Abstract:
:Deleterious mutations accumulating on non-recombining Y chromosomes can drive XY to XY turnovers, as they allow to replace the old mutation-loaded Y by a new mutation-free one. The same process is thought to prevent XY to ZW turnovers, because the latter requires fixation of the ancestral Y, assuming dominance of the emergent feminizing mutation. Using individual-based simulations, we explored whether and how an epistatically dominant W allele can spread in a young XY system that gradually accumulates deleterious mutations. We also investigated how sexually antagonistic (SA) polymorphism on the ancestral sex chromosomes and the mechanism controlling X-Y recombination suppression affect these transitions. In contrast with XY to XY turnovers, XY to ZW turnovers cannot be favored by Y chromosome mutation load. If the arrest of X-Y recombination depends on genotypic sex, transitions are strongly hindered by deleterious mutations, and totally suppressed by very small SA cost, because deleterious mutations and female-detrimental SA alleles would have to fix with the Y. If, however, the arrest of X-Y recombination depends on phenotypic sex, X and Y recombine in XY ZW females, allowing for the purge of Y-linked deleterious mutations and loss of the SA polymorphism, causing XY to ZW turnovers to occur at the same rate as in the absence of deleterious and sex-antagonistic mutations. We generalize our results to other types of turnovers (e.g., triggered by non-dominant sex-determining mutations) and discuss their empirical relevance.
journal_name
Heredity (Edinb)journal_title
Heredityauthors
Saunders PA,Neuenschwander S,Perrin Ndoi
10.1038/s41437-019-0225-zsubject
Has Abstractpub_date
2019-09-01 00:00:00pages
419-428issue
3eissn
0018-067Xissn
1365-2540pii
10.1038/s41437-019-0225-zjournal_volume
123pub_type
杂志文章相关文献
HEREDITY文献大全abstract::We investigated genetic diversity among and within natural populations of Asian common wild rice, Oryza rufipogon, from three different classes of data: quantitative traits, allozymes, and restriction fragment length polymorphisms (RFLPs). The seven populations examined showed polymorphism to varying degrees. The amou...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/sj.hdy.6800435
更新日期:2004-05-01 00:00:00
abstract::Growth rate of 12 groups of common carp was measured at five experimental environments. Three of the 12 tested groups were strains of the domesticated European race of the common carp, one group was a representative of the Big-Belly Chinese race, and the remaining eight groups were F1 crossbreds among the European str...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/hdy.1975.42
更新日期:1975-06-01 00:00:00
abstract::Geographical patterns of gene flow and drift were analysed in the commensal cellar spider Pholcus phalangioides to get insight into the causes affecting genetic variation in this species strictly associated with man. Our sampling consisted of 23 subpopulations collected over five urban regions in central Europe (dista...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1046/j.1365-2540.2001.00815.x
更新日期:2001-01-01 00:00:00
abstract::Genomic rearrangements can result in losses, amplifications, translocations and inversions of DNA fragments thereby modifying genome architecture, and potentially having clinical consequences. Many genomic disorders caused by structural variation have initially been uncovered by early cytogenetic methods. The last dec...
journal_title:Heredity
pub_type: 杂志文章,评审
doi:10.1038/hdy.2011.100
更新日期:2012-01-01 00:00:00
abstract::Galton's ancestral law states that the two parent contribute between them on average one-half of the total heritage of the offspring, the four grandparents one-quarter, and so on. He interpreted this law both as a representation of the separate contributions of each ancestor to the heritage of the offspring and as a m...
