Identification of reactive intermediate formation and bioactivation pathways in Abemaciclib metabolism by LC-MS/MS: in vitro metabolic investigation.

abstract：:Soil detritivores such as Collembola impact plant growth, tissue nutrient concentration and gene expression. Using a model system with pedunculate oak (Quercus robur) microcuttings that display a typical endogenous rhythmic growth with alternating shoot (SF) and root flushes (RF), we investigated the transcriptomic re...

journal_title：Royal Society open science

authors： Graf M,Bönn M,Feldhahn L,Kurth F,Grams TEE,Herrmann S,Tarkka M,Buscot F,Scheu S

更新日期：2019-03-06 00:00:00

abstract：:A key challenge in the fabrication of ferromagnetically filled carbon nano-onions (CNOs) is the control of their thickness, dimensions and electric properties. Up to now literature works have mainly focused on the encapsulation of different types of ferromagnetic materials including α-Fe, Fe3C, Co, FeCo, FePd3 and oth...

journal_title：Royal Society open science

authors： Medranda D,Borowiec J,Zhang X,Wang S,Yan K,Zhang J,He Y,Ivaturi S,Boi FS

更新日期：2018-01-17 00:00:00

abstract：:The constraint release (CR) mechanism has important effects on polymer relaxation and the chains will show different relaxation behaviour in conditions of monodisperse, bidisperse and other topological environments. By comparing relaxation data of linear polyisoprene (PI) chains dissolved in very long matrix and monod...

journal_title：Royal Society open science

authors： Ma T,Lin G,Tan H

更新日期：2020-03-18 00:00:00

abstract：:Digested sludge, as the main by-product of the sewage sludge anaerobic digestion process, still contains considerable organic compounds. In this protocol, we report a facile method for preparing digested sludge-derived self-doped porous carbon material for high-performance supercapacitor electrodes via a sustainable p...

journal_title：Royal Society open science

authors： Zhang JJ,Fan HX,Dai XH,Yuan SJ

更新日期：2018-04-11 00:00:00

abstract：:Selten's game is a kidnapping model where the probability of capturing the kidnapper is independent of whether the hostage has been released or executed. Most often, in view of the elevated sensitivities involved, authorities put greater effort and resources into capturing the kidnapper if the hostage has been execute...

journal_title：Royal Society open science

authors： Iqbal A,Masson V,Abbott D

更新日期：2017-12-06 00:00:00

abstract：:Highwall mining (HWM) technology is an efficient method for exploiting residual coal resources in Chinese open-pit coal mines. However, on-site personnel and equipment can be damaged by the instability of the highwall mining residual coal pillars and subsidence of final end-walls. This paper considers the geological c...

journal_title：Royal Society open science

authors： Wang F,Zhang C

更新日期：2019-04-03 00:00:00

abstract：:Recent advances in biotechnology led to generation of large complex biological and clinical datasets that can be used to infer the underlying mechanism of many diseases and arrive at personalized treatments. One of these datasets are the whole genome profiles, including a good collection of publicly available human ge...

journal_title：Royal Society open science

authors： Su S,Shahriyari L

更新日期：2020-04-29 00:00:00

abstract：:When addressing their young infants, parents systematically modify their speech. Such infant-directed speech (IDS) contains exaggerated vowel formants, which have been proposed to foster language development via articulation of more distinct speech sounds. Here, this assumption is rigorously tested using both acoustic...

journal_title：Royal Society open science

authors： Kalashnikova M,Carignan C,Burnham D

更新日期：2017-08-02 00:00:00

abstract：:Quantum computers are expected to have a dramatic impact on numerous fields due to their anticipated ability to solve classes of mathematical problems much more efficiently than their classical counterparts. This particularly applies to domains involving integer factorization and discrete logarithms, such as public ke...

journal_title：Royal Society open science

authors： Stewart I,Ilie D,Zamyatin A,Werner S,Torshizi MF,Knottenbelt WJ

更新日期：2018-06-20 00:00:00

abstract：:The settlement of reef-building corals is critical to the survival and recovery of reefs. Recent evidence indicates that coral larvae orient towards reef sound, yet the components of the acoustic environment that may attract coral larvae and induce settlement are unknown. Here we investigated the effects of ambient so...

