A novel dry-bonding approach to reduce collagen degradation and optimize resin-dentin interfaces.

Abstract:

:In dentistry, the wet-bonding approach relies on water to maintain demineralized collagen expanded for proper resin infiltration; nevertheless, hydrolytic instability of the resin-dentin interface is inevitable with current bonding techniques. Considering dimethyl sulfoxide's (DMSO) ability to "biomodify" collagen and precipitate enzymes, the aim was to test whether the use of DMSO would permit adequate resin bonding to H3PO4-etched dehydrated dentin and assess its impact on collagen degradation by host-derived enzymes. Etched dentin surfaces from extracted sound human molars were randomly bonded in wet or dry conditions using aqueous or ethanolic DMSO solutions as pretreatments and bonding resins with or without DMSO. Bonded teeth were sectioned into resin-dentin slabs for confocal in situ zymography and beams for microtensile bond strength test. Demineralized powdered dentin was incubated in the tested DMSO -media and a hydroxyproline assay evaluated dissolution of collagen peptides. Zymography was performed on protein extracts obtained from dry and wet H3PO4-ecthed dentin powder treated with the DMSO- media. The correlative biochemical analysis demonstrated that reduction of water content during dentin hybridization by the innovative dry-bonding approaches with DMSO is effective to inactivate host-derived MMP-2 and MMP-9 and thus reduce collagen degradation while simultaneously optimizing resin-dentin bonding.

journal_name

Sci Rep

journal_title

Scientific reports

authors

Stape THS,Seseogullari-Dirihan R,Tjäderhane L,Abuna G,Martins LRM,Tezvergil-Mutluay A

doi

10.1038/s41598-018-34726-8

subject

Has Abstract

pub_date

2018-11-15 00:00:00

pages

16890

issue

1

issn

2045-2322

pii

10.1038/s41598-018-34726-8

journal_volume

8

pub_type

杂志文章
  • A new way to synthesize superconducting metal-intercalated C60 and FeSe.

    abstract::Doping with the optimum concentration of carriers (electrons or holes) can modify the physical properties of materials. Therefore, improved ways to achieve carrier doping have been pursued extensively for more than 50 years. Metal-intercalation is one of the most important techniques for electron doping of organic / i...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep18931

    authors: Takahei Y,Tomita K,Itoh Y,Ashida K,Lee JH,Nishimoto N,Kimura T,Kudo K,Nohara M,Kubozono Y,Kambe T

    更新日期:2016-01-06 00:00:00

  • Age and sex subgroups vulnerable to copycat suicide: evaluation of nationwide data in South Korea.

    abstract::Media reports of a celebrity's suicide may be followed by copycat suicides, and the impact may vary in different age and sex subgroups. We proposed a quantitative framework to assess the vulnerability of age and sex subgroups to copycat suicide and used this method to investigate copycat suicides in relation to the su...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-53833-8

    authors: Yi H,Hwang J,Bae HJ,Kim N

    更新日期:2019-11-21 00:00:00

  • Ordering Ag nanowire arrays by a glass capillary: a portable, reusable and durable SERS substrate.

    abstract::Assembly of nanowires into ordered macroscopic structures with new functionalities has been a recent focus. In this Letter, we report a new route for ordering hydrophilic Ag nanowires with high aspect ratio by flowing through a glass capillary. The present glass capillary with well-defined silver nanowire films inside...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep00987

    authors: Liu JW,Wang JL,Huang WR,Yu L,Ren XF,Wen WC,Yu SH

    更新日期:2012-01-01 00:00:00

  • The intracellular trafficking mechanism of Lipofectamine-based transfection reagents and its implication for gene delivery.

