Diagnosis of hereditary diffuse leukoencephalopathy with neuroaxonal spheroids based on next-generation sequencing in a family: Case report and literature review.

abstract：:Osteopetrosis, also known as marble bone disease, is a clinically rare genetic disease, which represents a heterogeneous group of rare, inherited bone dysplasias that share the hallmark of abnormally increased bone density caused by osteoclast dysfunction. Hereby, the authors describe a case of osteopetrosis that show...

journal_title：Medicine

authors： Zheng LC,OuYang XL,Liu GC,Zhang WJ,Zhang XM

更新日期：2015-06-01 00:00:00

abstract：:We aimed to detect novel genes associated with G protein-coupled receptors (GPCRs) in aldosterone-producing adenoma (APA) and elucidate the mechanisms underlying aldosterone production.Microarray analysis targeting GPCR-associated genes was conducted using APA without known mutations (APA-WT) samples (n = 3) and APA w...

journal_title：Medicine

authors： Kishimoto R,Oki K,Yoneda M,Gomez-Sanchez CE,Ohno H,Kobuke K,Itcho K,Kohno N

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:A rigid video-stylet intubation device provides safe and accurate access to the trachea by enabling visualization of the airway structures during tracheal intubation. The primary purpose of this study was to examine the effects of glycopyrrolate premedication on tracheal intubation with a rigid video-stylet....

journal_title：Medicine

authors： Cho EA,Hwang SH,Lee SH,Ryu KH,Kim YH

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:The requirement of postoperative bedridden and immobilization renders neurosurgical patients with higher risk of deep vein thrombosis (DVT), then more vulnerable for pulmonary thromboembolism (PTE). But silent pulmonary thromboembolism (SPTE) can be the very early stage of any typical form of PTE, its diagno...

journal_title：Medicine

authors： Tian R,Gao J,Chen A,Bao X,Guan J,Feng M,Li Y,Ma W,Ren Z,Wang R,Wei J

更新日期：2016-08-01 00:00:00

abstract：:To investigate the feasibility of 3D arterial spin labeling (ASL) as an alternative to dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) for the qualitative and quantitative evaluation of nasopharyngeal carcinoma (NPC) perfusion.Fifty-two newly diagnosed NPC patients underwent 3D ASL and DCE-MRI scans o...

journal_title：Medicine

authors： Xiao B,Wang P,Zhao Y,Liu Y,Ye Z

更新日期：2020-05-29 00:00:00

abstract：BACKGROUND:National Comprehensive Cancer Network (NCCN) guidelines recommend surgery, chemotherapy, and radiation therapy for gastric cancer patients. Neoadjuvant treatments as the administration of therapeutic agents before a main treatment gained in more and more attention. However, the role of neoadjuvant treatments...

journal_title：Medicine

authors： Long B,Yu ZY,Li Q,Du HR,Wang ZJ,Zhan H,Jiao ZY

更新日期：2018-04-01 00:00:00

abstract：:We analyzed the characteristics of patients with World Health Organization (WHO) grade III meningioma to identify factors that may predict tumor recurrence and overall survival (OS).We retrospectively reviewed the patients diagnosed with WHO grade III meningioma who were surgically treated at our institute between 200...

journal_title：Medicine

authors： Shan B,Zhang J,Song Y,Xu J

更新日期：2017-06-01 00:00:00

abstract：:The relevance of LP(a), Hcy, and D-D in ischemic cerebrovascular disease remains undefined. This study aimed to assess the associations of plasma LP(a), Hcy and D-D levels with the subtype of ischemic cerebrovascular disease.Patients with ischemic cerebrovascular disease admitted to the Taixing People's Hospital were ...

journal_title：Medicine

authors： Tang Y,Geng D

更新日期：2019-03-01 00:00:00

abstract：:The aim of this study was to compare bone mineral densities (BMDs) and body composition between Southeast Asia college students and Chinese college students, in order to provide a certain reference enhancing college students' physical fitness.A total of 1694 Chinese college students (294 men and 1400 women, aged 18-22...

journal_title：Medicine

authors： Liu P,Ye Z,Lu J,Lu H,Guan L,Teng Z,Gao S,Li M

更新日期：2016-09-01 00:00:00

abstract：:Traditionally, infective endocarditis (IE) has been microbiologically diagnosed by blood cultures or serology. However, conventional microbiologic methods do not always provide an etiologic diagnosis. We conducted the current study to evaluate the usefulness of a universal real-time polymerase chain reaction (PCR) of ...

journal_title：Medicine

authors： Marín M,Muñoz P,Sánchez M,Del Rosal M,Alcalá L,Rodríguez-Créixems M,Bouza E,Group for the Management of Infective Endocarditis of the Gregorio Marañón Hospital (GAME).