journal_title：Royal Society open science

authors： Lillis A,Apprill A,Suca JJ,Becker C,Llopiz JK,Mooney TA

更新日期：2018-12-12 00:00:00

abstract：:An efficient, high-yield and rapid synthesis of (E)-1,5-dimethyl-4-((2-((substituted-2-oxo-2H-chromen-4-yl)methoxy)naphthalen-1-yl)methyleneamino)-2-phenyl-1,2-dihydropyrazol-3-one derivatives (3a-3i) containing Schiff base structures under microwave-irradiation has been described. Schiff base is a potential target to...

journal_title：Royal Society open science

authors： Chavan RR,Hosamani KM

更新日期：2018-05-02 00:00:00

abstract：:In the centuries since the enlightenment, the world has seen an increase in socioeconomic development, measured as increased life expectancy, education, economic development and democracy. While the co-occurrence of these features among nations is well documented, little is known about their origins or co-evolution. H...

journal_title：Royal Society open science

authors： Ruck DJ,Bentley RA,Lawson DJ

更新日期：2020-02-12 00:00:00

abstract：:In plants, plant fructokinases (FRKs) are considered to be the main gateway of fructose metabolism as they can phosphorylate fructose to fructose-6-phosphate. Chinese white pears (Pyrus bretschneideri) are one of the popular fruits in the world market; sugar content is an important factor affecting the quality of the ...

journal_title：Royal Society open science

authors： Cao Y,Li S,Han Y,Meng D,Jiao C,Abdullah M,Li D,Jin Q,Lin Y,Cai Y

更新日期：2018-07-18 00:00:00

abstract：:Zeolitic-imidazole frameworks (ZIFs), as novel porous materials, are attracting much attention in several fields due to their special advantages such as large specific surface area, versatile porosity and well-connected networks. Here, we develop a porous ZIF-derived catalytic thin film, which was coated on the conduc...

journal_title：Royal Society open science

authors： Xu W,Sun Y,Ding B,Zhang J

更新日期：2018-05-30 00:00:00

abstract：:The Internet not only has changed the dynamics of our collective attention but also through the transactional log of online activities, provides us with the opportunity to study attention dynamics at scale. In this paper, we particularly study attention to aircraft incidents and accidents using Wikipedia transactional...

journal_title：Royal Society open science

authors： García-Gavilanes R,Tsvetkova M,Yasseri T

更新日期：2016-10-12 00:00:00

abstract：:In this study, photocatalytic experiments of 20 mg l-1 sulfamethazine (SMN) in aqueous solution containing ZnO with different morphologies, tetra-needle-like ZnO (T-ZnO), flower-like ZnO (F-ZnO) and nanoparticles ZnO (P-ZnO), were performed. The results indicated that photocatalytic degradation of SMN was effective an...

journal_title：Royal Society open science

authors： Yi Z,Wang J,Jiang T,Tang Q,Cheng Y

更新日期：2018-04-11 00:00:00

abstract：:We present experimental data on the nematic alignment of Escherichia coli bacteria confined in a slit, with an emphasis on the effect of growth rate and corresponding changes in cell aspect ratio. Global alignment with the channel walls arises from the combination of local nematic ordering of nearby cells, induced by ...

journal_title：Royal Society open science

authors： Sheats J,Sclavi B,Cosentino Lagomarsino M,Cicuta P,Dorfman KD

更新日期：2017-06-21 00:00:00

abstract：:Avoiding biological contaminants is a well-known manifestation of the adaptive system of disgust. In theory, animals evolved with such a system to prevent pathogen and parasite infection. Bodily products are human-universal disgust elicitors, but whether they also elicit avoidance behaviour in non-human primates has y...

journal_title：Royal Society open science

authors： Sarabian C,Ngoubangoye B,MacIntosh AJJ

更新日期：2017-11-08 00:00:00

abstract：:Racing pigeons are exposed to and act as carriers of diseases. Dietary protein requirement for their maintenance has not been determined experimentally despite their being domesticated for over 7000 years. A maintenance nitrogen (protein) requirement (MNR) for pigeons was determined in a balance study using diets cont...

journal_title：Royal Society open science

authors： Mabuchi Y,Frankel TL

更新日期：2016-03-23 00:00:00

abstract：:Robust imaging techniques for tracking insects have been essential tools in numerous laboratory and field studies on pests, beneficial insects and model systems. Recent innovations in optical imaging systems and associated signal processing have enabled detailed characterization of nocturnal mosquito behaviour around ...

journal_title：Royal Society open science

authors： Voloshin V,Kröner C,Seniya C,Murray GPD,Guy A,Towers CE,McCall PJ,Towers DP

