrogenic renal arteriovenous fistula and renal arterial pseudoaneurysm by transarterial embolization: A single center analysis and outcomes.

    abstract::The purpose of this study was to evaluate the efficacy and safety of transarterial embolization (TAE) for iatrogenic renal arterial pseudoaneurysm and arteriovenous fistula at our center.Our retrospective analysis included 27 patients who received TAE for iatrogenic renal arterial pseudoaneurysm and arteriovenous fist...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000008187

    authors: Guo H,Wang C,Yang M,Tong X,Wang J,Guan H,Song L,Zou Y

    更新日期:2017-10-01 00:00:00

  • A novel dermato-pulmonary syndrome associated with MDA-5 antibodies: report of 2 cases and review of the literature.

    abstract::Melanoma differentiation-associated protein 5 (MDA-5) is a novel autoantibody frequently characterized by interstitial lung disease and a distinct cutaneous phenotype with palmar papules, ulceration, and rash. Virtually all patients have underlying dermatomyositis, but many lack the characteristic clinical myopathy as...

    journal_title:Medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MD.0b013e3182606f0b

    authors: Chaisson NF,Paik J,Orbai AM,Casciola-Rosen L,Fiorentino D,Danoff S,Rosen A

    更新日期:2012-07-01 00:00:00

  • Congenital Nephrogenic Diabetes Insipidus Presented With Bilateral Hydronephrosis and Urinary Infection: A Case Report.

    abstract::Nephrogenic diabetes insipidus (NDI) is a condition resulting from the kidney's impaired response to circulating antidiuretic hormone (ADH), leading to polydipsia and polyuria. Urinary tract dilatation caused by NDI is a rare situation. Here, we report a case of congenital NDI presented with bilateral hydronephrosis.A...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000003464

    authors: Zheng K,Xie Y,Li H

    更新日期:2016-05-01 00:00:00

  • Clinical analysis of prenatal ultrasound diagnosis of fetal cardiovascular malformations in the first and second trimesters of pregnancy: A CARE-compliant article.

    abstract::Fetal cardiovascular malformations is widely focused and screened, but the accuracy of screening is not satisfactory. In this study, we compared the types of congenital heart malformation, accompanying diseases and fetal outcomes in the first and second trimesters of pregnancy to clarify the advantage of early screeni...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000016822

    authors: Han B,Li Y,Tang Y,Qu X,Wang F,Song H,Xu Y

    更新日期:2019-08-01 00:00:00

  • Probiotics, prebiotics, and synbiotics for the treatment of asthma: Protocol for a systematic review.

    abstract:BACKGROUND:Asthma is a common chronic disease with heavy burden. The number of asthma patients may continue to grow in the next 10 years. Existing conventional treatments have problems in which a small number of patients do not respond, often accompanied by side effects, or are too expensive. Probiotics, prebiotics, an...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000017840

    authors: Huang L,Guo J,Li W,Jiang M,Wang F,Kang J,Liu T,Gu X

    更新日期:2019-11-01 00:00:00

  • Clinicopathological significance of cystatin A expression in progression of esophageal squamous cell carcinoma.

    abstract::We previously conducted transcriptome analysis of a paired specimen of normal and esophageal squamous cell carcinoma (ESCC) tissues and found that mRNA expression of cystatin A (CSTA), a member of the cystatin superfamily, was perturbed in tumors compared with that in the background mucosa. However, little is known ab...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000010357

    authors: Shiba D,Terayama M,Yamada K,Hagiwara T,Oyama C,Tamura-Nakano M,Igari T,Yokoi C,Soma D,Nohara K,Yamashita S,Dohi T,Kawamura YI

    更新日期:2018-04-01 00:00:00

  • Infective Endocarditis and Cancer Risk: A Population-Based Cohort Study.

    abstract::This study investigated the possible relationship between endocarditis and overall and individual cancer risk among study participants in Taiwan.We used data from the National Health Insurance program of Taiwan to conduct a population-based, observational, and retrospective cohort study. The case group consisted of 14...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000003198

    authors: Sun LM,Wu JN,Lin CL,Day JD,Liang JA,Liou LR,Kao CH

    更新日期:2016-03-01 00:00:00

  • Influence of blood pressure variability on early carotid atherosclerosis in hypertension with and without diabetes.

    abstract::Carotid intima-media thickness (IMT) has been one widely used index of early carotid atherosclerosis. We speculated that the influence of blood pressure variability (BPV) on early carotid atherosclerosis may be varied by the location of the carotid artery and diabetes history. Thus, the goal of this study was to evalu...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000003864

    authors: Wu D,Li C,Chen Y,Xiong H,Tian X,Wu W,Huang W,Zhang YT,Zhang H

    更新日期:2016-06-01 00:00:00

  • Anterolateral tibial plateau osteotomy as a new approach for the treatment of posterolateral tibial plateau fracture: A case report.

    abstract:RATIONALE:It is challenging to visualize and reduce a posterolateral tibial plateau fracture through an anterolateral approach as the tibial plateau fragments are often covered by the fibular head and ligamentous structures. PATIENT CONCERNS:In this case report, we describe a patient with a depression fracture of the ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000009669

    authors: Sun DH,Zhao Y,Zhang JT,Zhu D,Qi BC

    更新日期:2018-01-01 00:00:00

  • Montelukast and budesonide combination for children with chronic cough-variant asthma.