journal_title:Heredity
pub_type: 传,历史文章,杂志文章
doi:10.1046/j.1365-2540.1998.00418.x
更新日期:1998-11-01 00:00:00
abstract::The availability of whole genome sequencing (WGS) data enables the discovery of causative single nucleotide polymorphisms (SNPs) or SNPs in high linkage disequilibrium with causative SNPs. This study investigated effects of integrating SNPs selected from imputed WGS data into the data of 54K chip on genomic prediction...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/s41437-019-0246-7
更新日期:2020-01-01 00:00:00
abstract::Genomic selection has become a reality in plant breeding programs with the reduction in genotyping costs. Especially in maize breeding programs, it emerges as a promising tool for predicting hybrid performance. The dynamics of a commercial breeding program involve the evaluation of several traits simultaneously in a l...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/s41437-020-0321-0
更新日期:2020-08-01 00:00:00
abstract::Understanding genetic mechanisms of self-incompatibility (SI) and how they evolve is central to understanding the mating behaviour of most outbreeding angiosperms. Sporophytic SI (SSI) is controlled by a single multi-allelic locus, S, which is expressed in the diploid (sporophyte) plant to determine the SI phenotype o...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/hdy.2010.29
更新日期:2011-01-01 00:00:00
abstract::We examine seven geographically separate subpopulations of Heliconius charithonia, a butterfly with well-documented home range behaviour, in Miami-Dade County, Florida, for genetic differentiation using cellulose acetate electrophoresis. These subpopulations exhibit little genetic variation (percent polymorphic loci =...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1046/j.1365-2540.2001.00830.x
更新日期:2001-02-01 00:00:00
abstract::Elucidating barriers to gene flow is important for understanding the dynamics of speciation. Here we investigate pre- and post-zygotic mechanisms acting between the two hybridizing species of Atlantic eels: Anguilla anguilla and A. rostrata. Temporally varying hybridization was examined by analyzing 85 species-diagnos...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/hdy.2016.96
更新日期:2017-03-01 00:00:00
abstract::Understanding the evolution of female multiple mating (polyandry) is crucial for understanding sexual selection and sexual conflict. Despite this interest, little is known about its genetic basis or whether genetics influences the evolutionary origin or maintenance of polyandry. Here, we explore the quantitative genet...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/sj.hdy.6800897
更新日期:2007-02-01 00:00:00
abstract::Rainforests in Australia and around the world have been extensively cleared and degraded. It is essential to recognize the changes in population diversity and dynamics that follow habitat fragmentation if better conservation and management strategies are to be developed. This study is an investigation of the medium te...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/sj.hdy.6800585
更新日期:2004-12-01 00:00:00
abstract::Temperature-dependent sex determination (TSD) was first reported in 1966 in an African lizard. It has since been shown that TSD occurs in some fish, several lizards, tuataras, numerous turtles and all crocodilians. Extreme temperatures can also cause sex reversal in several amphibians and lizards with genotypic sex de...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/hdy.2010.102
更新日期:2011-04-01 00:00:00
abstract::Investigations into the genetic basis of reproductive barriers among recognized and putative varieties in Phacelia dubia have provided evidence that even among closely related taxa, multiple pathways can lead to reproductive isolation. A nuclear-based reproductive barrier, expressed as partial hybrid sterility of both...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/hdy.1991.97
更新日期:1991-12-01 00:00:00
abstract::The frequency of B chromosomes has been determined for several stages in the grasshopper life-cycle, over three generations, in three natural populations spanning a steep cline in East Anglia. This has revealed a rise in B frequency in prediapause eggs, a fall during the winter in the embryos and a rise in the early n...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/hdy.1976.47
更新日期:1976-06-01 00:00:00
abstract::North Africa is now recognized as a major area for the emergence and dispersal of anatomically modern humans from at least 315 kya. The Mediterranean Basin is thus particularly suited to study the role of climate versus human-mediated changes on the evolutionary history of species. The Algerian mouse (Mus spretus Lata...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/s41437-018-0089-7
更新日期:2019-02-01 00:00:00
abstract::Genetic diversity is a fundamental requirement for evolution and adaptation. Nonetheless, the forces that maintain patterns of genetic variation in wild populations are not completely understood. Neutral theory posits that genetic diversity will increase with a larger effective population size and the decreasing effec...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/hdy.2015.76
更新日期:2016-01-01 00:00:00
