Evaluation of strategy for testing thyroid function applied to hypothyroidism.

abstract：PURPOSE:To investigate p53 and hepatoma-derived growth factor (HDGF) expression and their association with clinicopathological features of Ewing family tumour (EFT). EXPERIMENTAL DESIGN:A total of 108 cases of EFT were retrospectively analysed. p53 and HDGF expression were detected using immunohistochemistry, and the ...

journal_title：Journal of clinical pathology

authors： Yang Y,Zhen T,Zhang F,Dai S,Kang L,Liang Y,Xue L,Han A

更新日期：2014-03-01 00:00:00

abstract：:A patient with chronic granulomatous disease who was being treated with steroids was diagnosed with a soft tissue Scedosporium apiospermum infection. Despite extensive treatment with antifungals progression to involve solid tissue (bone) occurred. Treatment required an HLA matched bone marrow transplant, which led to ...

journal_title：Journal of clinical pathology

authors： Gompels MM,Bethune CA,Jackson G,Spickett GP

更新日期：2002-10-01 00:00:00

abstract：:Forty six lymph nodes were examined with the indirect immunoperoxidase technique for the distribution of fibronectin and laminin. Fibronectin was present in the framework of the tissue and the basal lamina of blood vessels, giving a clear outline of nodal architecture. Intracellular fibronectin was observed in cases o...

journal_title：Journal of clinical pathology

authors： Reilly JT,Nash JR,Mackie MJ,McVerry BA

更新日期：1985-08-01 00:00:00

abstract：:The sellar region is the site of a large number of pathological entities arising from the pituitary and adjacent anatomical structures, including brain, blood vessels, nerves and meninges. The surgical pathology of this area requires the accurate identification of neoplastic lesions, including pituitary adenoma and ca...

journal_title：Journal of clinical pathology

authors： Al-Brahim NY,Asa SL

更新日期：2006-12-01 00:00:00

abstract：AIMS:The assessment of lymphatic vessel density (LVD) has been suggested as a tool to determine the metastatic risk of neoplasias. On this premise, the authors aimed to verify whether progression risk of stage I colorectal cancer may be related to LVD. The authors also evaluated and correlated vascular endothelial grow...

journal_title：Journal of clinical pathology

authors： Barresi V,Reggiani-Bonetti L,Di Gregorio C,De Leon MP,Barresi G

更新日期：2011-01-01 00:00:00

abstract：:Xanthine oxidase (XO) activity was found to be negligible in sterile human urines (less than 480 units, as presently defined, per litre). Significant XO activity was found in all urines containing more than 10(5) bacteria/ml, except for urines infected with Staphylococcus aureus, in which XO activity ranged from 347 t...

journal_title：Journal of clinical pathology

authors： Giler S,Henig EF,Urca I,Sperling O,de Vries A

更新日期：1978-05-01 00:00:00

abstract：:During a two-year period of observation Bacteroides species were isolated from specimens of pus and vaginal swabs from 115 patients in this hospital. Thirty-five representative strains proved on examination to be Bacteroides fragilis. Minimal inhibitory and minimal bactericidal concentrations of six antibiotics for th...

journal_title：Journal of clinical pathology

authors： Ingham HR,Selkon JB,Codd AA,Hale JH

更新日期：1968-07-01 00:00:00

abstract：:In patients with chronic renal failure, blood samples for laboratory analysis are often taken via dialysis catheters. This report describes a case of gross spurious hypernatraemia in a blood sample collected from a patient undergoing haemodialysis. After centrifugation of the blood sample in question, the separator ge...

journal_title：Journal of clinical pathology

authors： Srivastava R,Murphy MJ,Card J,Severn A,Fraser CG

更新日期：2004-12-01 00:00:00

abstract：AIMS:To investigate the role of needle core biopsy (NCB) in the preoperative assessment of impalpable breast lesions, mainly derived from the NHS Breast Screening Programme (NHSBSP) and to assess our own modifications to a suggested system for the classification of breast NCBs. METHODS:The NCB, fine needle aspiration ...

journal_title：Journal of clinical pathology

authors： Ibrahim AE,Bateman AC,Theaker JM,Low JL,Addis B,Tidbury P,Rubin C,Briley M,Royle GT

更新日期：2001-02-01 00:00:00

abstract：:The biochemical assay for the oestrogen receptor has shown the clinical value of knowing the concentration of the receptor within tissue. The immunohistochemical assay is rapidly taking over from the biochemical assay. Therefore, it is vital to have an equivalent scoring system that will have the same predictive value...

journal_title：Journal of clinical pathology

authors： Leake R,Barnes D,Pinder S,Ellis I,Anderson L,Anderson T,Adamson R,Rhodes T,Miller K,Walker R

