Outcomes in Peritoneal Dissemination from Signet Ring Cell Carcinoma of the Appendix Treated with Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy.

Abstract:

BACKGROUND:Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS/HIPEC) is standard treatment for peritoneal dissemination from appendiceal cancer (AC); however, its role in high-grade histopathologic subtypes (high-grade mucinous carcinoma peritonei [HGMCP] and HGMCP with signet ring cells [HGMCP-S]) is controversial due to their aggressive behavior. This study analyzed clinical outcomes of high-grade AC after CRS/HIPEC. METHODS:A prospective database of CRS/HIPEC procedures for HGMCP performed from 1998-2017 was reviewed. Perioperative variables and survival were analyzed. RESULTS:Eighty-six HGMCP and 65 HGMCP-S were identified. HGMCP had more positive tumor markers (TM) (CEA/CA-125/CA-19-9) than HGMCP-S (63% vs 40%, p = 0.005). HGMCP had higher Peritoneal Cancer Index (32 vs 26, p = 0.097) and was less likely to have positive lymph nodes (LN) than HGMCP-S (28% vs 69%, p = < 0.001). Complete cytoreduction was achieved in 84% and 83%, respectively. PFS at 3- and 5-years was 59% and 48% for HGMCP vs 31% and 14% for HGMCP-S. Median PFS was 4.3 and 1.6 years, respectively (p < 0.001). OS at 3- and 5-years was 84% and 64% in HGMCP vs 38% and 25% in HGMCP-S. Median OS was 7.5 and 2.2 years, respectively (p < 0.001). LN negative HGMCP-S had longer median PFS and OS than LN positive HGMCP-S (PFS: 3.4 vs 1.5 years, p = 0.03; OS: 5.6 vs 2.1 months, p = 0.021). CONCLUSIONS:The aggressive histology of HGMCP-S is associated with poor OS, has fewer abnormal TM, and is more likely to have positive LN. However, CRS/HIPEC can achieve a 5-year survival of 25%, which may improve to 51% with negative LN.

journal_name

Ann Surg Oncol

authors

Munoz-Zuluaga C,Sardi A,King MC,Nieroda C,Sittig M,MacDonald R,Gushchin V

doi

10.1245/s10434-018-7007-3

subject

Has Abstract

pub_date

2019-02-01 00:00:00

pages

473-481

issue

2

eissn

1068-9265

issn

1534-4681

pii

10.1245/s10434-018-7007-3

journal_volume

26

pub_type

杂志文章
  • Surgery versus intra-arterial therapy for neuroendocrine liver metastasis: a multicenter international analysis.

    abstract:BACKGROUND:Management of patients with neuroendocrine liver metastasis (NELM) remains controversial. We sought to examine the relative efficacy of surgical management versus intra-arterial therapy (IAT) for NELM and determine factors predictive of survival. METHODS:A total of 753 patients who had surgery (n = 339) or ...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章,多中心研究

    doi:10.1245/s10434-011-1832-y

    authors: Mayo SC,de Jong MC,Bloomston M,Pulitano C,Clary BM,Reddy SK,Clark Gamblin T,Celinski SA,Kooby DA,Staley CA,Stokes JB,Chu CK,Arrese D,Ferrero A,Schulick RD,Choti MA,Geschwind JF,Strub J,Bauer TW,Adams RB,Aldrighett

    更新日期:2011-12-01 00:00:00

  • Most pancreatic cancer resections are R1 resections.

    abstract:BACKGROUND:Curative resection has been shown to be one of the key factors influencing survival of pancreatic ductal adenocarcinoma (PDAC) patients. Although general guidelines for the processing of pancreatic specimens have been established, there is currently no widely accepted standardized protocol for pathological e...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-008-9839-8

    authors: Esposito I,Kleeff J,Bergmann F,Reiser C,Herpel E,Friess H,Schirmacher P,Büchler MW

    更新日期:2008-06-01 00:00:00

  • Epidermal growth factor-containing fibulin-like extracellular matrix protein 1, EFEMP1, a novel tumor-suppressor gene detected in hepatocellular carcinoma using double combination array analysis.

    abstract:BACKGROUND:Although hepatocellular carcinoma (HCC) is one of the commonest cancers worldwide, the underlying molecular mechanisms contributing to hepatocarcinogenesis are still not clear. METHODS:In this study, we performed double array analysis, consisting of both expression profiling and karyotyping analysis using s...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-009-0790-0

    authors: Nomoto S,Kanda M,Okamura Y,Nishikawa Y,Qiyong L,Fujii T,Sugimoto H,Takeda S,Nakao A