    abstract::Lipofectamine reagents are widely accepted as "gold-standard" for the safe delivery of exogenous DNA or RNA into cells. Despite this, a satisfactory mechanism-based explanation of their superior efficacy has remained mostly elusive thus far. Here we apply a straightforward combination of live cell imaging, single-part...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep25879

    authors: Cardarelli F,Digiacomo L,Marchini C,Amici A,Salomone F,Fiume G,Rossetta A,Gratton E,Pozzi D,Caracciolo G

    更新日期:2016-05-11 00:00:00

  • Feasibility and accuracy of a robotic guidance system for navigated spine surgery in a hybrid operating room: a cadaver study.

    abstract::The combination of navigation and robotics in spine surgery has the potential to accurately identify and maintain bone entry position and planned trajectory. The goal of this study was to examine the feasibility, accuracy and efficacy of a new robot-guided system for semi-automated, minimally invasive, pedicle screw p...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-64462-x

    authors: Burström G,Balicki M,Patriciu A,Kyne S,Popovic A,Holthuizen R,Homan R,Skulason H,Persson O,Edström E,Elmi-Terander A

    更新日期:2020-05-05 00:00:00

  • Comparison of Alterations in miRNA Expression in Matched Tissue and Blood Samples during Spinal Cord Glioma Progression.

    abstract::Abnormal expression of microRNAs (miRNAs) contributes to glioma initiation. However, the expression of miRNAs in tumour tissue or blood of spinal cord glioma (SCG) patients, particularly in high-grade spinal gliomas (Grade IV) known as glioblastoma (GBM), remains largely unknown. In this study we aimed to determine di...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-42364-x

    authors: An T,Fan T,Zhang XQ,Liu YF,Huang J,Liang C,Lv BH,Wang YQ,Zhao XG,Liu JX,Fu YH,Jiang GJ

    更新日期:2019-06-24 00:00:00

  • A versatile clearing agent for multi-modal brain imaging.

    abstract::Extensive mapping of neuronal connections in the central nervous system requires high-throughput µm-scale imaging of large volumes. In recent years, different approaches have been developed to overcome the limitations due to tissue light scattering. These methods are generally developed to improve the performance of a...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep09808

    authors: Costantini I,Ghobril JP,Di Giovanna AP,Allegra Mascaro AL,Silvestri L,Müllenbroich MC,Onofri L,Conti V,Vanzi F,Sacconi L,Guerrini R,Markram H,Iannello G,Pavone FS

    更新日期:2015-05-07 00:00:00

  • Pedigree-based genome re-sequencing reveals genetic variation patterns of elite backbone varieties during modern rice improvement.

    abstract::Rice breeding has achieved great productivity improvements by semi-dwarf varieties and hybrid vigour. Due to poor understanding of genetic basis of elite backbone varieties, the continuous increasing in rice yield still faces great challenges. Here, 52 elite rice varieties from three historical representative pedigree...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-00415-1

    authors: Zheng X,Li L,Liang F,Tan C,Tang S,Yu S,Diao Y,Li S,Hu Z

    更新日期:2017-03-22 00:00:00

  • Microbial structure and function in infant and juvenile rhesus macaques are primarily affected by age, not vaccination status.

    abstract::Although thimerosal, an ethylmercury-based preservative, has been removed from most pediatric vaccines in the United States, some multidose vaccines, such as influenza vaccines, still contain thimerosal. Considering that a growing number of studies indicate involvement of the gut microbiome in infant immune developmen...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-34019-0

    authors: Hasegawa Y,Curtis B,Yutuc V,Rulien M,Morrisroe K,Watkins K,Ferrier C,English C,Hewitson L,Slupsky CM

    更新日期:2018-10-26 00:00:00

  • Evidence for trivial Berry phase and absence of chiral anomaly in semimetal NbP.

    abstract::The discovery of Weyl semimetals (WSM) has brought forth the condensed matter realization of Weyl fermions, which were previously theorized as low energy excitations in high energy particle physics. Recently, transition metal mono-pnictides are under intense investigation for understanding properties of inversion-symm...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep46062

    authors: Sudesh,Kumar P,Neha P,Das T,Patnaik S

    更新日期:2017-04-10 00:00:00

  • Predicted impact of thermal power generation emission control measures in the Beijing-Tianjin-Hebei region on air pollution over Beijing, China.

