Efficacy and safety of Xiaofeng powder (xiao feng san) in treating urticaria: A protocol for a systematic review and meta-analysis of randomized controlled trials.

Abstract:

BACKGROUND:Urticaria is a common skin disease that has a high impact on a patient's daily life. Xiaofeng powder (XFP) is one of the most commonly used Chinese herbal formula in China for urticaria. However, due to the lack of systematic evaluations, its clinical efficacy remains controversial. This meta-analysis was performed to evaluate the effect and safety of XFP for urticaria. METHODS:Seven databases, including Cochrane Central Register of Controlled Trials, PubMed, Embase, the Chinese National Knowledge Infrastructure (CNKI), the Chinese Scientific Journal Database (VIP), the Chinese Biomedical Literature Database (CBM), and the Wanfang Database. The period will be from their inception to September 2018. Randomized controlled trials of XFS used separately against conventional Western medicine therapy in patients with urticarial were included. After the methodologic quality was assessed and the valid data were extracted, RevMan 5.3 software was used for the final meta-analysis. RESULTS:The results will provide evidence regarding the efficacy and safety of XFP in treating urticaria. CONCLUSION:The conclusion of our systematic review will provide evidence to judge whether XFP is an effective intervention for patient with urticaria. This systematic review will be disseminated in peer-reviewed publications. The results of the study will provide evidence concerning the efficacy and safety of Xiaofeng Powder (xiao feng san) in treating urticaria. PROSPERO REGISTRATION NUMBER:PROSPERO CRD 42018087260.

journal_name

Medicine (Baltimore)

journal_title

Medicine

authors

Chen G,Zhao J,Chen T,Zhang Z,Huang C,Xu Z,Xu H

doi

10.1097/MD.0000000000013039

subject

Has Abstract

pub_date

2018-11-01 00:00:00

pages

e13039

issue

45

eissn

0025-7974

issn

1536-5964

pii

00005792-201811090-00023

journal_volume

97

pub_type

杂志文章,meta分析

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