CYTOGENETIC BIODOSIMETRY OF ACCIDENTAL EXPOSURES IN THE LONG TERMS AFTER IRRADIATION.

Abstract:

:The group of radiation victims who had received radiation injures similar to those of Chernobyl accident victims was evaluated in terms of retrospective cytogenetic biodosimetry in the long term period of from 17 y up to 50 y after irradiation. Based on the existing results of the long-term cytogenetic examination of the victims injured after the Chernobyl accident, an original method was developed. This method of retrospective dose recovery was based on the use of a special computer program, the time elapsed after irradiation and the frequency of atypical chromosomes. Both patient groups were examined using conventional cytogenetic analysis. The new method of a retrospective biodosimetry was tested on the non-Chernobyl group. As a result the multiple regression equations which included frequency atypical chromosomes produced better results because the majority of the estimates of the retrospective doses fell into the 95%-prediction intervals for the reference group of the Chernobyl victims.

journal_name

Radiat Prot Dosimetry

authors

Nugis VY,Kozlova MG,Nadejina NM,Galstyan IA,Nikitina VA,Khvostunov IK,Golub EV

doi

10.1093/rpd/ncz040

subject

Has Abstract

pub_date

2019-12-31 00:00:00

pages

31-36

issue

1

eissn

0144-8420

issn

1742-3406

pii

5445129

journal_volume

186

pub_type

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