Abstract:
AIM:Death as a result of pneumonia is an important issue in patients with diabetes. Tongue pressure is associated with swallowing function, which has a close association with aspiration pneumonia. However, no previous studies have shown the association between sarcopenia and tongue pressure in older patients with type 2 diabetes. METHODS:In the present cross-sectional study, we investigated body composition, handgrip strength and tongue pressure. Skeletal muscle mass index (kg/m2 ) was defined as appendicular muscle mass / the square of the height. Sarcopenia was defined when both handgrip strength <26 kg for men and <18 kg for women, and the skeletal muscle mass index <7.0 kg/m2 for men and <5.7 kg/m2 for women existed. RESULTS:Among 144 patients (82 men, 71.4 years [SD 6.7 years]), 11.8% had sarcopenia. Tongue pressure was associated with skeletal muscle mass index and handgrip strength (r = 0.361, P < 0.001 and r = 0.387, P < 0.001, respectively, in men; and r = 0.300, P = 0.018 and r = 0.538, P < 0.001, respectively, in women). Tongue pressure was associated with the prevalence of sarcopenia after adjusting for covariates (OR 3.83, 95% CI 1.06-13.9, P = 0.041). According to the receiver operating characteristic curve analysis, the optimal cut-off value of handgrip strength for the presence of low tongue pressure was 27.7 kg (AUC 0.70, 95% CI 0.53-0.83, sensitivity 0.78, specificity 0.64) in men and 18.3 kg (AUC 0.71, 95% CI 0.54-0.84, sensitivity 0.82, specificity 0.54) in women. CONCLUSIONS:Sarcopenia, especially handgrip strength, is associated with tongue pressure in older patients with type 2 diabetes. We should consider a decrease of swallowing function when examining patients with sarcopenia. Geriatr Gerontol Int 2019; 19: 153-158.
journal_name
Geriatr Gerontol Intjournal_title
Geriatrics & gerontology internationalauthors
Kaji A,Hashimoto Y,Kobayashi Y,Sakai R,Okamura T,Miki A,Hamaguchi M,Kuwahata M,Yamazaki M,Fukui Mdoi
10.1111/ggi.13577subject
Has Abstractpub_date
2019-02-01 00:00:00pages
153-158issue
2eissn
1444-1586issn
1447-0594journal_volume
19pub_type
杂志文章abstract:AIM:The aim of the present study was to examine whether behavioral and psychological symptoms of dementia at the time of admission could be a predictor of falls in older people with dementia residing in geriatric health service facilities. METHODS:Three geriatric health services facilities located in Fukushima Prefect...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.13528
更新日期:2018-11-01 00:00:00
abstract:AIM:To investigate the prevalence and burden (combination of number and severity) of vertebral fractures in men and women with hip fracture. METHODS:We investigated 458 of 490 hip-fracture patients admitted consecutively to a rehabilitation hospital. Lateral radiographs of the spine were taken 19.2 ± 5.5 days (mean ± ...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.12479
更新日期:2016-03-01 00:00:00
abstract:AIM:Acute gastrointestinal bleeding is a potentially life-threatening condition that requires rapid assessment and dynamic management. Several scoring systems are used to predict mortality and rebleeding in such cases. The aim of the present study was to compare three scoring systems for predicting short-term mortality...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.12757
更新日期:2017-04-01 00:00:00
abstract:AIM:To analyze the hierarchical structure of activities of daily living (ADL) among vestibular older adults, according to its power to discriminate disability. METHODS:An exploratory cross-sectional study was conducted comprising 235 elderly, aged 65 years and older, with chronic vestibular dysfunction. Functional cap...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/j.1447-0594.2010.00633.x
更新日期:2011-01-01 00:00:00
abstract:AIM:Single photon emission computed tomography (SPECT) studies showed that regional cerebral blood flow (rCBF) abnormalities in idiopathic rapid eye movement (REM) sleep behavior disorder (iRBD) are similar to those seen in Parkinson's disease (PD) and dementia with Lewy bodies (DLB). The aim of the present study was t...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.12068
更新日期:2014-01-01 00:00:00
abstract:AIM:Increases in oxidative stress and advanced glycation end-products (AGE) formation play an important role in the pathogenesis of aging. Carnosine (CAR; β-alanyl-L-histidine) has anti-oxidant and antiglycating properties. We investigated the effect of CAR supplementation on AGE levels, and protein and lipid oxidation...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.13126
更新日期:2017-12-01 00:00:00
abstract:AIM:Heredity plays an important role in the pathogenesis of Alzheimer's disease (AD) especially for single-nucleotide polymorphism (SNPs) of susceptible genes, which is one of the significant factors in the pathogenesis of AD. The SNPs of BIN1 rs744373, BIN1 rs7561528 and GAB2 rs2373115 are associated with AD in Asian ...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.14109
