A framework for the ethical assessment of chimeric animal research involving human neural tissue.

abstract：BACKGROUND:Surgery for intersex infants should be delayed until individuals are able to decide for themselves, except where it is a medical necessity. In an ideal world, this single principle would suffice and such surgeries could be totally prohibited. Unfortunately, the world is not perfect, and, in some places, inte...

journal_title：BMC medical ethics

authors： Behrens KG

更新日期：2020-10-29 00:00:00

abstract：BACKGROUND:It is widely acknowledged that there is a global divide on health care and health research known as the 10/90 divide. METHODS:A retrospective survey of articles published in the BMJ, Lancet, NEJM, Annals of Internal Medicine & JAMA in a calendar year to examine the contribution of the developing world to me...

journal_title：BMC medical ethics

authors： Sumathipala A,Siribaddana S,Patel V

更新日期：2004-10-04 00:00:00

abstract：BACKGROUND:In August 2017, Chile lifted its complete ban on abortion by permitting abortion in three limited circumstances: 1) to save a woman's life, 2) lethal fetal anomaly, and 3) rape. The new law allows regulated use of conscientious objection (CO) in abortion care, including allowing institutions to register as o...

journal_title：BMC medical ethics

authors： Biggs MA,Casas L,Ramm A,Baba CF,Correa SP

更新日期：2020-05-24 00:00:00

abstract：BACKGROUND:Cancer patients are at risk of developing blood clots in their veins - venous thromboembolism (VTE) - which often takes the form of a pulmonary embolism or deep vein thrombosis. The risk increases with advanced disease. Evidence based treatment is low molecular weight heparin (LMWH) by daily subcutaneous inj...

journal_title：BMC medical ethics

authors： Sheard L,Prout H,Dowding D,Noble S,Watt I,Maraveyas A,Johnson M

更新日期：2012-09-04 00:00:00

abstract：BACKGROUND:Mobile applications and socio-sexual networking websites are used by outreach workers to respond synchronously to questions and provide information, resources, and referrals on sexual health and STI/HIV prevention, testing, and care to gay, bisexual and other men who have sex with men (GB2M). This explorator...

journal_title：BMC medical ethics

authors： Fantus S,Souleymanov R,Lachowsky NJ,Brennan DJ

更新日期：2017-11-03 00:00:00

abstract：BACKGROUND:Although informed consent is an integral part of clinical practice, its current doctrine remains mostly a matter of law and mainstream ethics rather than empirical research. There are scarce empirical data on patients' perceived purpose of informed consent, which may include administrative routine/courtesy g...

journal_title：BMC medical ethics

authors： Hammami MM,Al-Gaai EA,Al-Jawarneh Y,Amer H,Hammami MB,Eissa A,Qadire MA

更新日期：2014-01-10 00:00:00

abstract：BACKGROUND:HIV prevention research in resource-limited countries is associated with a variety of ethical dilemmas. Key amongst these is the question of what constitutes an appropriate standard of health care (SoC) for participants in HIV prevention trials. This paper describes a community-focused approach to develop a ...

journal_title：BMC medical ethics

authors： Vallely A,Shagi C,Lees S,Shapiro K,Masanja J,Nikolau L,Kazimoto J,Soteli S,Moffat C,Changalucha J,McCormack S,Hayes RJ

更新日期：2009-10-09 00:00:00

abstract：BACKGROUND:Precision medicine (PM) is an emerging approach to individualized care. It aims to help physicians better comprehend and predict the needs of their patients while effectively adopting in a timely manner the most suitable treatment by promoting the sharing of health data and the implementation of learning hea...

journal_title：BMC medical ethics

authors： Geneviève LD,Martani A,Shaw D,Elger BS,Wangmo T

更新日期：2020-02-19 00:00:00

abstract：BACKGROUND:Plagiarism is considered as serious research misconduct, together with data fabrication and falsification. However, little is known about biomedical researchers' views on plagiarism. Moreover, it has been argued - based on limited empirical evidence - that perceptions of plagiarism depend on cultural and oth...

journal_title：BMC medical ethics

authors： Yi N,Nemery B,Dierickx K

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Despite the growing recognition for the need to improve the health of prisoners in Canada and the need for health research, there has been little discussion of the ethical issues with regards to health research with prisoners in Canada. The purpose of this paper is to encourage a national conversation about ...

journal_title：BMC medical ethics

authors： Silva DS,Matheson FI,Lavery JV

更新日期：2017-04-27 00:00:00

abstract：BACKGROUND:Several charters of rights have been issued in Europe to solemnly proclaim the rights of children during their hospital stay. However, notwithstanding such general declarations, the actual implementation of hospitalized children's rights is unclear. The purpose of this study was to understand to which extent...