更新日期：2000-08-01 00:00:00

abstract：:Factor VIII-containing materials were administered to four severely affected haemophiliacs twice weekly in doses calculated to raise the factor VIII level to either 15% or 30% of average normal. The pooled results from those patients with statistically similar baseline bleeding frequencies showed a significant reducti...

journal_title：Journal of clinical pathology

authors： Aronstam A,Kirk PJ,McHardy J,Culver-James JW,McLellan DS,Turk P,Rainsford SG,Slattery M

更新日期：1977-01-01 00:00:00

abstract：AIMS:To determine the causes of death in patients with osteogenesis imperfecta, excluding infants with the perinatal lethal form (type II). METHODS:Seventy nine patients with known osteogenesis imperfecta were identified, 37 of whom had been seen clinically in life. Causes of death were identified from death certifica...

journal_title：Journal of clinical pathology

authors： McAllion SJ,Paterson CR

更新日期：1996-08-01 00:00:00

abstract：AIM:Thalassaemia is a good candidate disease for control by preventive genetic programmes in developing countries. Accurate population frequency data are needed for planning the control of thalassaemia in the high risk Guangdong Province of southern China. METHODS:In total, 13397 consecutive samples from five geograph...

journal_title：Journal of clinical pathology

authors： Xu XM,Zhou YQ,Luo GX,Liao C,Zhou M,Chen PY,Lu JP,Jia SQ,Xiao GF,Shen X,Li J,Chen HP,Xia YY,Wen YX,Mo QH,Li WD,Li YY,Zhuo LW,Wang ZQ,Chen YJ,Qin CH,Zhong M

更新日期：2004-05-01 00:00:00

abstract：:Campylobacter pyloridis is a spiral bacterium which was seen by histopathologists several years before it was cultured in 1982 in Perth, Western Australia. It has unique cellular fatty acids, predominantly tetradecanoic acid and cis-11, 12 methylene octadecanoic acid. It also has a unique ultrastructure which is diffe...

journal_title：Journal of clinical pathology

authors： Goodwin CS,Armstrong JA,Marshall BJ

更新日期：1986-04-01 00:00:00

abstract：:Two groups of women with non-specific genital infection were treated for two weeks with tetracycline 250 mg six-hourly and minocycline 100 mg twice daily respectively. Cultures for yeasts were performed before treatment and at the end of the first and second weeks. Before treatment yeasts, mostly Candida albicans, wer...

journal_title：Journal of clinical pathology

authors： Oriel JD,Waterworth PM

更新日期：1975-05-01 00:00:00

abstract：OBJECTIVES:To determine whether antibiotics are prescribed appropriately for acute tonsillitis in an emergency department (ED). METHODS:Cross-sectional observational study in large district general hospital in London. Patients diagnosed and coded with 'acute tonsillitis' in the ED over a 3-month period in 2015. Medica...

journal_title：Journal of clinical pathology

authors： Kanji K,Saatci D,Rao GG,Khanna P,Bassett P,Williams B,Khan M

更新日期：2016-09-01 00:00:00

abstract：:Candida spp are the fourth most common group of nosocomial pathogens isolated from patients on medical, surgical, and intensive care wards. Polymicrobial candidaemia has rarely been described. The diagnosis of candidaemia from peripheral blood smears has not been widely reported. This report describes the case of a yo...

journal_title：Journal of clinical pathology

authors： Yera H,Poulain D,Lefebvre A,Camus D,Sendid B

更新日期：2004-02-01 00:00:00

abstract：:Cell surface proteolysis is an important mechanism for generating biologically active proteins that mediate a range of cellular functions and contribute to biological processes such as angiogenesis. Although most studies have focused on the plasminogen system and matrix metalloproteinases (MMPs), recently there has be...

journal_title：Journal of clinical pathology

authors： Noel A,Maillard C,Rocks N,Jost M,Chabottaux V,Sounni NE,Maquoi E,Cataldo D,Foidart JM

更新日期：2004-06-01 00:00:00

abstract：:One hundred and twenty-one rectal biopsies from 99 patients with carcinoma of the rectum or lower sigmoid colon were investigated using a high iron-diamine-Alcian blue technique for sulphated and non-sulphated acid mucins. It was found that in normal rectal mucosa sulphomucins are the main carbohydrate component of th...

journal_title：Journal of clinical pathology

authors： Filipe MI

更新日期：1972-02-01 00:00:00

abstract：:Colonising Campylobacter pyloridis were identified histologically in gastric biopsy specimens from 89% of 83 patients with non-ulcer dyspepsia and chronic gastritis, but not in 58 dyspeptic patients with normal mucosa. The presence and population density of organisms was associated with the presence of intraepithelial...