    abstract::Widespread economic growth in China has led to increasing episodes of severe air pollution, especially in major urban areas. Thermal power plants represent a particularly important class of emissions. Here we present an evaluation of the predicted effectiveness of a series of recently proposed thermal power plant emis...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-19481-0

    authors: Wang L,Li P,Yu S,Mehmood K,Li Z,Chang S,Liu W,Rosenfeld D,Flagan RC,Seinfeld JH

    更新日期:2018-01-17 00:00:00

  • Uncovering hidden nodes in complex networks in the presence of noise.

    abstract::Ascertaining the existence of hidden objects in a complex system, objects that cannot be observed from the external world, not only is curiosity-driven but also has significant practical applications. Generally, uncovering a hidden node in a complex network requires successful identification of its neighboring nodes, ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep03944

    authors: Su RQ,Lai YC,Wang X,Do Y

    更新日期:2014-02-03 00:00:00

  • Thioesterase YbgC affects motility by modulating c-di-GMP levels in Shewanella oneidensis.

    abstract::Because of ubiquity of thioesters, thioesterases play a critical role in metabolism, membrane biosynthesis, signal transduction, and gene regulation. In many bacteria, YbgC is such an enzyme, whose coding gene mostly resides in the tol-pal cluster. Although all other proteins encoded in the tol-pal cluster are clearly...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-04285-5

    authors: Gao T,Meng Q,Gao H

    更新日期:2017-06-21 00:00:00

  • C-terminal short arginine/serine repeat sequence-dependent regulation of Y14 (RBM8A) localization.

    abstract::Y14 (RBM8A) is an RNA recognition motif-containing protein that forms heterodimers with MAGOH and serves as a core factor of the RNA surveillance machinery for the exon junction complex (EJC). The role of the Y14 C-terminal serine/arginine (RS) repeat-containing region, which has been reported to undergo modifications...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-18765-1

    authors: Tatsuno T,Ishigaki Y

    更新日期:2018-01-12 00:00:00

  • Multi-layer electrode with nano-Li4Ti5O12 aggregates sandwiched between carbon nanotube and graphene networks for high power Li-ion batteries.

    abstract::Self-aggregated Li4Ti5O12 particles sandwiched between graphene nanosheets (GNSs) and single-walled carbon nanotubes (SWCNTs) network are reported as new hybrid electrodes for high power Li-ion batteries. The multi-layer electrodes are fabricated by sequential process comprising air-spray coating of GNSs layer and the...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep07334

    authors: Choi JH,Ryu WH,Park K,Jo JD,Jo SM,Lim DS,Kim ID

    更新日期:2014-12-05 00:00:00

  • Viral fusion efficacy of specific H3N2 influenza virus reassortant combinations at single-particle level.

    abstract::Virus pseudotyping is a useful and safe technique for studying entry of emerging strains of influenza virus. However, few studies have compared different reassortant combinations in pseudoparticle systems, or compared entry kinetics of native viruses and their pseudotyped analogs. Here, vesicular stomatitis virus (VSV...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep35537

    authors: Hsu HL,Millet JK,Costello DA,Whittaker GR,Daniel S

    更新日期:2016-10-18 00:00:00

  • Pollinator foraging flexibility mediates rapid plant-pollinator network restoration in semi-natural grasslands.

    abstract::We examined how plant-pollinator interactions were affected by time since habitat restoration and landscape connectivity by comparing plant-pollinator networks in restored, abandoned and continuously grazed semi-natural pastures in south-central Sweden. We measured richness of flowering plants and pollinators, and loc...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-51912-4

    authors: Noreika N,Bartomeus I,Winsa M,Bommarco R,Öckinger E

    更新日期:2019-10-29 00:00:00

  • Comparison of the safety and efficacy of triple sequential therapy and transscleral cyclophotocoagulation for neovascular glaucoma in the angle-closure stage.