journal_title：BMC medical ethics

authors： Bisogni S,Aringhieri C,McGreevy K,Olivini N,Lopez JR,Ciofi D,Merlo AM,Mariotti P,Festini F

更新日期：2015-05-13 00:00:00

abstract：BACKGROUND:Various forms of Clinical Ethics Support (CES) have been developed in health care organizations. Over the past years, increasing attention has been paid to the question of how to foster the quality of ethics support. In the Netherlands, a CES quality assessment project based on a responsive evaluation design...

journal_title：BMC medical ethics

authors： Van Baarle EM,Potma MC,van Hoek MEC,Hartman LA,Molewijk BAC,van Gurp JLP

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Patient outcome after serious brain injury is highly variable. Following a period of coma, some patients recover while others progress into a vegetative state (unresponsive wakefulness syndrome) or minimally conscious state. In both cases, assessment is difficult and misdiagnosis may be as high as 43%. Recen...

journal_title：BMC medical ethics

authors： Weijer C,Peterson A,Webster F,Graham M,Cruse D,Fernández-Espejo D,Gofton T,Gonzalez-Lara LE,Lazosky A,Naci L,Norton L,Speechley K,Young B,Owen AM

更新日期：2014-05-20 00:00:00

abstract：BACKGROUND:Few studies have examined factors associated with willingness of people living with HIV (PLHIV) to participate in HIV treatment clinical trials in Sub-Saharan Africa. We assessed the factors associated with participation of PLHIV in HIV treatment clinical trials research at a large urban clinical and researc...

journal_title：BMC medical ethics

authors： Sebatta DE,Siu G,Nabeta HW,Anguzu G,Walimbwa S,Lamorde M,Bukenya B,Kambugu A

更新日期：2020-08-24 00:00:00

abstract：BACKGROUND:Expectations of receiving personal health information as a fringe benefit of biospecimen donation-termed diagnostic misconception-are increasingly documented. We developed an instrument measuring conflation of observational biospecimen-based research and clinical care for use with Latino communities, who may...

journal_title：BMC medical ethics

authors： Knerr S,Ceballos RM

更新日期：2015-07-17 00:00:00

abstract：BACKGROUND:Evidence concerning how Japanese physicians think and behave in specific clinical situations that involve withholding or withdrawal of medical interventions for end-of-life or frail elderly patients is yet insufficient. METHODS:To analyze decisions and actions concerning the withholding/withdrawal of life-s...

journal_title：BMC medical ethics

authors： Bito S,Asai A

更新日期：2007-06-19 00:00:00

abstract：BACKGROUND:Intensive care physicians often must rely on substitute decision makers to address all dimensions of the construct of "best interest" for incapable, critically ill patients. This task involves identifying prior wishes and to facilitate the substitute decision maker's understanding of the incapable patient's ...

journal_title：BMC medical ethics

authors： Ratnapalan M,Cooper AB,Scales DC,Pinto R

更新日期：2010-02-10 00:00:00

abstract：BACKGROUND:We analyzed the patients' perception of prenatal diagnosis of fetal cardiac pathology, and the reasons for choosing to continue with pregnancy despite being eligible to receive a medical termination of pregnancy. We also identified the challenges, the motives interfering in decision-making, and the consequen...

journal_title：BMC medical ethics

authors： Abi Tayeh G,Jouannic JM,Mansour F,Kesrouani A,Attieh E

更新日期：2018-05-02 00:00:00

abstract：BACKGROUND:Family members are often required to act as substitute decision-makers when health care or research participation decisions must be made for an incapacitated relative. Yet most families are unable to accurately predict older adult preferences regarding future health care and willingness to engage in research...

journal_title：BMC medical ethics

authors： Bravo G,Arcand M,Blanchette D,Boire-Lavigne AM,Dubois MF,Guay M,Hottin P,Lane J,Lauzon J,Bellemare S

更新日期：2012-01-05 00:00:00

abstract：BACKGROUND:This paper explores ethical concerns arising in healthcare integration. We argue that integration is necessary imperative for meeting contemporary and future healthcare challenges, a far stronger evidence base for the conditions of its effectiveness is required. In particular, given the increasing emphasis a...