更新日期：2007-07-01 00:00:00

abstract：RATIONALE:Some patients with pulmonary arteriovenous malformation (PAVM) present with hypoxemia and life-threatening complications, including stroke and cerebral abscess. Catheter embolization is currently the preferred treatment for PAVM. However, previous studies have revealed that the incidence of PAVM recanalizatio...

journal_title：Medicine

authors： Takao S,Masuda T,Yamada T,Yamaguchi K,Sakamoto S,Matsushima H,Horimasu Y,Nakashima T,Miyamoto S,Iwamoto H,Fujitaka K,Hamada H,Hattori N

更新日期：2020-01-01 00:00:00

abstract：RATIONALE:Hypernatremia is a rare but fatal complication of hypertonic saline (HS) irrigation in hepatic hydatid disease. It needs careful monitoring and treatment. PATIENT CONCERNS:A 28-year-old woman with hepatic hydatid cysts who received operation treatment developed electrolyte disturbances. We also conducted a r...

journal_title：Medicine

authors： Zeng R,Wu R,Lv Q,Tong N,Zhang Y

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVE:This study was performed to explore the effects of probucol on contrast-induced acute kidney injury (CIAKI) in patients with coronary heart disease undergoing percutaneous coronary intervention (PCI). METHODS:In total, 220 patients undergoing PCI were randomly assigned to either the control group (hydration ...

journal_title：Medicine

authors： Wang Y,Shi Y,Xu X,Ge W,Yang S,Lu C

更新日期：2019-06-01 00:00:00

abstract：:The aim of this study was to determine whether there was a significant association between red blood cell distribution width (RDW) and uric acid (UA) in a large Chinese population.This was a cross-sectional study with an enrollment of 80,298 ostensibly healthy participants (48,971 males, 31,327 females) during the per...

journal_title：Medicine

authors： Zhang C,Meng Z,Li X,Liu M,Ren X,Zhu M,He Q,Zhang Q,Song K,Jia Q,Chen Q

更新日期：2018-10-01 00:00:00

abstract：RATIONALE:Nivolumab is a monoclonal IgG antibody blocking programmed death receptor-1 (PD1), leading to restoration of the natural T-cell-mediated immune response against the cancer cells. However, it also causes plenty of autoimmune-related adverse events, which often involves endocrine system. PATIENT CONCERNS:A 54-...

journal_title：Medicine

authors： Zeng MF,Chen LL,Ye HY,Gong W,Zhou LN,Li YM,Zhao XL

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Randomized trials and observation studies have revealed conflicting results regarding the interaction between clopidogrel and proton pump inhibitors (PPIs). The aim of our study was to provide laboratory evidence regarding whether PPIs blunt the antiplatelet reactivity of clopidogrel. METHODS:We included re...

journal_title：Medicine

authors： Lin SF,Lin PC,Chang CC,Chang WL,Chu FY

更新日期：2020-12-11 00:00:00

abstract：:Pneumonic-type adenocarcinoma (P-ADC) is a subtype of lung adenocarcinoma with high mortality, which often requires lobectomy surgery. Nonsurgically treated P-ADC patients usually have more advanced or complex conditions, which remain poorly understood and pose a major challenge in clinical management. We aimed to des...

journal_title：Medicine

authors： Wei J,Tang D,Nie Y,Chen J,Peng L

更新日期：2019-05-01 00:00:00

abstract：:Although remifentanil is used widely by many clinicians during general anesthesia, there are recent evidences of opioid-induced hyperalgesia as an adverse effect. This study aimed to determine if intraoperative remifentanil infusion caused increased pain during the postoperative period in patients who underwent a thyr...

journal_title：Medicine

authors： Jo JY,Choi SS,Yi JM,Joo EY,Kim JH,Park SU,Sim JH,Karm MH,Ku S

更新日期：2016-02-01 00:00:00

abstract：:The aim of the study was to investigate diagnosis efficacy of dynamic contrast-enhanced MRI (DCE-MRI) and diffusion-weighted MRI (DW-MRI) in Crohn's disease (CD). To find out the correlations between functional MRI parameters including K, Kep, Ve, Vp, and apparent diffusion coefficient (ADC) with a serologic biomarker...

journal_title：Medicine

authors： Zhu J,Zhang F,Luan Y,Cao P,Liu F,He W,Wang D

更新日期：2016-04-01 00:00:00

abstract：:Although the precise mechanisms underlying the pathogenesis of abdominal aortic aneurysm (AAA) remain unclear, aortic wall inflammation has been implicated in AAA development. Several studies have reported the use of fluoro-deoxyglucose (F-FDG)/positron emission tomography (PET) to assess the nature of AAA.We present ...