    更新日期:2010-03-01 00:00:00

  • Intraperitoneal Administration of Paclitaxel Combined with S-1 Plus Oxaliplatin as Induction Therapy for Patients with Advanced Gastric Cancer with Peritoneal Metastases.

    abstract:BACKGROUND:Intraperitoneal (IP) administration of paclitaxel (PTX) has a great pharmacokinetic advantage to control peritoneal lesions and can be combined with various systemic chemotherapies. In this study, we evaluate the efficacy and tolerability of a combination of IP-PTX and systemic S-1/oxaliplatin (SOX) for indu...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-020-09388-4

    authors: Saito S,Yamaguchi H,Ohzawa H,Miyato H,Kanamaru R,Kurashina K,Hosoya Y,Lefor AK,Sata N,Kitayama J

    更新日期:2020-12-03 00:00:00

  • Laparoscopic HIPEC for Low-Volume Peritoneal Metastasis in Gastric and Gastroesophageal Adenocarcinoma.

    abstract:BACKGROUND:We seek to determine whether laparoscopic hyperthermic intraperitoneal chemoperfusion (LS-HIPEC) improves overall survival (OS) in patients with gastric and gastroesophageal adenocarcinoma and low-volume peritoneal metastasis compared with standard of care treatment. PATIENTS AND METHODS:We reviewed data fr...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-020-08968-8

    authors: Blumenthaler AN,Allen CJ,Ikoma N,Blum M,Das P,Minsky BD,Mansfield PF,Ajani JA,Badgwell BD

    更新日期:2020-12-01 00:00:00

  • Verification of the Optimal Interval Before Esophagectomy After Preoperative Neoadjuvant Chemoradiotherapy for Locally Advanced Thoracic Esophageal Cancer.

    abstract:BACKGROUND:The interval between preoperative chemoradiotherapy and surgery reportedly affects perioperative outcomes and survival; however, the optimal interval in esophageal cancer patients remains uncertain. OBJECTIVE:Our aim was to determine whether a prolonged interval between preoperative neoadjuvant chemoradioth...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-020-09206-x

    authors: Wakita A,Motoyama S,Sato Y,Nagaki Y,Fujita H,Terata K,Imai K,Minamiya Y

    更新日期:2020-10-13 00:00:00

  • Systematic para-aortic and pelvic lymphadenectomy in early stage epithelial ovarian cancer: a prospective study.

    abstract:BACKGROUND:Lymphadenectomy is important in the surgical treatment of apparent early epithelial ovarian cancers (eEOC); however, its extent is not well defined. We evaluated the role of systematic lymphadenectomy, the risk factors related with lymph node metastases, the implications, and the morbidity of comprehensive s...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-012-2439-7

    authors: Ditto A,Martinelli F,Reato C,Kusamura S,Solima E,Fontanelli R,Haeusler E,Raspagliesi F

    更新日期:2012-11-01 00:00:00

  • Sentinel lymph node biopsy using intraoperative indocyanine green fluorescence imaging navigated with preoperative CT lymphography for superficial esophageal cancer.

    abstract:BACKGROUND:The sentinel lymph node (SLN) concept has been gaining attention for gastrointestinal neoplasms but remains controversial for esophageal cancer. This study evaluated the feasibility of SLN identification using intraoperative indocyanine green (ICG) fluorescence imaging (IGFI) navigated by preoperative comput...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-011-1922-x

    authors: Yuasa Y,Seike J,Yoshida T,Takechi H,Yamai H,Yamamoto Y,Furukita Y,Goto M,Minato T,Nishino T,Inoue S,Fujiwara S,Tangoku A

    更新日期:2012-02-01 00:00:00

  • Clinical and pathologic factors associated with distant metastasis and survival in patients with thin primary cutaneous melanoma.

    abstract:BACKGROUND:Approximately 3-5% of patients with thin (≤ 1 mm) cutaneous melanomas develop distant metastases. We sought to identify clinical and pathologic factors associated with distant metastasis and survival in a large number of patients with thin melanoma treated at a single institution. METHODS:We identified pati...

    journal_title:Annals of surgical oncology

    pub_type: 临床试验,杂志文章

    doi:10.1245/s10434-012-2265-y

    authors: Murali R,Haydu LE,Long GV,Quinn MJ,Saw RP,Shannon K,Spillane AJ,Stretch JR,Kefford RF,Thompson JF,Scolyer RA

    更新日期:2012-06-01 00:00:00

  • Reappraisal of conventional risk stratification for local recurrence based on clinical outcomes in 285 resected phyllodes tumors of the breast.

