Integrative omics analysis in Pandanus odorifer (Forssk.) Kuntze reveals the role of Asparagine synthetase in salinity tolerance.

abstract：:The P2X receptor family of ATP-gated cation channels are attractive drug targets for pain and inflammatory disease, but no subtype-selective agonists, and few partially selective agonists have been described to date. As proof-of-concept for the discovery of novel P2X receptor agonists, here we demonstrate the use of D...

journal_title：Scientific reports

authors： Grimes L,Griffiths J,Pasqualetto G,Brancale A,Kemp PJ,Young MT,van der Goes van Naters W

更新日期：2020-05-19 00:00:00

abstract：:This study describes a new two-step process to cool the thermal vibration of microcantilevers. The process combines active mechanical feedback cooling and optical cavity cooling. A micro-Fabry-Perot interferometer, built in-house, is set atop a microcantilever to measure the vibration amplitude, the high optical power...

journal_title：Scientific reports

authors： Kawamura Y

更新日期：2019-12-13 00:00:00

abstract：:Based on the electrical characteristic detection technology, the quantitative prediction models of sensory score and physical and chemical quality Index (theaflavins, thearubigins, and theabrownins) were established by using the fermented products of Congou black tea as the research object. The variation law of electr...

journal_title：Scientific reports

authors： Dong C,An T,Zhu H,Wang J,Hu B,Jiang Y,Yang Y,Li J

更新日期：2020-01-31 00:00:00

abstract：:This study aims to investigate the relation between vaginal microbiota and exposition to intra-amniotic inflammation (IAI). We conducted a prospective cohort study in women with preterm labor <34 weeks who had undergone amniocentesis to rule out IAI. Vaginal samples were collected after amniocentesis. Women with IAI i...

journal_title：Scientific reports

authors： Cobo T,Vergara A,Collado MC,Casals-Pascual C,Herreros E,Bosch J,Sánchez-García AB,López-Parellada R,Ponce J,Gratacós E

更新日期：2019-12-12 00:00:00

abstract：:Plant litter is an important component in wetland ecosystems, and the role of plant litter decomposition is considered to be important for wetland ecosystem functions and services. However, the consequences of litter inputs have seldom been experimentally tested in real ecosystems such as constructed wetlands (CWs). T...

journal_title：Scientific reports

authors： Ping Y,Pan X,Li W,Wang J,Cui L

更新日期：2019-09-25 00:00:00

abstract：:Soft ferromagnetic Fe-based bulk metallic glass key-shaped specimens with a maximum and minimum width of 25.4 and 5 mm, respectively, were successfully produced using a high pressure die casting (HPDC) method, The influence of die material, alloy temperature and flow rate on the microstructure, thermal stability and s...

journal_title：Scientific reports

authors： Ramasamy P,Szabo A,Borzel S,Eckert J,Stoica M,Bárdos A

更新日期：2016-10-11 00:00:00

abstract：:Although a slowing of electroencephalographic (EEG) activity during wakefulness and -to some extent- sleep of Alzheimer disease (AD) patients (i.e., increased slow-frequency activity) was documented, recent findings in healthy elderly show a decreased 0.6-1 Hz slow wave activity (SWA) during NREM, which was associated...

journal_title：Scientific reports

authors： De Gennaro L,Gorgoni M,Reda F,Lauri G,Truglia I,Cordone S,Scarpelli S,Mangiaruga A,D'atri A,Lacidogna G,Ferrara M,Marra C,Rossini PM

更新日期：2017-01-03 00:00:00

abstract：:Dairy cows are often fed a high-concentrate (HC) diet to meet lactation demands; however, long-term concentrate feeding is unhealthy and decreases milk fat. Therefore, we investigated the effects of liver lipid metabolism on milk fat synthesis. Ten lactating Holstein cows were assigned randomly into HC and LC (low-con...

journal_title：Scientific reports

authors： Li L,Cao Y,Xie Z,Zhang Y

更新日期：2017-03-13 00:00:00

abstract：:Primary Sjögren's syndrome (pSS) is a complex autoimmune disease characterized by dysfunction of secretory epithelia with only palliative therapy. Patients present with a constellation of symptoms, and the diversity of symptomatic presentation has made it difficult to understand the underlying disease mechanisms. In t...

journal_title：Scientific reports

authors： Tanaka T,Warner BM,Odani T,Ji Y,Mo YQ,Nakamura H,Jang SI,Yin H,Michael DG,Hirata N,Suizu F,Ishigaki S,Oliveira FR,Motta ACF,Ribeiro-Silva A,Rocha EM,Atsumi T,Noguchi M,Chiorini JA