更新日期：2020-05-13 00:00:00

abstract：:Wheat farming provides 28.5% of global cereal production. After steady growth in average crop yield from 1950 to 1990, wheat yields have generally stagnated, which prompts the question of whether further improvements are possible. Statistical studies of agronomic parameters such as crop yield have so far exclusively f...

journal_title：Royal Society open science

authors： Mitchell EG,Crout NMJ,Wilson P,Wood ATA,Stupfler G

更新日期：2020-04-22 00:00:00

abstract：:Comprehensive diagnosis of polychlorinated dibenzo-p-dioxin and dibenzofuran (PCDD/F) emissions was systematically conducted on three hazardous waste incinerators (HWIs). Results indicated that PCDD/F mainly existed in the solid phase before the bag filter. This was especially true for higher chlorinated dioxin and fu...

journal_title：Royal Society open science

authors： Cao X,Ji L,Lin X,Stevens WR,Tang M,Shang F,Tang S,Lu S

更新日期：2018-07-11 00:00:00

abstract：:The present study introduces thermogravimetry with gas chromatography-mass spectrometry (TG-GC-MS) at four different heating rates to investigate the activation energy and thermal degradation behaviour of walnut shell pyrolysis. The distributed activation energy model (DAEM) was applied to investigate the activation e...

journal_title：Royal Society open science

authors： Fan F,Li H,Xu Y,Liu Y,Zheng Z,Kan H

更新日期：2018-09-12 00:00:00

abstract：:This study describes the 35-year progression of activities in the Pontal do Paranapanema region of São Paulo State, Brazil. These activities began as a research project on the conservation ecology of the highly endangered Black Lion Tamarin and broadened into a landscape-scale restoration and conservation project invo...

journal_title：Royal Society open science

authors： Chazdon RL,Cullen L Jr,Padua SM,Padua CV

更新日期：2020-12-09 00:00:00

abstract：:Pseudohyphal growth of the dimorphic yeast Saccharomyces cerevisiae is analysed using two-dimensional top-down binary images. The colony morphology is characterized using clustered shape primitives (CSPs), which are learned automatically from the data and thus do not require a list of predefined features or a priori k...

journal_title：Royal Society open science

authors： Gontar A,Bottema MJ,Binder BJ,Tronnolone H

更新日期：2018-10-17 00:00:00

abstract：:Nanofertilization is postulated as a new technology to deal with the environmental problems caused by the intensive use of traditional fertilizers. One of the aims of this new technology is to improve foliar fertilization, which has many environmental advantages, but currently there are numerous factors that limit its...

journal_title：Royal Society open science

authors： Rios JJ,Yepes-Molina L,Martinez-Alonso A,Carvajal M

更新日期：2020-11-04 00:00:00

abstract：:Chronic graft-versus-host disease (cGVHD) is a severe complication of allogeneic haematopoietic stem cell transplantation. There is a growing understanding of cGVHD, and several effective therapies for cGVHD have been reported. However, pancreatic cGVHD is a potentially untapped study field. Our thought-provoking stud...

journal_title：Royal Society open science

authors： Mukai S,Ogawa Y,Urano F,Kawakami Y,Tsubota K

更新日期：2018-10-17 00:00:00

abstract：:Nano-size EVONIK AEROXIDE® P25 titanium dioxide, TiO2, powder was heat-treated at temperatures, 700-900°C, in air. An X-ray diffraction study showed that the P25 powder is composed of approximately 20 and approximately 80 mass% of rutile and anatase phases, respectively. It was also shown that the transformation from ...

journal_title：Royal Society open science

authors： Ishigaki T,Nakada Y,Tarutani N,Uchikoshi T,Tsujimoto Y,Isobe M,Ogata H,Zhang C,Hao D

更新日期：2020-01-15 00:00:00

abstract：:Frugal products possess a proper mix of features including minimal consumption of resources, good functionality under nominal conditions and low cost. Therefore, increasing use of frugal products, that are designed and also fabricated systematically, is crucial to all-round sustainable development. However, their low ...

journal_title：Royal Society open science

authors： Rao BC

更新日期：2020-07-08 00:00:00

abstract：:[This corrects the article DOI: 10.1098/rsos.181295.]. ...

journal_title：Royal Society open science

authors： Hansford JP,Turvey ST

更新日期：2020-09-16 00:00:00