    abstract:PURPOSE:To ensure a surgical margin of ≥1 cm for the effective treatment of phyllodes tumors of the breast (PTB) a second resection has been recommended, but the outcomes of an extensive series of cases employing the aforementioned criterion cast doubt on this clinical approach. The aim of this study was to identify th...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-015-4395-5

    authors: Yom CK,Han W,Kim SW,Park SY,Park IA,Noh DY

    更新日期:2015-09-01 00:00:00

  • Robot versus laparoscopic gastrectomy for cancer by an experienced surgeon: comparisons of surgery, complications, and surgical stress.

    abstract:BACKGROUND:No previous robotic studies present an equivalent surgical quality comparison in an experienced setting for gastric cancer. In addition, a reliable postoperative complication assessment is needed to accurately evaluate surgical outcomes. METHODS:After 20 cases of robotic-assisted gastrectomy (RAG), a total ...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-012-2679-6

    authors: Hyun MH,Lee CH,Kwon YJ,Cho SI,Jang YJ,Kim DH,Kim JH,Park SH,Mok YJ,Park SS

    更新日期:2013-04-01 00:00:00

  • Extrahepatic disease should not preclude transarterial chemoembolization for metastatic neuroendocrine carcinoma.

    abstract:BACKGROUND:Transarterial chemoembolization (TACE) is often utilized for patients with inoperable neuroendocrine carcinoma liver metastases. Often, metastatic disease is not limited to the liver. The impact of extrahepatic disease (EHD) on outcomes and response after TACE has not been described. METHODS:We reviewed 192...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-012-2786-4

    authors: Arrese D,McNally ME,Chokshi R,Feria-Arias E,Schmidt C,Klemanski D,Gregory G,Khabiri H,Shah M,Bloomston M

    更新日期:2013-04-01 00:00:00

  • Central compartment reoperation for recurrent/persistent differentiated thyroid cancer: patterns of recurrence, morbidity, and prediction of postoperative hypocalcemia.

    abstract:BACKGROUND:Incidence rates of hypoparathyroidism and vocal cord paralysis are high following central compartment reoperation, but few prospective studies have assessed morbidities and factors predictive of hypocalcemia after reoperation. We investigated recurrence patterns, morbidity, and factors predictive of postoper...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-010-1470-9

    authors: Roh JL,Kim JM,Park CI

    更新日期:2011-05-01 00:00:00

  • Detection of sentinel node in gastric cancer surgery by indocyanine green fluorescence imaging: comparison with infrared imaging.

    abstract:BACKGROUND:Secure methods for clinical detection of the sentinel node (SN) are in great demand to avoid unnecessary resection. This was a clinical exploration/feasibility study of a novel detection system for SN biopsy using indocyanine green (ICG) fluorescence imaging in gastric cancer surgery. METHODS:SN biopsy usin...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-008-9872-7

    authors: Miyashiro I,Miyoshi N,Hiratsuka M,Kishi K,Yamada T,Ohue M,Ohigashi H,Yano M,Ishikawa O,Imaoka S

    更新日期:2008-06-01 00:00:00

  • Long-term survival after multidisciplinary management of resected pancreatic adenocarcinoma.

    abstract:INTRODUCTION:Actual 5-year survival rates of 10-18% have been reported for patients with resected pancreatic adenocarcinoma (PC), but the use of multimodality therapy was uncommon in these series. We evaluated long-term survival and patterns of recurrence in patients treated for PC with contemporary staging and multimo...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-008-0295-2

    authors: Katz MH,Wang H,Fleming JB,Sun CC,Hwang RF,Wolff RA,Varadhachary G,Abbruzzese JL,Crane CH,Krishnan S,Vauthey JN,Abdalla EK,Lee JE,Pisters PW,Evans DB

    更新日期:2009-04-01 00:00:00

  • Increasing mastectomy rates-the effect of environmental factors on the choice for mastectomy: a comparative analysis between Canada and the United States.

    abstract:PURPOSE:Unilateral mastectomy (UM) and contralateral prophylactic mastectomy (CPM) for early-stage breast cancer (ESBC) have been increasing. Numerous etiological factors for this rise have been suggested, including increasing use of magnetic resonance imaging (MRI) and reconstruction, surgeon's preference, and patient...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-014-3955-4

    authors: Covelli AM,Baxter NN,Fitch MI,Wright FC

    更新日期:2014-10-01 00:00:00

  • Impact of multifocal or multicentric disease on surgery and locoregional, distant and overall survival of 6,134 breast cancer patients treated with neoadjuvant chemotherapy.

