Metabolic Engineering for Improved Fermentation of L-Arabinose.

Abstract:

:L-Arabinose, a five carbon sugar, has not been considered as an important bioresource because most studies have focused on D-xylose, another type of five-carbon sugar that is prevalent as a monomeric structure of hemicellulose. In fact, L-arabinose is also an important monomer of hemicellulose, but its content is much more significant in pectin (3-22%, g/g pectin), which is considered an alternative biomass due to its low lignin content and mass production as juiceprocessing waste. This review presents native and engineered microorganisms that can ferment L-arabinose. Saccharomyces cerevisiae is highlighted as the most preferred engineering host for expressing a heterologous arabinose pathway for producing ethanol. Because metabolic engineering efforts have been limited so far, with this review as momentum, more attention to research is needed on the fermentation of L-arabinose as well as the utilization of pectin-rich biomass.

journal_name

J Microbiol Biotechnol

authors

Ye S,Kim JW,Kim SR

doi

10.4014/jmb.1812.12015

subject

Has Abstract

pub_date

2019-03-28 00:00:00

pages

339-346

issue

3

eissn

1017-7825

issn

1738-8872

pii

10.4014/jmb.1812.12015

journal_volume

29

pub_type

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