Abstract:
:The production of B-phycoerythrin (B-PE) from the red microalga Porphyridium marinum was optimized before to purify it and subsequently study its antioxidant activities. NaNO3, K2HPO4 and metal traces concentrations of the culture medium, and luminosity parameters were chosen, according to the Plackett-Burman design, as the most influent factors on the B-PE production by P. marinum. The optimization of these factors according to the Box-Behnken plan gave a maximum of B-PE production equal to 40 mg/g dry weight under the following conditions: NaNO3 = 3.4 g/L; K2HPO4 = 0 g/L; light intensity = 70 μmol photons/m2/s and metal solution = 1.5 mL/L. The B-PE also showed an interesting capacity to chelate Fe3+ (IC50 = 13.91 ± 0.21 μg/mL) and a significant reducing power (OD700nm = 0.485 ± 0.011 at 100 μg/mL). The present study reports the antioxidant potential of purified B-PE from P. marinum that could be potentially used as a source of bioactive protein for a wide range of cosmetic and pharmaceutical applications.
journal_name
Int J Biol Macromoljournal_title
International journal of biological macromoleculesauthors
Gargouch N,Karkouch I,Elleuch J,Elkahoui S,Michaud P,Abdelkafi S,Laroche C,Fendri Idoi
10.1016/j.ijbiomac.2018.09.037subject
Has Abstractpub_date
2018-12-01 00:00:00pages
2106-2114issue
Pt Beissn
0141-8130issn
1879-0003pii
S0141-8130(18)33629-8journal_volume
120pub_type
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