    abstract::To compare the efficacy and safety of triple therapy combining intravitreal injection of anti-vascular endothelial growth factor, trabeculectomy, and pan-retinal photocoagulation via binocular indirect ophthalmoscopy, with that of transscleral cyclophotocoagulation (TCP) to treat neovascular glaucoma in the angle-clos...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-25394-9

    authors: Hong Y,Hu Y,Dou H,Wang C,Zhang C,Ma Z

    更新日期:2018-05-04 00:00:00

  • Characterization of cereblon-dependent targeted protein degrader by visualizing the spatiotemporal ternary complex formation in cells.

    abstract::Targeted protein degradation (TPD) through a proteasome-dependent pathway induced by heterofunctional small molecules is initiated by the formation of a ternary complex with recruited E3 ligases. This complex formation affects the degradation ability of TPD molecules, and thus we tested for visualization of the intrac...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-59966-5

    authors: Kaji T,Koga H,Kuroha M,Akimoto T,Hayata K

    更新日期:2020-02-20 00:00:00

  • Predictive feedback to V1 dynamically updates with sensory input.

    abstract::Predictive coding theories propose that the brain creates internal models of the environment to predict upcoming sensory input. Hierarchical predictive coding models of vision postulate that higher visual areas generate predictions of sensory inputs and feed them back to early visual cortex. In V1, sensory inputs that...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-16093-y

    authors: Edwards G,Vetter P,McGruer F,Petro LS,Muckli L

    更新日期:2017-11-28 00:00:00

  • Ca(2+) dynamics in oocytes from naturally-aged mice.

    abstract::The ability of human metaphase-II arrested eggs to activate following fertilisation declines with advancing maternal age. Egg activation is triggered by repetitive increases in intracellular Ca(2+) concentration ([Ca(2+)]i) in the ooplasm as a result of sperm-egg fusion. We therefore hypothesised that eggs from older ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep19357

    authors: Haverfield J,Nakagawa S,Love D,Tsichlaki E,Nomikos M,Lai FA,Swann K,FitzHarris G

    更新日期:2016-01-20 00:00:00

  • The neurophysiological architecture of semantic dementia: spectral dynamic causal modelling of a neurodegenerative proteinopathy.

    abstract::The selective destruction of large-scale brain networks by pathogenic protein spread is a ubiquitous theme in neurodegenerative disease. Characterising the circuit architecture of these diseases could illuminate both their pathophysiology and the computational architecture of the cognitive processes they target. Howev...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-72847-1

    authors: Benhamou E,Marshall CR,Russell LL,Hardy CJD,Bond RL,Sivasathiaseelan H,Greaves CV,Friston KJ,Rohrer JD,Warren JD,Razi A

    更新日期:2020-10-01 00:00:00

  • Tuning electronic properties of transition-metal dichalcogenides via defect charge.

    abstract::Defect engineering is a promising route for controlling the electronic properties of monolayer transition-metal dichalcogenide (TMD) materials. Here, we demonstrate that the electronic structure of MoS2 depends sensitively on the defect charge, both its sign and magnitude. In particular, we study shallow bound states ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-31941-1

    authors: Aghajanian M,Mostofi AA,Lischner J

    更新日期:2018-09-11 00:00:00

  • Insights into grapevine defense response against drought as revealed by biochemical, physiological and RNA-Seq analysis.

    abstract::Grapevine is an important and extensively grown fruit crop, which is severely hampered by drought worldwide. So, comprehending the impact of drought on grapevine genetic resources is necessary. In the present study, RNA-sequencing was executed using cDNA libraries constructed from both drought-stress and control plant...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-13464-3

    authors: Haider MS,Zhang C,Kurjogi MM,Pervaiz T,Zheng T,Zhang C,Lide C,Shangguan L,Fang J

