Abstract：
:This is the first controlled study regarding personality and psychopathology in adults with Noonan syndrome (NS). Anxiety, depression, alexithymia and symptoms of Attention Deficit-Hyperactivity Disorder and Autism Spectrum Disorder, have been previously described in NS. More information regarding personality and psychopathology in NS could improve mental health care for this population. Therefore, scores on the Minnesota Multiphasic Personality Inventory-2-Restructured Form (MMPI-2-RF), a widely used self-report questionnaire of personality and psychopathology, were compared between patients with NS (n = 18) and matched, healthy controls (n = 18). Furthermore, correlations between MMPI-2-RF scores and alexithymia, measured by the Toronto Alexithymia Scale-20, were investigated. Patients with NS showed significantly higher scores, with medium effect sizes, on MMPI-2-RF scales reflecting infrequent responses (F-r), somatic and cognitive complaints (FBS-r and RBS-r), internalizing problems (EID), demoralization (RCd) and introversion (INTR-r), although the overall profile in both groups was within the non-clinical range. Alexithymia correlated with internalizing problems and negative emotionality in the patient group. In conclusion, patients with NS showed higher levels of introversion, which may predispose them to internalizing problems. These problems were indeed more frequent in patients with NS, especially higher levels of demoralization. Patients may benefit from psychological interventions aimed to decrease internalizing problems, introversion and alexithymia.
journal_name
J Clin Psychol Med Settingsjournal_title
Journal of clinical psychology in medical settingsauthors
Roelofs RL,Wingbermühle E,van der Heijden PT,Jonkers R,de Haan M,Kessels RPC,Egger JIMdoi
10.1007/s10880-019-09659-7subject
Has Abstractpub_date
2020-06-01 00:00:00pages
256-267issue
2eissn
1068-9583issn
1573-3572pii
10.1007/s10880-019-09659-7journal_volume
27pub_type
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journal_title：Journal of clinical psychology in medical settings
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journal_title：Journal of clinical psychology in medical settings
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journal_title：Journal of clinical psychology in medical settings
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journal_title：Journal of clinical psychology in medical settings
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journal_title：Journal of clinical psychology in medical settings
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