journal_title：Journal of clinical pathology

authors： Wyatt JI,Rathbone BJ,Heatley RV

更新日期：1986-08-01 00:00:00

abstract：AIMS:Heightened B-cell receptor (BCR) activity in diffuse large B-cell lymphoma (DLBCL) is well established, and a subset of patients with relapsed DLBCL can benefit from BCR-targeted therapies. Universal outreach of such emerging therapies mandates forming a global landscape of BCR molecular signalling in DLBCL, inclu...

journal_title：Journal of clinical pathology

authors： Masir N,Akhter A,Roshan TM,Florence CS,Abdul-Rahman F,Tumian NR,Kean-Chang P,Elyamany G,Shabani-Rad MT,Mansoor A

更新日期：2019-09-01 00:00:00

abstract：AIMS:Inflammatory bowel disease (IBD)-associated precancerous lesions may be adenomatous or non-adenomatous with various histomorphologies. We aim to validate the newly proposed classification, to explore the neoplastic nature of the non-adenomatous lesions and to elucidate the molecular mechanisms underlying the diffe...

journal_title：Journal of clinical pathology

authors： Gui X,Köbel M,Ferraz JG,Iacucci M,Ghosh S,Liu S,Ou Y,Perizzolo M,Winkfein RJ,Rambau P,Demetrick DJ

更新日期：2020-07-01 00:00:00

abstract：:The development of sensitive reagents and detection systems, together with the introduction of heat-induced antigen retrieval, has rapidly entrenched immunohistology as an indispensable adjunct to routine histological examination, contributing to diagnosis, prognosis and treatment. New antibodies continue to be produc...

journal_title：Journal of clinical pathology

authors： Leong AS,Leong TY

更新日期：2006-11-01 00:00:00

abstract：:Endocardial fibroelastosis, defined as an endocardium in excess of 30 microns thick, was found in 10 out of 34 cases of hydrops fetalis in a review of 1589 perinatal necropsies carried out between 1976 and 1989. The infants comprised 16 cases of rhesus haemolytic disease, of whom three had endocardial fibroelastosis, ...

journal_title：Journal of clinical pathology

authors： Newbould MJ,Armstrong GR,Barson AJ

更新日期：1991-07-01 00:00:00

abstract：:Michaëlsson's (1961) method for the measurement of plasma bilirubin concentration was found to be complicated by conjugated bilirubin. Delaying the addition of the accelerator, diphylline, corrected this fault. The method was calibrated using serum or plasma, since reconstituted protein solutions introduced large erro...

journal_title：Journal of clinical pathology

authors： Thompson RP

更新日期：1969-07-01 00:00:00

abstract：:Advanced non-small cell lung cancer samples are tested for epidermal growth factor receptor (EGFR) gene mutations. Their detection by direct sequencing is time-consuming. Conversely, the length analysis of fluorescently labelled PCR products is easier. To avoid labelled primers and the automated capillary electrophore...

journal_title：Journal of clinical pathology

authors： Malapelle U,Russo S,Pepe F,Sgariglia R,De Luca C,Bellevicine C,Pallante P,Troncone G

更新日期：2013-11-01 00:00:00

abstract：:A rapidly fatal case of enteritis necroticans in a 24 year old man with diabetes was caused by Clostridium perfringens type C. The role of beta toxin in the disease is discussed. This type has not been previously described as a causative agent in necrotising bowel disease of man outside endemic areas. ...

journal_title：Journal of clinical pathology

authors： Severin WP,de la Fuente AA,Stringer MF

更新日期：1984-08-01 00:00:00

abstract：:A total of 104 clinical isolates of Pr. mirabilis from three hospitals were screened for their sensitivity to chlorhexidine. The minimum inhibitory concentrations of the antiseptic for these strains ranged from 10 to 800 mug/ml. Two strains sensitive to 20 mug of chlorhexidine/ml were adapted to resistance by growth i...

journal_title：Journal of clinical pathology

authors： Stickler DJ

更新日期：1974-04-01 00:00:00

abstract：AIMS:To assess A103 (melan-A) immunoreactivity in a range of ovarian sex cord stromal tumours and to evaluate it for the differential diagnosis of other neoplasms. METHODS:Paraffin embedded tissue sections from 45 sex cord stromal tumours and 44 potential histological mimics were examined immunohistochemically using t...

journal_title：Journal of clinical pathology

authors： Stewart CJ,Nandini CL,Richmond JA

更新日期：2000-03-01 00:00:00

abstract：:The distribution of laminin, a basement membrane glycoprotein, was studied by an immunohistochemical technique in six samples of benign sclerosing lesions of extrahepatic bile ducts and in 11 sclerosing cholangiocarcinomas. The expression of laminin showed that benign glandular structures were surrounded by a mainly i...

journal_title：Journal of clinical pathology

authors： Haglund C,Roberts PJ,Nordling S

更新日期：1989-09-01 00:00:00