更新日期:2020-12-16 00:00:00
abstract:AIM:To determine whether elderly subjects with distinct histories of falls presented differences concerning the influence of sensory interaction on balance. METHODS:Cross-sectional research. Ninety-six community-dwelling elderly subjects were divided into three groups, according to the history of falls within the past...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/j.1447-0594.2009.00516.x
更新日期:2009-06-01 00:00:00
abstract::Glycosylation is the most common post-translational modification of proteins. Protein sequence data suggested that more than half of all proteins produced in mammalian cells are glycoproteins. Recent studies showed that glycans of secreted glycoproteins affect many protein properties, such as solubility, stability, pr...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章,评审
doi:10.1111/j.1447-0594.2010.00602.x
更新日期:2010-07-01 00:00:00
abstract:AIM:Depression affecting caregivers is a risk factor for discontinuing at-home care. The present cross-sectional study was conducted to evaluate factors related to depression among family caregivers. METHODS:A cross-sectional study was conducted to evaluate factors related to depression among family caregivers of the ...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/j.1447-0594.2011.00754.x
更新日期:2012-04-01 00:00:00
abstract:AIM:The angiotensin-converting enzyme gene (ACE) insertion (I)/deletion (D) polymorphism is considered a biologically plausible gene for Alzheimer's disease (AD) in cross-sectional studies. The present study aimed to investigate the longitudinal effect of ACE I/D polymorphism on AD progression. METHODS:This 3-year obs...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.12929
更新日期:2017-10-01 00:00:00
abstract:AIM:Aging shifts body composition to comprising more fat and less muscle. Sarcopenia, particularly in the knee extensors, and obesity, particularly visceral obesity, either alone or in combination, may exacerbate age-related physical disability. We investigated the association between age-related quadriceps (Qc) sarcop...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/j.1447-0594.2010.00610.x
更新日期:2010-07-01 00:00:00
abstract:AIMS:Inflammatory processes might play a significant role at the pathophysiology of Alzheimer's disease (AD). Neuroinflammation is characterized by activation of microglia and the release of inflammatory cytokines, such as interleukin (IL)-1β, IL-6 and tumor necrosis factor-α. Although, it is unknown what the real cont...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.12704
更新日期:2017-02-01 00:00:00
abstract:AIM:All consumer-directed care (CDC) models aim to transfer "choice" and "control" over the allocated funds from the aged care provider to service recipients. This study presents an empirical assessment of the relationships between quality of life for older adults aged ≥65 years receiving community aged care services i...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章,多中心研究
doi:10.1111/ggi.12872
更新日期:2017-10-01 00:00:00
abstract:AIM:The aim of the present study was to assess the relationship between neighborhood perception and poor self-rated health among older Mexican Americans, adjusting for important background characteristics, such as neighborhood ethnic composition and other health conditions. METHODS:Drawing on the 2004-2005 Hispanic Es...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.13089
更新日期:2017-12-01 00:00:00
abstract:AIM:Sarcopenia causes a decline in physical performance and decreased quality of life. However, there is little evidence for effective treatments. Because of the similarities between osteoporosis and sarcopenia, alfacalcidol used for osteoporosis might be beneficial for low muscle mass. Therefore, we investigated the e...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.12222
更新日期:2014-02-01 00:00:00
abstract:AIM:Alzheimer's disease (AD) is the most common neurodegenerative disease. In 2000, Mendiondo et al. reported on a model predicting that AD progresses at an accelerating rate and cognitive function worsens rapidly. Recently, anti-AD drugs and non-pharmacological intervention have been established, but the effect of int...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.13883
更新日期:2020-04-01 00:00:00
abstract:AIM:Our aim was to study the outcome and the predictors of in-hospital cardiopulmonary resuscitation (CPR) among elderly patients admitted to Ain Shams University Hospitals, Egypt. METHODS:We carried out a cross-sectional study for all elderly patients (age ≥60 years) who underwent CPR after cardiac arrest at Ain Sham...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章,收录出版
doi:10.1111/ggi.12099
更新日期:2014-04-01 00:00:00