    更新日期:2017-10-13 00:00:00

  • Molecular diagnostic assays based on cpn60 UT sequences reveal the geographic distribution of subgroup 16SrXIII-(A/I)I phytoplasma in Mexico.

    abstract::Geographically diverse samples from strawberry exhibiting symptoms of Strawberry Green Petal (SbGP), periwinkle plants with virescence, and blackberry, blueberry, and raspberry plants displaying yellowing and inedible fruits, were assayed for the presence of phytoplasma DNA. PCR targeting the 16S rRNA-encoding gene an...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-00895-1

    authors: Pérez-López E,Rodríguez-Martínez D,Olivier CY,Luna-Rodríguez M,Dumonceaux TJ

    更新日期:2017-04-19 00:00:00

  • Polarization-independent split bull's eye antennas for infrared nano-photodetectors.

    abstract::Split bull's eye (SBE) antennas exhibit much larger extraordinary optical transmission and strong polarization dependence rather than bull's eye (BE) antennas in the infrared range due to the introduced sub-wavelength slit. Here, we demonstrate a dual-split bull's eye (DSBE) antenna, which consists of two sub-waveleng...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep39106

    authors: Yang M,Ren FF,Pu L,Xiao L,Sheng Y,Wang J,Lu H,Zheng Y,Shi Y

    更新日期:2016-12-19 00:00:00

  • Highly Permeable Graphene Oxide/Polyelectrolytes Hybrid Thin Films for Enhanced CO2/N2 Separation Performance.

    abstract::Separation of CO2 from other gasses offers environmental benefits since CO2 gas is the main contributor to global warming. Recently, graphene oxide (GO) based gas separation membranes are of interest due to their selective barrier properties. However, maintaining selectivity without sacrificing permeance is still chal...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-00433-z

    authors: Heo J,Choi M,Chang J,Ji D,Kang SW,Hong J

    更新日期:2017-03-28 00:00:00

  • The G protein-coupled receptor GPR157 regulates neuronal differentiation of radial glial progenitors through the Gq-IP3 pathway.

    abstract::The ability of radial glial progenitors (RGPs) to generate cortical neurons is determined by local extracellular factors and signaling pathways intrinsic to RGPs. Here we find that GPR157, an orphan G protein-coupled receptor, localizes to RGPs' primary cilia exposed to the cerebrospinal fluid (CSF). GPR157 couples wi...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep25180

    authors: Takeo Y,Kurabayashi N,Nguyen MD,Sanada K

    更新日期:2016-05-04 00:00:00

  • Index markers of chronic fatigue syndrome with dysfunction of TCA and urea cycles.

    abstract::Chronic fatigue syndrome (CFS) is a persistent and unexplained pathological state characterized by exertional and severely debilitating fatigue, with/without infectious or neuropsychiatric symptoms, lasting at least 6 consecutive months. Its pathogenesis remains incompletely understood. Here, we performed comprehensiv...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep34990

    authors: Yamano E,Sugimoto M,Hirayama A,Kume S,Yamato M,Jin G,Tajima S,Goda N,Iwai K,Fukuda S,Yamaguti K,Kuratsune H,Soga T,Watanabe Y,Kataoka Y

    更新日期:2016-10-11 00:00:00

  • Triphenyltin recognition by primary structures of effector proteins and the protein network of Bacillus thuringiensis during the triphenyltin degradation process.

    abstract::Herein, triphenyltin (TPT) biodegradation efficiency and its transformation pathway have been elucidated. To better understand the molecular mechanism of TPT degradation, the interactions between amino acids, primary structures, and quaternary conformations of effector proteins and TPT were studied. The results verifi...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-04014-y

    authors: Wang L,Ye J,Ou H,Qin H,Long Y,Ke J

    更新日期:2017-06-23 00:00:00