更新日期：2020-09-16 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Robertson KE,Truong CD,Craciunescu FM,Yang JH,Chiu PL,Fromme P,Hansen DT

更新日期：2020-03-02 00:00:00

abstract：:The β5 subunit of the proteasome has been shown in worms and in human cell lines to be regulatory. In these models, β5 overexpression results in upregulation of the entire proteasome complex which is sufficient to increase proteotoxic stress resistance, improve metabolic parameters, and increase longevity. However, fu...

journal_title：Scientific reports

authors： Nguyen NN,Rana A,Goldman C,Moore R,Tai J,Hong Y,Shen J,Walker DW,Hur JH

更新日期：2019-02-28 00:00:00

abstract：:Hirsutella sinensis mycelium (HSM), the anamorph of Cordyceps sinensis, is a traditional Chinese medicine that has been shown to possess various pharmacological properties. We previously reported that this fungus suppresses interleukin-1β and IL-18 secretion by inhibiting both canonical and non-canonical inflammasomes...

journal_title：Scientific reports

authors： Huang TT,Lai HC,Ko YF,Ojcius DM,Lan YW,Martel J,Young JD,Chong KY

更新日期：2015-10-26 00:00:00

abstract：:Prolonged healing and scar formation are two major challenges in the treatment of soft tissue trauma. Adipose mesenchymal stem cells (ASCs) play an important role in tissue regeneration, and recent studies have suggested that exosomes secreted by stem cells may contribute to paracrine signaling. In this study, we inve...

journal_title：Scientific reports

authors： Hu L,Wang J,Zhou X,Xiong Z,Zhao J,Yu R,Huang F,Zhang H,Chen L

更新日期：2016-09-12 00:00:00

abstract：:Present study, for the first time, reports the development of a nanohybridized baculovirus based stent that can locally promote vascular re-endothelialization by efficient delivery of pro-angiogenic vascular endothelial growth factor (Vegf) genes. In vitro data demonstrated rapid expression of functionally active Vegf...

journal_title：Scientific reports

authors： Paul A,Elias CB,Shum-Tim D,Prakash S

更新日期：2013-01-01 00:00:00

abstract：:In this work, we show that it is possible to overcome the limitations of solid-state MRI for rigid tissues due to large line broadening and short dephasing times by combining Magic Angle Spinning (MAS) with rotating pulsed field gradients. This allows recording ex vivo 31P 3D and 2D slice-selected images of rigid tiss...

journal_title：Scientific reports

authors： Yon M,Sarou-Kanian V,Scheler U,Bouler JM,Bujoli B,Massiot D,Fayon F

更新日期：2017-08-15 00:00:00

abstract：:New plant protection strategies focus on minimizing chemical pesticide use and increasing their compatibility with biological control agents. The objective was to evaluate the side-effects of glyphosate, diflubenzuron, malathion, tebuconazole and triflumuron (at 720, 45, 400, 150 and 20 g ai ha-1, respectively), pesti...

journal_title：Scientific reports

authors： Cruz RA,Zanuncio JC,Lacerda MC,Wilcken CF,Fernandes FL,Tavares WS,Soares MA,Sediyama CS

更新日期：2017-08-30 00:00:00

abstract：:Generation of multiple mRNAs by alternative splicing is well known in the group of cytokines and has recently been reported for the human erythropoietin (EPO) gene. Here, we focus on the alternatively spliced EPO transcript characterized by deletion of exon 3 (hEPOΔ3). We show co-regulation of EPO and hEPOΔ3 in human ...

journal_title：Scientific reports

authors： Bonnas C,Wüstefeld L,Winkler D,Kronstein-Wiedemann R,Dere E,Specht K,Boxberg M,Tonn T,Ehrenreich H,Stadler H,Sillaber I

更新日期：2017-06-16 00:00:00

abstract：:Desmoid tumors (aggressive fibromatosis) are locally invasive soft tissue tumors that lack the ability to metastasize. There are no directed therapies or standard treatment plan, and chemotherapeutics, radiation, and surgery often have temporary effects. The majority of desmoid tumors are related to T41A and S45F muta...

journal_title：Scientific reports

authors： Mercier KA,Al-Jazrawe M,Poon R,Acuff Z,Alman B

更新日期：2018-01-12 00:00:00

abstract：:We recently reported that R-spondin 2 (Rspo2), a secreted activator of Wnt/β-catenin signaling, promotes acetylcholine receptor (AChR) clustering and neuromuscular junction (NMJ) formation via its receptor, Lgr5. Rspo2 is expressed highly in spinal motor neurons (SMNs) and marginally in the skeletal muscle, but the or...