journal_title：Medicine

authors： Tsuruda T,Nagamachi S,Nishimura M,Nakamura K,Kitamura K

更新日期：2016-05-01 00:00:00

abstract：RATIONALE:According to previously published studies, treating pediatric patients with congenital pseudarthrosis of the tibia (CPT) is challenging. More effective methods are needed to treat this patient population. PATIENT CONCERNS:A 7-year-old girl with congenital pseudarthrosis of the distal tibia, previously misdia...

journal_title：Medicine

authors： Kong LD,Cheng HX,Nie T

更新日期：2018-12-01 00:00:00

abstract：:Serum adiponectin levels have been suggested to be predictors of type 2 diabetes mellitus in diverse populations. However, the relationship between circulating adiponectin levels and the risk of development of type 2 diabetes in postmenopausal women has not been investigated.A total of 382 healthy postmenopausal women...

journal_title：Medicine

authors： Darabi H,Raeisi A,Kalantarhormozi MR,Ostovar A,Assadi M,Asadipooya K,Vahdat K,Dobaradaran S,Nabipour I

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Pain in glossodynia may be severe; it may prevent patients from working, interfere with daily life activities, and necessitate a patient's visit to a medical institution for consultation and treatment. The pain may be described as persistent and burning (tingling, tingling) or stinging. Patients may complain...

journal_title：Medicine

authors： Ayuse T,Okayasu I,Tachi-Yoshida M,Sato J,Saisu H,Shimada M,Yamazaki Y,Imura H,Hosogaya N,Nakashima S

更新日期：2020-08-14 00:00:00

abstract：:This study aimed to assess the associations of human leukocyte antigen (HLA)-DR and interleukin (IL)-18 gene polymorphisms with hepatitis B virus (HBV).Clinical data were retrospectively reviewed between December 2006 and December 2015 at Xiangyang Central Hospital. HBV patients were assigned to the high and low viral...

journal_title：Medicine

authors： Jiang H,Cao F,Cao H,Rao Q,Yang Y

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:This systematic review aims to evaluate the efficacy of Gegen Qinlian Decoction (GQD) for ulcerative colitis (UC). METHODS:PubMed, EMBASE, Springer LINK, Cochrane Library, the China National Knowledge Infrastructure, Chongqing Weipu Database for Chinese Technical Periodicals, Wan-fang Database, and Chinese ...

journal_title：Medicine

authors： Fan Y,Yi W,Huang H,Mei Z,Feng Z

更新日期：2019-12-01 00:00:00

abstract：:The Glasgow-Blatchford scores (GBS) and Rockall scores (RS) are commonly used for stratifying patients with nonvariceal upper gastrointestinal hemorrhage (NVUGIH). Although predictive value of these scoring methods has been extensively validated, their clinical effectiveness remains unclear. The following study evalua...

journal_title：Medicine

authors： Lu M,Sun G,Huang H,Zhang X,Xu Y,Chen S,Song Y,Li X,Lv B,Ren J,Chen X,Zhang H,Mo C,Wang Y,Yang Y

更新日期：2019-05-01 00:00:00

abstract：RATIONALE:IgG4-related disease (IgG4-RD) is an emerging immune-mediated disease characterized by multi-organ involvement and variable clinical behavior. PATIENT CONCERNS:We describe the case of a 50-year-old woman affected by a rare variant of IgG4-RD, characterized by eyelid xanthelasmas, adult-onset asthma and saliv...

journal_title：Medicine

authors： Pomponio G,Olivari D,Mattioli M,Angeletti A,Rossetti G,Goteri G,Gabrielli A

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:To investigate the effect of neck-specific exercise with (NSEB) or without (NSE) a behavioural approach and prescribed physical activity (PPA) on general pain disability and psychological factors in chronic whiplash-associated disorders (WAD), grade 2 and 3, with a 2-year follow-up. METHODS:A randomized con...

journal_title：Medicine

authors： Overmeer T,Peterson G,Landén Ludvigsson M,Peolsson A

更新日期：2016-08-01 00:00:00

abstract：:Hand-foot-and-mouth disease (HFMD) is a common childhood infection that may lead to serious complications and even death. Globally, epidemics of HFMD are increasing each year, especially in China. This study aimed to identify risk factors for death in children with critical and severe HFMD in Chongqing, China.We perfo...

journal_title：Medicine

authors： Zheng G,Cao J,Yu J,Zhang Z,Liu Q,Chen J

更新日期：2017-12-01 00:00:00

abstract：:The aim of this study was to assess the stress-related responses and the coach's capability to match perceived efforts of youth athletes during a taekwondo championship.Using a cross-sectional study design, salivary cortisol (sC) and alpha-amylase (sAA) were measured in 6 males and 3 females young (11.0 ± 0.9 years) a...

journal_title：Medicine

authors： Capranica L,Condello G,Tornello F,Iona T,Chiodo S,Valenzano A,De Rosas M,Messina G,Tessitore A,Cibelli G

更新日期：2017-07-01 00:00:00