abstract:AIM:The purpose of the present study was to investigate the injury types and medical utilization profiles of veterans in emergency department visits by using big data from the National Health Insurance program in Taiwan. METHOD:We used the outpatient prescriptions and treatment records between 1997 and 2010 of veteran...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.12620
更新日期:2016-12-01 00:00:00
abstract:AIM:To estimate the prevalence of diabetes, heart disease, hypertension and stroke in self-report and hospital data in two cohorts of women; measure sensitivity and agreement between data sources; and compare between cohorts. METHODS:Women born between 1946-1951 and 1921-1926 who participated in the Australian Longitu...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.12442
更新日期:2016-01-01 00:00:00
abstract:AIM:To clarify the factors associated with loss of independence multidimensionally over a 3-year period among community-dwelling older adults. METHODS:The survey was exclusively carried out by the local government for people aged >65 years who were independent at baseline living in H-City, a mid-sized urban city in Ja...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.13209
更新日期:2018-03-01 00:00:00
abstract:AIM:Calf circumference, which is a known simple indicator of muscle mass, increases during edema. However, the extent to which edema increases calf circumference in older adults is unclear. METHODS:This retrospective cross-sectional study included patients aged ≥65 years whose nutritional status was assessed by nutrit...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.13756
更新日期:2019-10-01 00:00:00
abstract:AIM:The present study investigated the status of potentially harmful drug-drug interactions (PHDI) in older adults, to obtain insight into factors that influence the risk of PHDI. METHODS:The present study included Korean people aged ≥65 years who were prescribed one or more drugs included in the list of PHDI under th...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.13495
更新日期:2018-09-01 00:00:00
abstract:AIM:The aim of the present study was to find out physicians' perceptions about the transfer of dying nursing home residents to emergency departments. METHOD:This qualitative study used semi-structured interviews, and data were analyzed using qualitative methods. Participants were medical directors of nursing homes who...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.13600
更新日期:2019-03-01 00:00:00
abstract:AIM:We studied the association between age and survival after stroke. We particularly focused on deaths that could be attributed to the stroke lesion itself; that is, early death in severe stroke. METHODS:A registry of all hospitalized stroke patients in Denmark included 93897 patients with information on stroke sever...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章,多中心研究
doi:10.1111/ggi.12165
更新日期:2014-10-01 00:00:00
abstract:AIM:The aim of the present study was to develop a risk assessment scale for predicting incident functional disability among older adults. METHODS:We used prospective cohort data from the Japan Gerontological Evaluation Study, a nationwide survey of 90 889 functionally independent older people collected from 23 municip...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.13503
更新日期:2018-10-01 00:00:00
abstract:AIM:Postoperative cognitive dysfunction is often observed in older patients. Previous reports described the link between postoperative cognitive dysfunction and general anesthetics, such as sevoflurane, but the exact mechanism remains unclear. We therefore sought to characterize the effects of sevoflurane on hippocampa...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.13619
更新日期:2019-04-01 00:00:00
abstract:AIM:Falls are a prevalent issue for the older population, and for the healthcare system in terms of emergency department (ED) access and hospitalizations. There is still a lack of knowledge and guidelines, however, regarding the need to hospitalize older patients accessing the ED after a fall. In the present study, we ...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.13497
更新日期:2018-09-01 00:00:00
abstract:AIM:To evaluate the safety, tolerability and pharmacokinetic profile of bapineuzumab after a single intravenous injection in Japanese patients with mild to moderate Alzheimer's disease. METHODS:Participants received either a placebo (n = 8), or bapineuzumab 0.15 (n = 6), 0.5 (n = 6), 1.0 (n = 6) or 2.0 (n = 6) mg/kg. ...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/ggi.12516
更新日期:2016-05-01 00:00:00
abstract:AIM:The main objective of this study was the validation of a brief support instrument for the diagnosis of insomnia in older adults. METHODS:An observational study was carried out for the evaluation of the Insomnia in the Elderly Scale using the psychiatric interview as the gold standard. Data was collected in a prima...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/j.1447-0594.2012.00958.x
更新日期:2013-07-01 00:00:00