    abstract:BACKGROUND:The impact of tumor focality on type of surgery, local recurrence rate, and survival after neoadjuvant chemotherapy (NACT) for breast cancer is not fully understood. This study aimed to compare local recurrence-free survival (LRFS), disease-free survival (DFS), and overall survival (OS) according to focality...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1245/s10434-014-4122-7

    authors: Ataseven B,Lederer B,Blohmer JU,Denkert C,Gerber B,Heil J,Kühn T,Kümmel S,Rezai M,Loibl S,von Minckwitz G

    更新日期:2015-04-01 00:00:00

  • Polymorphisms of p16, p27, p73, and MDM2 modulate response and survival of pancreatic cancer patients treated with preoperative chemoradiation.

    abstract::Genetic polymorphisms play an important role in clinical response to cytotoxic therapies. We hypothesized that polymorphisms in cell cycle genes may modulate response to preoperative chemoradiation and survival of pancreatic cancer patients. We evaluated 12 single-nucleotide polymorphisms (SNPs) of ten cell cycle gene...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-008-0220-8

    authors: Chen J,Li D,Killary AM,Sen S,Amos CI,Evans DB,Abbruzzese JL,Frazier ML

    更新日期:2009-02-01 00:00:00

  • Current status and future prospects of sentinel node navigational surgery for gastrointestinal cancers.

    abstract::Until the late 1990s, the application of the sentinel node (SN) concept to gastrointestinal (GI) malignancies was not recognized because of the multidirectional and complicated lymphatic flow from the GI tract. However, several studies supporting the validity of the SN concept for GI cancers have been reported in the ...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章,评审

    doi:10.1007/BF02523637

    authors: Kitagawa Y,Fujii H,Mukai M,Kubo A,Kitajima M

    更新日期:2004-03-01 00:00:00

  • Differences in Treatment and Outcome of Pancreatic Adenocarcinoma Stage I and II in the EURECCA Pancreas Consortium.

    abstract:BACKGROUND:The EUropean REgistration of Cancer CAre (EURECCA) consortium aims to investigate differences in treatment and to improve cancer care through Europe. The purpose of this study was to compare neo- and adjuvant chemotherapy (ACT) and outcome after tumor resection for pancreatic adenocarcinoma stage I and II in...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章,多中心研究

    doi:10.1245/s10434-018-6705-1

    authors: Groen JV,Sibinga Mulder BG,van Eycken E,Valerianova Z,Borras JM,van der Geest LGM,Capretti G,Schlesinger-Raab A,Primic-Zakelj M,Ryzhov A,van de Velde CJH,Bonsing BA,Bastiaannet E,Mieog JSD

    更新日期:2018-11-01 00:00:00

  • Concurrent Selective Lymph Node Radiotherapy and S-1 Plus Cisplatin for Esophageal Squamous Cell Carcinoma: A Phase II Study.

    abstract:BACKGROUND:The efficacy, toxicity, and patterns of failure of esophageal squamous cell carcinoma (ESCC) treated with selective lymph node (SLN) conventional fraction radiotherapy (CFRT) and S-1 plus cisplatin (CDDP) were evaluated. PATIENTS AND METHODS:67 Patients with clinical stage II-IVa ESCC were enrolled. The tot...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-019-07264-4

    authors: Wang X,Liu X,Li D,Wang X,Huang W,Li B

    更新日期:2019-06-01 00:00:00

  • Induction of p21WAF1 expression protects HT29 colon cancer cells from apoptosis induced by cryoinjury.

    abstract:BACKGROUND:Cryotherapy is a method of in situ destruction of tumors by freeze/thaw mechanisms. Cancer cells located in the peripheral zone of the tumor undergoing cryotherapy can die by apoptosis. We hypothesized that p21WAF1 is involved in the mediation of cryotherapy-induced apoptosis. METHODS:HT29 cells grown on a ...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/ASO.2005.11.021

    authors: Sharma RR,Ravikumar TS,Raimo D,Yang WL

    更新日期:2005-09-01 00:00:00

  • Parietal pleurectomy for malignant pleural effusion.

    abstract:BACKGROUND:Malignant pleural effusions are seen frequently in clinical practice and are most commonly caused by breast cancer and lung cancer. Standard treatment usually consists of complete drainage of the pleural space via a chest tube and instillation of a pleural irritant to obtain pleural symphysis. In a majority ...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1007/BF02303632

    authors: Fry WA,Khandekar JD

    更新日期:1995-03-01 00:00:00

  • Long-Term Impact of Postoperative Complications on Cancer Recurrence Following Lung Cancer Surgery.