journal_title：BMC medical ethics

authors： McKeown A,Cliffe C,Arora A,Griffin A

更新日期：2019-07-03 00:00:00

abstract：BACKGROUND:Between 2013 and 2016, West Africa experienced the largest ever outbreak of Ebola Virus Disease. In the absence of registered treatments or vaccines to control this lethal disease, the World Health Organization coordinated and supported research to expedite identification of interventions that could control ...

journal_title：BMC medical ethics

authors： Alirol E,Kuesel AC,Guraiib MM,de la Fuente-Núñez V,Saxena A,Gomes MF

更新日期：2017-06-26 00:00:00

abstract：BACKGROUND:The ethical principle of justice demands that resources be distributed equally and based on evidence. Guidelines regarding forgoing of CPR are unavailable and there is large variance in the reported rates of attempted CPR in in-hospital cardiac arrest. The main objective of this work was to study whether loc...

journal_title：BMC medical ethics

authors： Ozer J,Alon G,Leykin D,Varon J,Aharonson-Daniel L,Einav S

更新日期：2019-12-26 00:00:00

abstract：BACKGROUND:The past 10 years have witnessed a significant growth in sharing of health data for secondary uses. Alongside this there has been growing interest in the public acceptability of data sharing and data linkage practices. Public acceptance is recognised as crucial for ensuring the legitimacy of current practice...

journal_title：BMC medical ethics

authors： Aitken M,de St Jorre J,Pagliari C,Jepson R,Cunningham-Burley S

更新日期：2016-11-10 00:00:00

abstract：BACKGROUND:Efforts to improve patients' understanding of their own medical treatments or research in which they are involved are progressing, especially with regard to informed consent procedures. We aimed to design a multisource informed consent procedure that is easily adaptable to both clinical and research applicat...

journal_title：BMC medical ethics

authors： Cervo S,Rovina J,Talamini R,Perin T,Canzonieri V,De Paoli P,Steffan A

更新日期：2013-07-30 00:00:00

abstract：BACKGROUND:Expanded access is the use of investigational drugs (IDs) outside of clinical trials. Generally it is performed in patients with serious and life-threatening diseases who cannot be treated satisfactorily with authorized drugs. Legal regulations of expanded access to IDs have been introduced among others in t...

journal_title：BMC medical ethics

authors： Borysowski J,Górski A

更新日期：2020-11-18 00:00:00

abstract：BACKGROUND:France has long been a country of immigration and in some respects may be seen to have a generous policy with respect to asylum seekers and access to health care for migrants. The French state notably provides healthcare access for undocumented migrants, through state medical aid and since 1998 has had a hum...

journal_title：BMC medical ethics

authors： Cailhol J,Lebon MC,Sherlaw W

更新日期：2020-07-13 00:00:00

abstract：BACKGROUND:Clinical Ethics Committees (CECs) are well established at healthcare institutions in resource-rich countries. However, there is limited information on established CECs in resource poor countries, especially in Africa. This study aimed to establish baseline data regarding existing formal CECs in Africa to rai...

journal_title：BMC medical ethics

authors： Moodley K,Kabanda SM,Soldaat L,Kleinsmidt A,Obasa AE,Kling S

更新日期：2020-11-18 00:00:00

abstract：BACKGROUND:Over the past 25 years, there has been growing recognition of the importance of studying the Ethical, Legal and Social Implications (ELSI) of genetic and genomic research. A large investment into ELSI research from the National Institutes of Health (NIH) Human Genomic Project budget in 1990 stimulated the gr...

journal_title：BMC medical ethics

authors： Bell J,Ancillotti M,Coathup V,Coy S,Rigter T,Tatum T,Grewal J,Akcesme FB,Brkić J,Causevic-Ramosevac A,Milovanovic G,Nobile M,Pavlidis C,Finlay T,Kaye J,ELSI2.0.

更新日期：2016-07-08 00:00:00

abstract：BACKGROUND:Since 2010, the European Journal of Anaesthesiology has required the reporting of five items concerning ethical approval in articles describing human research: ethics committee's name and address, chairperson's name, study's protocol number and approval date. We aimed to assess whether this requirement has h...

journal_title：BMC medical ethics

authors： Zoccatelli D,Tramèr MR,Elia N

更新日期：2018-06-08 00:00:00

abstract：BACKGROUND:With a growing number of genetic tests becoming available to the health and consumer markets, genetic health care providers in Canada are faced with the challenge of developing robust decision rules or guidelines to allocate a finite number of public resources. The objective of this study was to gain Canadia...

journal_title：BMC medical ethics

authors： Adair A,Hyde-Lay R,Einsiedel E,Caulfield T

更新日期：2009-06-18 00:00:00