    abstract::This study investigated the effectiveness and safety of montelukast combined budesonide (MCB) treatment for children with chronic cough-variant asthma (CCVA).In total, 82 cases of children with CCVA, aged 4 to 11 years were included in this study. All cases received either MCB or budesonide alone between May 2015 and ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000011557

    authors: Wang XP,Yang LD,Zhou JF

    更新日期:2018-07-01 00:00:00

  • Effect of sub-hypothermia blood purification technique in cardiac shock after valvular disease surgery.

    abstract::To observe the effect of sub-hypothermia (HT) blood purification technique in the treatment of cardiac shock after heart valve disease.The patients were randomly divided into normothermic (NT) continuous blood purification (CBP) group (NT group) and HT CBP group (HT group). Observe the cardiac index (CI), the oxygen d...

    journal_title:Medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/MD.0000000000019476

    authors: Fang J,Xu M,Liu B,Wang B,Ren H,Yang H,Dong Y,Song L,Xiao H

    更新日期:2020-03-01 00:00:00

  • Effects of dextrose prolotherapy on tendinopathy, fasciopathy, and ligament injuries, fact or myth?: A systematic review and meta-analysis.

    abstract:OBJECTIVES:Prolotherapy or proliferative therapy is a treatment option for damaged connective tissues involving the injection of a solution (proliferant) which theoretically causes an initial cell injury and a subsequent "proliferant" process of wound healing via modulation of the inflammatory process. Nonetheless, the...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000023201

    authors: Chung MW,Hsu CY,Chung WK,Lin YN

    更新日期:2020-11-13 00:00:00

  • Prognostic factors for patients with World Health Organization grade III meningiomas treated at a single center.

    abstract::We analyzed the characteristics of patients with World Health Organization (WHO) grade III meningioma to identify factors that may predict tumor recurrence and overall survival (OS).We retrospectively reviewed the patients diagnosed with WHO grade III meningioma who were surgically treated at our institute between 200...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000007385

    authors: Shan B,Zhang J,Song Y,Xu J

    更新日期:2017-06-01 00:00:00

  • Risk of hospitalization for hypoglycemia among older Korean people with diabetes mellitus: Interactions between treatment modalities and comorbidities.

    abstract::The objective of this study was to carry out a large population-based study to understand the factors associated with hypoglycemia-related hospitalizations among older Korean adults with diabetes mellitus.This study analyzed data from a subset of the 2013 Health Insurance and Review and Assessment service-Adult Patien...

    journal_title:Medicine

    pub_type: 杂志文章,多中心研究

    doi:10.1097/MD.0000000000005016

    authors: Kim HM,Seong JM,Kim J

    更新日期:2016-10-01 00:00:00

  • Type III Monteggia fracture with posterior interosseous nerve injury in a child: A case report.

    abstract:RATIONALE:Elbow injury in children by improper treatment or a delay of more than 3 weeks could lead to old unreduced Monteggia fracture, which are difficult to manage. Conservative or normal surgical methods usually fail. PATIENT CONCERNS:Herein, we present a 6-year-old boy with sustaining injury approximately 1 month...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000006377

    authors: Wang J,Chen M,Du J

    更新日期:2017-03-01 00:00:00

  • Association factor analysis between osteoporosis with cerebral artery disease: The STROBE study.

    abstract::The purpose of this study was to determine the clinical association factors between osteoporosis and cerebral artery disease in Korean population. Two hundred nineteen postmenopausal women and men undergoing cerebral computed tomography angiography were enrolled in this study to evaluate the cerebral artery disease by...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000006164

    authors: Jin ES,Jeong JH,Lee B,Im SB

    更新日期:2017-03-01 00:00:00

  • Rationale and design of a randomized trial of early intensive blood pressure lowering on cerebral perfusion parameters in thrombolysed acute ischemic stroke patients.

    abstract:BACKGROUND AND RATIONALE:Uncertainty persists over the optimal management of blood pressure (BP) in the early phase of acute ischemic stroke (AIS). This study aims to determine the safety and effects of intensive BP lowering on cerebral blood flow (CBF) and functional in AIS patients treated with intravenous thrombolys...

    journal_title:Medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/MD.0000000000012721

    authors: Sharma VK,Tan BYQ,Sim MY,Kulkarni A,Seow PA,Hong CS,Du Z,Wong LYH,Chen J,Chee EYH,Ng BSM,Low Y,Ngiam NJH,Yeo LLL,Teoh HL,Paliwal PR,Rathakrishnan R,Sinha AK,Chan BPL,Butcher K,Anderson CS

    更新日期:2018-10-01 00:00:00

  • Primary anorectal malignant melanoma: A case report.

    abstract:INTRODUCTION:Anorectal malignant melanoma (AMM) is a rare and aggressive malignance with poor prognosis, yet no consensus of treatment exists to date. Abdominoperineal resection surgery (APR) is the standard treatment of anorectal malignant melanoma, capable of controlling lymphatic spread and obtaining a large negativ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000019028

    authors: Xu X,Ge T,Wang G

    更新日期:2020-01-01 00:00:00