abstract::Knowledge about the underlying genetic architecture of phenotypic traits is needed to understand and predict evolutionary dynamics. The number of causal loci, magnitude of the effects and location in the genome are, however, still largely unknown. Here, we use genome-wide single-nucleotide polymorphism (SNP) data from...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/hdy.2017.29
更新日期:2017-09-01 00:00:00
abstract::Environmental stress generally exacerbates the harmful effects of inbreeding and it has been proposed that this could be exploited in purging deleterious alleles from threatened inbred populations. However, understanding what factors contribute to variability in the strength of inbreeding depression (ID) observed acro...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/hdy.2015.103
更新日期:2016-03-01 00:00:00
abstract::Many herbicide-resistant weed species are polyploids, but far too little about the evolution of resistance mutations in polyploids is understood. Hexaploid wild oat (Avena fatua) is a global crop weed and many populations have evolved herbicide resistance. We studied plastidic acetyl-coenzyme A carboxylase (ACCase)-in...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/hdy.2012.69
更新日期:2013-03-01 00:00:00
abstract::To address the multiple challenges to food security posed by global climate change, population growth and rising incomes, plant breeders are developing new crop varieties that can enhance both agricultural productivity and environmental sustainability. Current breeding practices, however, are unable to keep pace with ...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/hdy.2015.113
更新日期:2016-04-01 00:00:00
abstract::We have used the polymerase chain reaction (PCR) and restriction fragment length polymorphism (RFLP) techniques to design two genetic markers for blue mussels in the Mytilus edulis species complex. Both of these markers target the gene encoding the mussel polyphenolic adhesive protein. The first marker, Glu-5', is hig...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/hdy.1996.187
更新日期:1996-12-01 00:00:00
abstract::Assessing in wild populations how fitness is impacted by inbreeding and genetic drift is a major goal for conservation biology. An approach to measure the detrimental effects of inbreeding on fitness is to estimate correlations between molecular variation and phenotypic performances within and among populations. Our s...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/hdy.2012.110
更新日期:2013-04-01 00:00:00
abstract::How do morphological differences between species evolve at the genetic level? This study investigates the genetic basis of recent divergence in male wing size between species of the model parasitoid wasp Nasonia. The forewings of flightless Nasonia vitripennis males are 2.3 times smaller than males of their flighted s...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/hdy.2009.146
更新日期:2010-03-01 00:00:00
abstract::In the mosquito Culex pipiens, over-production of esterases is a common insecticide resistance mechanism. Different alleles at the esterase A and B loci are known to occur in natural populations, as shown by enzyme electrophoresis and RFLP studies on the esterase B locus. Here we analyse the variability of the esteras...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/hdy.1996.181
更新日期:1996-11-01 00:00:00
abstract::In the semienclosed Adriatic Sea, the shared stocks of the cephalopods Loligo vulgaris and Sepia officinalis represent important marine fisheries resources exploited by all coastal countries. The improving of knowledge on the demographic features of these shared stocks is internationally relevant for adopting responsi...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/sj.hdy.6800489
更新日期:2004-08-01 00:00:00
abstract::How life-history strategies influence the evolution of populations is not well understood. Most existing models stem from the Wright-Fisher model which considers discrete generations and a fixed population size, thus not taking into account any potential consequences of overlapping generations and demographic stochast...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/s41437-018-0118-6
更新日期:2018-10-01 00:00:00
abstract::Stable hybrid zones in which ecologically divergent taxa give rise to a range of recombinants are natural laboratories in which the genetic basis of adaptation and reproductive isolation can be unraveled. One such hybrid zone is formed by the fire-bellied toads Bombina bombina and B. variegata (Anura: Discoglossidae)....
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/sj.hdy.6800291
更新日期:2003-08-01 00:00:00
abstract::Podisma pedestris exists as both an XO and neoXY form in the Southern French Alps. These chromosome types are shown to be contiguously allopatric and hybrid populations have been located in several places. Hybridisation appears to be occurring freely, but the hybrid zones are quite narrow. In several places the two di...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/hdy.1975.108
更新日期:1975-12-01 00:00:00
abstract::Evolution of the rDNA spacer, ITS 2, is examined by comparing 17 DNA sequences of the ticks, Ixodes scapularis and I. pacificus. The distribution of fixed interspecific differences and the relative frequency of base changes vs. insertions/deletions (indels) matches the distribution and relative frequency for intraspec...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/hdy.1995.139
更新日期:1995-09-01 00:00:00