journal_title：Scientific reports

authors： Li J,Ito M,Ohkawara B,Masuda A,Ohno K

更新日期：2018-09-11 00:00:00

abstract：:We present a new method for the design of devices to manipulate the displacement field in Elastic materials. It consists of solving a nonlinear optimization problem where the objective function defines the error in matching a desired displacement field, and the design variables determine the required material distribu...

journal_title：Scientific reports

authors： Fachinotti VD,Peralta I,Albanesi AE

更新日期：2018-06-29 00:00:00

abstract：:Several studies have shown that the 'poor' sperm DNA quality appears to be an important factor affecting male reproductive ability. In the case of sperm cells from males with the correct somatic karyotype but with deficient spermatogenesis, resulting in a high degree of sperm DNA fragmentation, we observed changes in ...

journal_title：Scientific reports

authors： Wiland E,Fraczek M,Olszewska M,Kurpisz M

更新日期：2016-08-25 00:00:00

abstract：:Chronic wounds affect millions of patients around the world and their treatment is challenging as the early signs indicating their development are subtle. In addition, a type of chronic wound, known as pressure ulcer, develops in patients with limited mobility. Infection and frequent bleeding are indicators of chronic...

journal_title：Scientific reports

authors： Farooqui MF,Shamim A

更新日期：2016-06-29 00:00:00

abstract：:This retrospective cohort study examined the relationship between a cholecystectomy and the subsequent risk of peptic ulcers using a population-based database. Data for this study were retrieved from the Taiwan Longitudinal Health Insurance Database 2005. This study included 5209 patients who had undergone a cholecyst...

journal_title：Scientific reports

authors： Tsai MC,Huang CC,Kao LT,Lin HC,Lee CZ

更新日期：2016-07-29 00:00:00

abstract：:Allosteric modulation of G protein-coupled receptors represent a promising mechanism of pharmacological intervention. Dramatic developments witnessed in the structural biology of membrane proteins continue to reveal that the binding sites of allosteric modulators are widely distributed, including along protein surface...

journal_title：Scientific reports

authors： Wakefield AE,Mason JS,Vajda S,Keserű GM

更新日期：2019-04-16 00:00:00

abstract：:Climate-driven environmental change and land-use change often interact in their impact on biodiversity, but these interactions have received little scientific attention. Here we study the effects of climate-driven environmental variation (i.e. vegetation greenness) and land-use (protected versus unprotected areas) on ...

journal_title：Scientific reports

authors： Santangeli A,Spiegel O,Bridgeford P,Girardello M

更新日期：2018-08-29 00:00:00

abstract：:We introduce a new chemical space for drugs and drug-like molecules, exclusively based on their in silico ADME behaviour. This ADME-Space is based on self-organizing map (SOM) applied to 26,000 molecules. Twenty accurate QSPR models, describing important ADME properties, were developed and, successively, used as new m...

journal_title：Scientific reports

authors： Bocci G,Carosati E,Vayer P,Arrault A,Lozano S,Cruciani G

更新日期：2017-07-25 00:00:00

abstract：:Empirical yield estimation from satellite data has long lacked suitable combinations of spatial and temporal resolutions. Consequently, the selection of metrics, i.e., temporal descriptors that predict grain yield, has likely been driven by practicality and data availability rather than by systematic targetting of cri...

journal_title：Scientific reports

authors： Waldner F,Horan H,Chen Y,Hochman Z

更新日期：2019-10-31 00:00:00

abstract：:Advances in single-photon sources (SPSs) and single-photon detectors (SPDs) promise unique applications in the field of quantum information technology. In this paper, we report long-distance quantum key distribution (QKD) by using state-of-the-art devices: a quantum-dot SPS (QD SPS) emitting a photon in the telecom ba...

journal_title：Scientific reports

authors： Takemoto K,Nambu Y,Miyazawa T,Sakuma Y,Yamamoto T,Yorozu S,Arakawa Y

更新日期：2015-09-25 00:00:00

abstract：:River ecosystem health assessments provide the foundation for river ecological protection and integrated management. To evaluate the aquatic ecosystem health of the Fan River basin, benthic macroinvertebrate indices (the Multimeric Macroinvertebrates Index Flanders (MMIF) and Family Biotic Index (FBI)), a habitat inde...

journal_title：Scientific reports

authors： Chen J,Wang Y,Li F,Liu Z

更新日期：2019-10-01 00:00:00

abstract：:Elastic waves are guided along finite structures such as cylinders, plates, or rods through reflection, refraction, and mode conversion at the interfaces. Such wave propagation is ubiquitous in the world around us, and studies of elastic waveguides first emerged in the later part of the 19(th) century. Early work on e...

journal_title：Scientific reports

authors： Philippe FD,Murray TW,Prada C

更新日期：2015-06-08 00:00:00