    abstract:BACKGROUND:Postoperative complications are associated with poor cancer-specific survival in various types of cancer surgery. Recent studies suggest that systemic inflammation induced by surgical trauma can accelerate the adhesion of circulating tumor cells to the vascular endothelium of distant organs, resulting in ear...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-016-5655-8

    authors: Nojiri T,Hamasaki T,Inoue M,Shintani Y,Takeuchi Y,Maeda H,Okumura M

    更新日期:2017-04-01 00:00:00

  • Clinical Utility of the 12-Gene DCIS Score Assay: Impact on Radiotherapy Recommendations for Patients with Ductal Carcinoma In Situ.

    abstract:OBJECTIVE:The aim of this study was to determine the impact of the results of the 12-gene DCIS Score assay on (i) radiotherapy recommendations for patients with pure ductal carcinoma in situ (DCIS) following breast-conserving surgery (BCS), and (ii) patient decisional conflict and state anxiety. METHODS:Thirteen sites...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章,多中心研究

    doi:10.1245/s10434-016-5583-7

    authors: Manders JB,Kuerer HM,Smith BD,McCluskey C,Farrar WB,Frazier TG,Li L,Leonard CE,Carter DL,Chawla S,Medeiros LE,Guenther JM,Castellini LE,Buchholz DJ,Mamounas EP,Wapnir IL,Horst KC,Chagpar A,Evans SB,Riker AI,Vali F

    更新日期:2017-03-01 00:00:00

  • Patterns of Lymph Node Recurrence in Adrenocortical Carcinoma: Possible Implications for Primary Surgical Treatment.

    abstract:BACKGROUND:In the surgical treatment of adrenocortical carcinoma (ACC), lymphadenectomy may improve oncologic outcome. However, patterns of metastatic lymphatic spread in ACC are unknown. METHODS:Clinical data of patients included in the European Network for the Study of Adrenal Tumors (ENSAT) registry were retrospect...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-018-6999-z

    authors: Reibetanz J,Rinn B,Kunz AS,Flemming S,Ronchi CL,Kroiss M,Deutschbein T,Pulzer A,Hahner S,Kocot A,Germer CT,Fassnacht M,Jurowich C

    更新日期:2019-02-01 00:00:00

  • Comparison of cases captured in the national cancer data base with those in population-based central cancer registries.

    abstract:BACKGROUND:The National Cancer Data Base (NCDB) is a large, geographically diverse hospital-based cancer registry that has been used to study factors related to cancer diagnosis, treatment, and survival. The primary purpose of this study was to compare the case counts and characteristics of patients in NCDB with popula...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-013-2901-1

    authors: Lerro CC,Robbins AS,Phillips JL,Stewart AK

    更新日期:2013-06-01 00:00:00

  • Quilting prevents seroma formation following breast cancer surgery: closing the dead space by quilting prevents seroma following axillary lymph node dissection and mastectomy.

    abstract:BACKGROUND:Seroma is a frequent problem after mastectomy (ME) and axillary lymph node dissection (ALND). Seroma is associated with pain, discomfort, impaired mobilisation and repeated aspirations, often resulting in a surgical site infection (SSI). It has already been demonstrated that minimizing dead space through fix...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-013-3359-x

    authors: ten Wolde B,van den Wildenberg FJ,Keemers-Gels ME,Polat F,Strobbe LJ

    更新日期:2014-03-01 00:00:00

  • Comparison of Tissue and Blood Concentrations of Oxaliplatin Administrated by Different Modalities of Intraperitoneal Chemotherapy.

    abstract:BACKGROUND:Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is a new technology for delivering intraperitoneal chemotherapy. It is generally assumed that with PIPAC, the ratio of peritoneal to systemic drug concentration is superior to liquid hyperthermic intraperitoneal chemotherapy (HIPEC). To date, no direct...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-019-07695-z

    authors: Giger-Pabst U,Bucur P,Roger S,Falkenstein TA,Tabchouri N,Le Pape A,Lerondel S,Demtröder C,Salamé E,Ouaissi M

    更新日期:2019-12-01 00:00:00

  • Follow-Up Recommendations after Diagnosis of Primary Cutaneous Melanoma: A Population-Based Study in New South Wales, Australia.

    abstract:BACKGROUND:Follow-up practices after diagnosis and treatment of primary cutaneous melanoma vary considerably. We aimed to determine factors associated with recommendations for follow-up setting, frequency, skin surveillance, and concordance with clinical guidelines. METHODS:The population-based Melanoma Patterns of Ca...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-017-6319-z

    authors: Read RL,Madronio CM,Cust AE,Goumas C,Watts CG,Menzies S,Curtin AM,Mann G,Thompson JF,Morton RL

    更新日期:2018-03-01 00:00:00